Gene Page: CYP27A1

Summary
GeneID  1593
Symbol  CYP27A1
Synonyms  CP27|CTX|CYP27
Description  cytochrome P450, family 27, subfamily A, polypeptide 1
See related  HGNC:2605|MIM:606530|Ensembl:ENSG00000135929|HPRD:05939|
Locus tag  -
Gene type  protein-coding
Map location  2q33-qter
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00916 
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.01016 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
POFUT10.900.90
NCAN0.890.90
ANKFY10.880.89
SEPN10.870.89
SEC61A10.860.86
MAPK1IP1L0.860.85
SALL20.860.86
NLGN30.850.89
PCDHGB8P0.850.89
CYFIP10.850.85
Top 10 negatively co-expressed genes
AF347015.21-0.62-0.75
MT-CO2-0.60-0.68
C5orf53-0.60-0.63
AF347015.31-0.60-0.67
AF347015.27-0.58-0.65
MYL3-0.57-0.60
C1orf54-0.56-0.66
AF347015.33-0.55-0.61
AF347015.8-0.55-0.64
FXYD1-0.55-0.58
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005506iron ion bindingIEA-
GO:0020037heme bindingIEA-
GO:0008395steroid hydroxylase activityEXP1708392 
GO:0008395steroid hydroxylase activityTAS9790667 
GO:0009055electron carrier activityIEA-
GO:0047749cholestanetriol 26-monooxygenase activityIEA-
GO:0046872metal ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0055114oxidation reductionIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005739mitochondrionIEA-
GO:0005743mitochondrial inner membraneIEA-
GO:0005759mitochondrial matrixEXP1708392 
GO:0016020membraneIEA-
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_PRIMARY_BILE_ACID_BIOSYNTHESIS 169All SZGR genes in this pathway
KEGG_PPAR_SIGNALING_PATHWAY 6947All SZGR genes in this pathway
REACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM 2711All SZGR genes in this pathway
REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL 156All SZGR genes in this pathway
REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL 106All SZGR genes in this pathway
REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS 199All SZGR genes in this pathway
REACTOME_BIOLOGICAL_OXIDATIONS 13991All SZGR genes in this pathway
REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE 5134All SZGR genes in this pathway
REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS 7050All SZGR genes in this pathway
REACTOME_ENDOGENOUS_STEROLS 1510All SZGR genes in this pathway
REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 478302All SZGR genes in this pathway
PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_UP 205140All SZGR genes in this pathway
SMIRNOV_CIRCULATING_ENDOTHELIOCYTES_IN_CANCER_UP 158103All SZGR genes in this pathway
CHEBOTAEV_GR_TARGETS_UP 7762All SZGR genes in this pathway
SCHLOSSER_SERUM_RESPONSE_DN 712443All SZGR genes in this pathway
HATADA_METHYLATED_IN_LUNG_CANCER_UP 390236All SZGR genes in this pathway
HSIAO_LIVER_SPECIFIC_GENES 244154All SZGR genes in this pathway
LEIN_PONS_MARKERS 8959All SZGR genes in this pathway
WONG_MITOCHONDRIA_GENE_MODULE 217122All SZGR genes in this pathway
MOOTHA_HUMAN_MITODB_6_2002 429260All SZGR genes in this pathway
MOOTHA_MITOCHONDRIA 447277All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_DN 315201All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_HGF_UP 418282All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_UP 408276All SZGR genes in this pathway
CHANG_CORE_SERUM_RESPONSE_DN 209137All SZGR genes in this pathway
BOYAULT_LIVER_CANCER_SUBCLASS_G3_DN 5132All SZGR genes in this pathway
CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_DN 17997All SZGR genes in this pathway
WOO_LIVER_CANCER_RECURRENCE_DN 8054All SZGR genes in this pathway
GYORFFY_DOXORUBICIN_RESISTANCE 5634All SZGR genes in this pathway
HOSHIDA_LIVER_CANCER_SUBCLASS_S3 266180All SZGR genes in this pathway
CAIRO_LIVER_DEVELOPMENT_DN 222141All SZGR genes in this pathway
BAE_BRCA1_TARGETS_DN 3227All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_LATE 1137655All SZGR genes in this pathway
LEE_BMP2_TARGETS_UP 745475All SZGR genes in this pathway
FEVR_CTNNB1_TARGETS_UP 682433All SZGR genes in this pathway


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