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| GeneID |
1645
|
| Symbol |
AKR1C1
|
| Synonyms |
2-ALPHA-HSD|20-ALPHA-HSD|C9|DD1|DDH|DDH1|H-37|HAKRC|MBAB|MGC8954
|
| Description |
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) |
| See related |
HGNC:384|MIM:600449|Ensembl:ENSG00000187134|HPRD:07194| |
| Locus tag |
RP11-69D4.1 |
| Gene type |
protein-coding |
| Map location |
10p15-p14 |
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| Gene set name |
Method of gene set |
Evidence |
Info |
| Expression | Expression | P value: 1.747 | |
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| General Gene Expression (microarray) ? |
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| Gene Expression in Brain Regions (new) |
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| Top co-expressed genes in Brain Regions (new) |
|
| Gene | Pearson's Correlation | Spearman's Correlation | | |
| Top 10 positively co-expressed genes |
| ATG2B | 0.96 | 0.96 | | |
| UBR3 | 0.95 | 0.95 | | |
| DMXL2 | 0.94 | 0.93 | | |
| NF1 | 0.94 | 0.96 | | |
| AKAP11 | 0.93 | 0.93 | | |
| VPS13D | 0.93 | 0.93 | | |
| HIPK3 | 0.93 | 0.95 | | |
| GARNL1 | 0.93 | 0.94 | | |
| CPD | 0.93 | 0.91 | | |
| COL4A3BP | 0.92 | 0.92 | | |
Top 10 negatively co-expressed genes | | C1orf61 | -0.55 | -0.70 | | |
| ENHO | -0.54 | -0.63 | | |
| AF347015.21 | -0.54 | -0.55 | | |
| C1orf54 | -0.53 | -0.63 | | |
| HIGD1B | -0.52 | -0.57 | | |
| FXYD1 | -0.52 | -0.55 | | |
| PLA2G5 | -0.51 | -0.54 | | |
| EIF4EBP3 | -0.51 | -0.56 | | |
| VAMP5 | -0.50 | -0.53 | | |
| MT-CO2 | -0.50 | -0.55 | | |
|
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0004033 | aldo-keto reductase activity | TAS | | 7789999 |
| GO:0016491 | oxidoreductase activity | IEA | | - |
| GO:0032052 | bile acid binding | IDA | | 8486699 |
| GO:0047042 | 3-alpha-hydroxysteroid dehydrogenase (B-specific) activity | IDA | | 8486699 |
| GO:0047115 | trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity | IDA | | 8486699 |
| GO:0047006 | 20-alpha-hydroxysteroid dehydrogenase activity | IEA | | - |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0008206 | bile acid metabolic process | IDA | | 8486699 |
| GO:0007586 | digestion | IDA | | 8486699 |
| GO:0015721 | bile acid and bile salt transport | TAS | | 8486699 |
| GO:0006805 | xenobiotic metabolic process | NAS | | 8486699 |
| GO:0051260 | protein homooligomerization | IDA | | 8486699 |
| GO:0030299 | cholesterol absorption | TAS | | 8486699 |
| GO:0042632 | cholesterol homeostasis | TAS | | 8486699 |
| GO:0055114 | oxidation reduction | IDA | | 8486699 |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0005829 | cytosol | IDA | | 8486699 |
| GO:0005737 | cytoplasm | IEA | | - |
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