Gene Page: DDOST

Summary
GeneID  1650
Symbol  DDOST
Synonyms  AGE-R1|KIAA0115|MGC2191|OK/SW-cl.45|OST|OST48|WBP1
Description  dolichyl-diphosphooligosaccharide-protein glycosyltransferase
See related  HGNC:2728|MIM:602202|Ensembl:ENSG00000117242|HPRD:03728|
Locus tag  -
Gene type  protein-coding
Map location  1p36.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.043 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
CUL30.920.92
SNAPC30.900.90
PRPF180.890.88
YME1L10.890.90
SKIV2L20.890.89
MSH20.890.89
GPBP10.880.87
GGNBP20.880.89
FIP1L10.880.85
SMNDC10.880.85
Top 10 negatively co-expressed genes
AF347015.31-0.73-0.76
MT-CO2-0.72-0.74
HIGD1B-0.72-0.77
AF347015.33-0.71-0.72
AF347015.2-0.70-0.71
AF347015.8-0.70-0.72
MT-CYB-0.70-0.72
IFI27-0.70-0.77
FXYD1-0.70-0.74
AF347015.15-0.68-0.71
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004579dolichyl-diphosphooligosaccharide-protein glycotransferase activityIDA9642163 
GO:0005515protein bindingIPI17353931 
GO:0016740transferase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006496protein amino acid terminal N-glycosylationIDA9642163 
GO:0034097response to cytokine stimulusIDA9642163 
GO:0018279protein amino acid N-linked glycosylation via asparagineIC15835887 
GO:0042110T cell activationIDA9642163 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005792microsomeIDA9642163 
GO:0005783endoplasmic reticulumIEA-
GO:0016020membraneIEA-
GO:0016021integral to membraneIEA-
GO:0008250oligosaccharyltransferase complexTAS15835887 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
GSTK1GST13glutathione S-transferase kappa 1Affinity Capture-MSBioGRID17353931 
MAGEA6MAGE-3b | MAGE3B | MAGE6 | MGC52297melanoma antigen family A, 6Affinity Capture-MSBioGRID17353931 
PGRMC1HPR6.6 | MPRprogesterone receptor membrane component 1Affinity Capture-MSBioGRID17353931 
RFXANKANKRA1 | BLS | F14150_1 | MGC138628 | RFX-Bregulatory factor X-associated ankyrin-containing proteinAffinity Capture-MSBioGRID17353931 
SAP182HOR0202 | MGC27131 | SAP18pSin3A-associated protein, 18kDaAffinity Capture-MSBioGRID17353931 
TMBIM4CGI-119 | GAAP | S1R | ZPROtransmembrane BAX inhibitor motif containing 4Affinity Capture-MSBioGRID17353931 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_N_GLYCAN_BIOSYNTHESIS 4631All SZGR genes in this pathway
REACTOME_TRANSLATION 22275All SZGR genes in this pathway
REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE 17953All SZGR genes in this pathway
REACTOME_METABOLISM_OF_PROTEINS 518242All SZGR genes in this pathway
REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION 188116All SZGR genes in this pathway
REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION 8154All SZGR genes in this pathway
REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING 1311All SZGR genes in this pathway
REACTOME_INNATE_IMMUNE_SYSTEM 279178All SZGR genes in this pathway
REACTOME_IMMUNE_SYSTEM 933616All SZGR genes in this pathway
ONKEN_UVEAL_MELANOMA_DN 526357All SZGR genes in this pathway
BORCZUK_MALIGNANT_MESOTHELIOMA_UP 305185All SZGR genes in this pathway
MAYBURD_RESPONSE_TO_L663536_DN 5632All SZGR genes in this pathway
LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_DN 800473All SZGR genes in this pathway
LI_AMPLIFIED_IN_LUNG_CANCER 178108All SZGR genes in this pathway
PATIL_LIVER_CANCER 747453All SZGR genes in this pathway
DAIRKEE_TERT_TARGETS_UP 380213All SZGR genes in this pathway
SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_DN 584395All SZGR genes in this pathway
LIU_NASOPHARYNGEAL_CARCINOMA 7038All SZGR genes in this pathway
LIAO_METASTASIS 539324All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN 514330All SZGR genes in this pathway
GOTZMANN_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_DN 206136All SZGR genes in this pathway
MORI_PLASMA_CELL_UP 5129All SZGR genes in this pathway
TARTE_PLASMA_CELL_VS_B_LYMPHOCYTE_UP 7851All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_CIS 12877All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN 546351All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP 555346All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
WELCSH_BRCA1_TARGETS_UP 198132All SZGR genes in this pathway
MARSON_BOUND_BY_E2F4_UNSTIMULATED 728415All SZGR genes in this pathway
GRADE_COLON_CANCER_UP 871505All SZGR genes in this pathway
QI_PLASMACYTOMA_DN 10063All SZGR genes in this pathway
CHAUHAN_RESPONSE_TO_METHOXYESTRADIOL_DN 10265All SZGR genes in this pathway
NUTT_GBM_VS_AO_GLIOMA_UP 4634All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_DN 366257All SZGR genes in this pathway
MILI_PSEUDOPODIA_CHEMOTAXIS_DN 457302All SZGR genes in this pathway
MILI_PSEUDOPODIA_HAPTOTAXIS_DN 668419All SZGR genes in this pathway
BOYAULT_LIVER_CANCER_SUBCLASS_G23_UP 5235All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_CLASSES_UP 605377All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_17 181101All SZGR genes in this pathway
KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP 756494All SZGR genes in this pathway
KIM_ALL_DISORDERS_CALB1_CORR_UP 548370All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_3_UP 430288All SZGR genes in this pathway


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