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|
| GeneID |
1777
|
| Symbol |
DNASE2
|
| Synonyms |
DNASE2A|DNL|DNL2
|
| Description |
deoxyribonuclease II, lysosomal |
| See related |
HGNC:2960|MIM:126350|Ensembl:ENSG00000105612|HPRD:00531| |
| Locus tag |
- |
| Gene type |
protein-coding |
| Map location |
19p13.2 |
|
| |
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|
| Gene set name |
Method of gene set |
Evidence |
Info |
| Expression | Expression | P value: 1.369 | |
|
| |
| General Gene Expression (microarray) ? |
|
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| |
| Gene Expression in Brain Regions (new) |
|
| |
| Top co-expressed genes in Brain Regions (new) |
|
| Gene | Pearson's Correlation | Spearman's Correlation | | |
| Top 10 positively co-expressed genes |
| IGDCC3 | 0.93 | 0.87 | | |
| KIAA1305 | 0.91 | 0.90 | | |
| ADAMTS7 | 0.91 | 0.84 | | |
| NINL | 0.90 | 0.90 | | |
| DCHS1 | 0.89 | 0.88 | | |
| PLXNA3 | 0.89 | 0.90 | | |
| LPAR2 | 0.89 | 0.86 | | |
| QRICH2 | 0.89 | 0.84 | | |
| PLEKHG2 | 0.88 | 0.86 | | |
| PLXNB2 | 0.88 | 0.89 | | |
Top 10 negatively co-expressed genes | | HLA-F | -0.63 | -0.71 | | |
| FBXO2 | -0.63 | -0.66 | | |
| ALDOC | -0.62 | -0.66 | | |
| C5orf53 | -0.62 | -0.74 | | |
| AIFM3 | -0.62 | -0.68 | | |
| LHPP | -0.61 | -0.59 | | |
| LDHD | -0.60 | -0.61 | | |
| PTH1R | -0.60 | -0.66 | | |
| S100B | -0.60 | -0.76 | | |
| CLU | -0.60 | -0.64 | | |
|
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0005179 | hormone activity | IEA | | - |
| GO:0004531 | deoxyribonuclease II activity | TAS | | 9714827 |
| GO:0003677 | DNA binding | TAS | | 9714827 |
| GO:0005515 | protein binding | IPI | | 17353931 |
| GO:0004519 | endonuclease activity | IEA | | - |
| GO:0016787 | hydrolase activity | IEA | | - |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0006308 | DNA catabolic process | IEA | | - |
| GO:0006915 | apoptosis | IEA | | - |
| GO:0007275 | multicellular organismal development | IEA | | - |
| GO:0030218 | erythrocyte differentiation | IEA | | - |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0005576 | extracellular region | IEA | | - |
| GO:0005764 | lysosome | TAS | | 9714827 |
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- SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
- Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.
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