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| GeneID |
1816
|
| Symbol |
DRD5
|
| Synonyms |
DBDR|DRD1B|DRD1L2|MGC10601
|
| Description |
dopamine receptor D5 |
| See related |
HGNC:3026|MIM:126453|Ensembl:ENSG00000169676|HPRD:00542| |
| Locus tag |
- |
| Gene type |
protein-coding |
| Map location |
4p16.1 |
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| General Gene Expression (microarray) ? |
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| Gene Expression in Brain Regions (new) |
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| Top co-expressed genes in Brain Regions (new) |
|
| Gene | Pearson's Correlation | Spearman's Correlation | | |
| Top 10 positively co-expressed genes |
| AC110491.1 | 0.60 | 0.47 | | |
| CRYBG3 | 0.60 | 0.51 | | |
| CFTR | 0.58 | 0.45 | | |
| DLC1 | 0.57 | 0.46 | | |
| RHOQ | 0.56 | 0.44 | | |
| ANO3 | 0.55 | 0.45 | | |
| SLC1A2 | 0.55 | 0.39 | | |
| TJP1 | 0.54 | 0.52 | | |
| SCN4B | 0.54 | 0.42 | | |
| ITGAV | 0.54 | 0.43 | | |
Top 10 negatively co-expressed genes | | RPL35 | -0.31 | -0.41 | | |
| RPL36 | -0.30 | -0.41 | | |
| RPS7 | -0.29 | -0.34 | | |
| PFDN5 | -0.29 | -0.34 | | |
| BCL7C | -0.29 | -0.37 | | |
| RPLP1 | -0.28 | -0.37 | | |
| RPS14 | -0.28 | -0.34 | | |
| FAU | -0.28 | -0.36 | | |
| RPL31 | -0.28 | -0.35 | | |
| SCNM1 | -0.28 | -0.30 | | |
|
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0001588 | dopamine receptor coupled via Gs | TAS | Neurotransmitter, dopamine (GO term level: 9) | 9457173 |
| GO:0004872 | receptor activity | IEA | | - |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0060158 | dopamine receptor, phospholipase C activating pathway | TAS | dopamine (GO term level: 10) | 9457173 |
| GO:0007268 | synaptic transmission | NAS | neuron, Synap, Neurotransmitter (GO term level: 6) | 7727453 |
| GO:0007191 | dopamine receptor, adenylate cyclase activating pathway | IDA | dopamine (GO term level: 12) | 1826762 |
| GO:0001963 | synaptic transmission, dopaminergic | NAS | neuron, Synap, Neurotransmitter, dopamine (GO term level: 8) | 11036203 |
| GO:0007190 | activation of adenylate cyclase activity | TAS | | 9457173 |
| GO:0007186 | G-protein coupled receptor protein signaling pathway | IEA | | - |
| GO:0007165 | signal transduction | IEA | | - |
| GO:0006800 | oxygen and reactive oxygen species metabolic process | IDA | | 16352863 |
| GO:0006874 | cellular calcium ion homeostasis | TAS | | 9457173 |
| GO:0033861 | negative regulation of NAD(P)H oxidase activity | IDA | | 16352863 |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0005886 | plasma membrane | IDA | | 10531415 |11500503 |
| GO:0005887 | integral to plasma membrane | NAS | | 1826762 |
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