Gene Page: EEF2

Summary
GeneID  1938
Symbol  EEF2
Synonyms  EEF-2|EF2
Description  eukaryotic translation elongation factor 2
See related  HGNC:3214|MIM:130610|Ensembl:ENSG00000167658|HPRD:00561|
Locus tag  -
Gene type  protein-coding
Map location  19pter-q12
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.5959 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ZMIZ10.970.96
RAD54L20.960.94
CREBBP0.960.96
SETD1B0.960.96
CRAMP1L0.960.96
KIAA15490.960.97
IGF1R0.960.94
BCL90.960.97
KDM6B0.950.92
XKR70.950.96
Top 10 negatively co-expressed genes
SERPINB6-0.66-0.77
C5orf53-0.66-0.79
AIFM3-0.64-0.77
S100B-0.64-0.87
AF347015.31-0.64-0.92
HEPN1-0.64-0.75
HLA-F-0.64-0.75
AF347015.27-0.63-0.89
TSC22D4-0.63-0.79
ALDOC-0.63-0.70
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0003746translation elongation factor activityIEA-
GO:0003924GTPase activityIEA-
GO:0005515protein bindingIPI17220478 
GO:0005525GTP bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006414translational elongationEXP15189156 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005737cytoplasmIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
TP53FLJ92943 | LFS1 | TRP53 | p53tumor protein p53-HPRD,BioGRID12891704 
TRPM7CHAK | CHAK1 | FLJ20117 | FLJ25718 | LTRPC7 | TRP-PLIKtransient receptor potential cation channel, subfamily M, member 7-HPRD14594813 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
BIOCARTA_EIF_PATHWAY 169All SZGR genes in this pathway
PID_MTOR_4PATHWAY 6955All SZGR genes in this pathway
REACTOME_TRANSLATION 22275All SZGR genes in this pathway
REACTOME_PEPTIDE_CHAIN_ELONGATION 15341All SZGR genes in this pathway
REACTOME_METABOLISM_OF_PROTEINS 518242All SZGR genes in this pathway
PARENT_MTOR_SIGNALING_UP 567375All SZGR genes in this pathway
TIEN_INTESTINE_PROBIOTICS_24HR_DN 214133All SZGR genes in this pathway
PEREZ_TP53_TARGETS 1174695All SZGR genes in this pathway
DIRMEIER_LMP1_RESPONSE_EARLY 6648All SZGR genes in this pathway
GRUETZMANN_PANCREATIC_CANCER_DN 203134All SZGR genes in this pathway
TOMLINS_PROSTATE_CANCER_UP 4027All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
LOPEZ_MBD_TARGETS 957597All SZGR genes in this pathway
BENPORATH_NANOG_TARGETS 988594All SZGR genes in this pathway
BENPORATH_SOX2_TARGETS 734436All SZGR genes in this pathway
BENPORATH_EED_TARGETS 1062725All SZGR genes in this pathway
KUROKAWA_LIVER_CANCER_CHEMOTHERAPY_DN 4128All SZGR genes in this pathway
ZHOU_TNF_SIGNALING_4HR 5436All SZGR genes in this pathway
HU_GENOTOXIC_DAMAGE_24HR 3522All SZGR genes in this pathway
SIMBULAN_PARP1_TARGETS_UP 3123All SZGR genes in this pathway
GERHOLD_ADIPOGENESIS_DN 6444All SZGR genes in this pathway
LEE_AGING_NEOCORTEX_UP 8959All SZGR genes in this pathway
ZHOU_TNF_SIGNALING_30MIN 5436All SZGR genes in this pathway
LEE_CALORIE_RESTRICTION_NEOCORTEX_DN 8858All SZGR genes in this pathway
ZAMORA_NOS2_TARGETS_DN 9671All SZGR genes in this pathway
JIANG_AGING_CEREBRAL_CORTEX_DN 5443All SZGR genes in this pathway
ZHONG_SECRETOME_OF_LUNG_CANCER_AND_ENDOTHELIUM 6647All SZGR genes in this pathway
ZHONG_SECRETOME_OF_LUNG_CANCER_AND_FIBROBLAST 13293All SZGR genes in this pathway
HILLION_HMGA1_TARGETS 9071All SZGR genes in this pathway
LEIN_OLIGODENDROCYTE_MARKERS 7453All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_UNSTIMULATED 1229713All SZGR genes in this pathway
SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_DN 154101All SZGR genes in this pathway
ACEVEDO_NORMAL_TISSUE_ADJACENT_TO_LIVER_TUMOR_DN 354216All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_DN 540340All SZGR genes in this pathway
GRADE_COLON_CANCER_UP 871505All SZGR genes in this pathway
BHATI_G2M_ARREST_BY_2METHOXYESTRADIOL_DN 12775All SZGR genes in this pathway
CHNG_MULTIPLE_MYELOMA_HYPERPLOID_UP 5225All SZGR genes in this pathway
MALONEY_RESPONSE_TO_17AAG_UP 4126All SZGR genes in this pathway
BLUM_RESPONSE_TO_SALIRASIB_UP 245159All SZGR genes in this pathway
JIANG_TIP30_TARGETS_UP 4628All SZGR genes in this pathway
FLOTHO_PEDIATRIC_ALL_THERAPY_RESPONSE_UP 5333All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
SWEET_LUNG_CANCER_KRAS_UP 491316All SZGR genes in this pathway
SWEET_KRAS_ONCOGENIC_SIGNATURE 8956All SZGR genes in this pathway
HOFFMANN_PRE_BI_TO_LARGE_PRE_BII_LYMPHOCYTE_DN 7561All SZGR genes in this pathway
HOFFMANN_LARGE_TO_SMALL_PRE_BII_LYMPHOCYTE_DN 7247All SZGR genes in this pathway
HSIAO_HOUSEKEEPING_GENES 389245All SZGR genes in this pathway
IRITANI_MAD1_TARGETS_DN 4730All SZGR genes in this pathway
JISON_SICKLE_CELL_DISEASE_DN 18197All SZGR genes in this pathway
WONG_EMBRYONIC_STEM_CELL_CORE 335193All SZGR genes in this pathway
KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP 756494All SZGR genes in this pathway
KIM_ALL_DISORDERS_CALB1_CORR_UP 548370All SZGR genes in this pathway
BILANGES_SERUM_AND_RAPAMYCIN_SENSITIVE_GENES 6835All SZGR genes in this pathway
PURBEY_TARGETS_OF_CTBP1_AND_SATB1_UP 8752All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_8D 882506All SZGR genes in this pathway


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.