Gene Page: EGR4

Summary
GeneID  1961
Symbol  EGR4
Synonyms  NGFI-C|NGFIC|PAT133
Description  early growth response 4
See related  HGNC:3241|MIM:128992|Ensembl:ENSG00000135625|HPRD:00550|
Locus tag  -
Gene type  protein-coding
Map location  2p13
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
ExpressionExpressionP value: 1.547 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003700transcription factor activityNAS1584812 
GO:0008270zinc ion bindingIEA-
GO:0046872metal ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006355regulation of transcription, DNA-dependentIEA-
GO:0006350transcriptionIEA-
GO:0008284positive regulation of cell proliferationTAS1658795 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005622intracellularIEA-
GO:0005634nucleusIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
NFATC2KIAA0611 | NFAT1 | NFATPnuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2-HPRD12560487 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS 4535All SZGR genes in this pathway
PID_NFAT_TFPATHWAY 4739All SZGR genes in this pathway
PID_CD8_TCR_DOWNSTREAM_PATHWAY 6556All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP 485293All SZGR genes in this pathway
NAGASHIMA_NRG1_SIGNALING_UP 176123All SZGR genes in this pathway
NAGASHIMA_EGF_SIGNALING_UP 5840All SZGR genes in this pathway
PEREZ_TP63_TARGETS 355243All SZGR genes in this pathway
BENPORATH_SUZ12_TARGETS 1038678All SZGR genes in this pathway
BENPORATH_EED_TARGETS 1062725All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3 1118744All SZGR genes in this pathway
BENPORATH_PRC2_TARGETS 652441All SZGR genes in this pathway
SHEN_SMARCA2_TARGETS_DN 357212All SZGR genes in this pathway
SATO_SILENCED_BY_DEACETYLATION_IN_PANCREATIC_CANCER 5030All SZGR genes in this pathway
HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP 461298All SZGR genes in this pathway
HUANG_FOXA2_TARGETS_UP 4528All SZGR genes in this pathway
MITSIADES_RESPONSE_TO_APLIDIN_UP 439257All SZGR genes in this pathway
MATZUK_SPERMATOCYTE 7255All SZGR genes in this pathway
MATZUK_SPERMATOZOA 11477All SZGR genes in this pathway
LIN_NPAS4_TARGETS_DN 6848All SZGR genes in this pathway
HUNSBERGER_EXERCISE_REGULATED_GENES 3126All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3 142103All SZGR genes in this pathway
MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3 1069729All SZGR genes in this pathway
MIKKELSEN_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3 210148All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_2ND_EGF_PULSE_ONLY 1725838All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-3263243311A,m8hsa-miR-326CCUCUGGGCCCUUCCUCCAG
miR-330414420m8hsa-miR-330brainGCAAAGCACACGGCCUGCAGAGA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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