Gene Page: AIF1

Summary
GeneID  199
Symbol  AIF1
Synonyms  AIF-1|IBA1|IRT-1
Description  allograft inflammatory factor 1
See related  HGNC:352|MIM:601833|Ensembl:ENSG00000204472|HPRD:03496|
Locus tag  DADB-70P7.8
Gene type  protein-coding
Map location  6p21.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.033 
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
RBM470.700.40
F50.680.41
PRLR0.680.38
CP0.670.43
KCNJ130.660.30
SLC5A50.660.29
ABCA40.650.32
CLIC60.650.37
SLC13A40.630.23
FOLR10.610.27
Top 10 negatively co-expressed genes
RPL35-0.34-0.52
RPS7-0.32-0.48
RPL27-0.32-0.48
FAU-0.32-0.46
RPS10-0.32-0.45
RPL31-0.31-0.49
PFDN5-0.31-0.47
UXT-0.31-0.45
ALKBH7-0.30-0.44
C22orf32-0.30-0.46
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003674molecular_functionND-
GO:0005509calcium ion bindingIEA-
GO:0005515protein bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006950response to stressTAS9614071 
GO:0007050cell cycle arrestTAS9614071 
GO:0008285negative regulation of cell proliferationTAS9614071 
GO:0008150biological_processND-
GO:0006954inflammatory responseTAS8912632 
GO:0051017actin filament bundle formationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0001726ruffleIEA-
GO:0001891phagocytic cupIEA-
GO:0005575cellular_componentND-
GO:0005634nucleusTAS9614071 
GO:0005737cytoplasmIEA-
GO:0005884actin filamentIEA-
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
GAZDA_DIAMOND_BLACKFAN_ANEMIA_ERYTHROID_DN 493298All SZGR genes in this pathway
FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_DN 463290All SZGR genes in this pathway
THUM_SYSTOLIC_HEART_FAILURE_UP 423283All SZGR genes in this pathway
GRAHAM_CML_QUIESCENT_VS_NORMAL_QUIESCENT_DN 4732All SZGR genes in this pathway
GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_DN 126All SZGR genes in this pathway
LINDGREN_BLADDER_CANCER_CLUSTER_2B 392251All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_UP 8758All SZGR genes in this pathway
PEART_HDAC_PROLIFERATION_CLUSTER_DN 7657All SZGR genes in this pathway
BASSO_CD40_SIGNALING_DN 6844All SZGR genes in this pathway
YAGI_AML_FAB_MARKERS 191131All SZGR genes in this pathway
ZHAN_MULTIPLE_MYELOMA_DN 4127All SZGR genes in this pathway
KAYO_AGING_MUSCLE_UP 244165All SZGR genes in this pathway
BAELDE_DIABETIC_NEPHROPATHY_DN 434302All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_DN 911527All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_DN 1011592All SZGR genes in this pathway
COATES_MACROPHAGE_M1_VS_M2_UP 8152All SZGR genes in this pathway
SMID_BREAST_CANCER_NORMAL_LIKE_UP 476285All SZGR genes in this pathway
BASSO_HAIRY_CELL_LEUKEMIA_DN 8066All SZGR genes in this pathway
ICHIBA_GRAFT_VERSUS_HOST_DISEASE_35D_UP 13179All SZGR genes in this pathway
WUNDER_INFLAMMATORY_RESPONSE_AND_CHOLESTEROL_UP 5838All SZGR genes in this pathway
RAY_TARGETS_OF_P210_BCR_ABL_FUSION_DN 1611All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_DN 315201All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_HGF_DN 235144All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_UP 408276All SZGR genes in this pathway
LEE_RECENT_THYMIC_EMIGRANT 227128All SZGR genes in this pathway
LEE_DIFFERENTIATING_T_LYMPHOCYTE 200115All SZGR genes in this pathway
CHEN_METABOLIC_SYNDROM_NETWORK 1210725All SZGR genes in this pathway
POOLA_INVASIVE_BREAST_CANCER_UP 288168All SZGR genes in this pathway
YAGI_AML_WITH_T_8_21_TRANSLOCATION 368247All SZGR genes in this pathway
HOSHIDA_LIVER_CANCER_SUBCLASS_S1 237159All SZGR genes in this pathway
NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_UP 7646All SZGR genes in this pathway
NIELSEN_SYNOVIAL_SARCOMA_DN 2013All SZGR genes in this pathway
ACOSTA_PROLIFERATION_INDEPENDENT_MYC_TARGETS_DN 11674All SZGR genes in this pathway
KIM_GLIS2_TARGETS_UP 8461All SZGR genes in this pathway


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