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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

Gene Ranking Integration

Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: CRTC2

Summary

GeneID

200186

Symbol

CRTC2

Synonyms

RP11-422P24.6|TORC2

Description

CREB regulated transcription coactivator 2

Locus tag

Gene type

protein-coding

Map location

1q21.3

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GSMA_I

genome scan meta-analysis

Psr: 0.0235

GSMA_IIA

genome scan meta-analysis (All samples)

Psr: 0.00814

Network

Shortest path distance of core genes in the Human protein-protein interaction network

Contribution to shortest path in PPI network: 0.0147

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006355

regulation of transcription, DNA-dependent

IEA

GO:0006350

transcription

IEA

GO:0044419

interspecies interaction between organisms

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005634

nucleus

IEA

GO:0005737

cytoplasm

IEA

Interactions

Shown by Network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
PPP3CA	CALN \| CALNA \| CALNA1 \| CCN1 \| CNA1 \| PPP2B	protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform	TORC2 interacts with CnA.	BIND	15454081
SNF1LK2	DKFZp434K1115 \| KIAA0781 \| LOH11CR1I \| QIK \| SIK2	SNF1-like kinase 2	TORC2 interacts with SIK2.	BIND	15454081
SNF1LK2	DKFZp434K1115 \| KIAA0781 \| LOH11CR1I \| QIK \| SIK2	SNF1-like kinase 2	-	HPRD,BioGRID	15454081
YWHAB	GW128 \| HS1 \| KCIP-1	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	TORC2 interacts with 14-3-3-beta.	BIND	15454081
YWHAG	14-3-3GAMMA	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	Affinity Capture-MS	BioGRID	17353931
YWHAG	14-3-3GAMMA		-	HPRD	15324660
YWHAQ	14-3-3 \| 1C5 \| HS1	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	Affinity Capture-MS Affinity Capture-Western	BioGRID	15454081 \|17353931

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-149	369	376	1A,m8	hsa-miR-149^brain	UCUGGCUCCGUGUCUUCACUCC
miR-369-3p	404	410	1A	hsa-miR-369-3p	AAUAAUACAUGGUUGAUCUUU
miR-374	404	410	m8	hsa-miR-374	UUAUAAUACAACCUGAUAAGUG
miR-93.hd/291-3p/294/295/302/372/373/520	218	224	m8	hsa-miR-93^brain	AAAGUGCUGUUCGUGCAGGUAG
				hsa-miR-302a	UAAGUGCUUCCAUGUUUUGGUGA
				hsa-miR-302b	UAAGUGCUUCCAUGUUUUAGUAG
				hsa-miR-302c	UAAGUGCUUCCAUGUUUCAGUGG
				hsa-miR-302d	UAAGUGCUUCCAUGUUUGAGUGU
				hsa-miR-372	AAAGUGCUGCGACAUUUGAGCGU
				hsa-miR-373	GAAGUGCUUCGAUUUUGGGGUGU
				hsa-miR-520e	AAAGUGCUUCCUUUUUGAGGG
				hsa-miR-520a	AAAGUGCUUCCCUUUGGACUGU
				hsa-miR-520b	AAAGUGCUUCCUUUUAGAGGG
				hsa-miR-520c	AAAGUGCUUCCUUUUAGAGGGUU
				hsa-miR-520d	AAAGUGCUUCUCUUUGGUGGGUU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.