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GeneID |
2019
|
Symbol |
EN1
|
Synonyms |
-
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Description |
engrailed homeobox 1 |
See related |
HGNC:3342|MIM:131290|Ensembl:ENSG00000163064|HPRD:08835| |
Locus tag |
- |
Gene type |
protein-coding |
Map location |
2q13-q21 |
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Gene set name |
Method of gene set |
Evidence |
Info |
GSMA_I | genome scan meta-analysis | Psr: 0.0004 | | GSMA_IIA | genome scan meta-analysis (All samples) | Psr: 0.00755 | | Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia] | Click to show detail | GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 4 | |
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General Gene Expression (microarray) ? |
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Gene Expression in Brain Regions (new) |
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Top co-expressed genes in Brain Regions (new) |
|
Gene | Pearson's Correlation | Spearman's Correlation | | |
Top 10 positively co-expressed genes |
ABCB1 | 0.87 | 0.88 | | |
TPCN1 | 0.86 | 0.89 | | |
KANK1 | 0.86 | 0.87 | | |
ATP1A2 | 0.86 | 0.87 | | |
SFXN5 | 0.86 | 0.84 | | |
GPR37L1 | 0.85 | 0.83 | | |
SEMA3G | 0.85 | 0.85 | | |
NACC2 | 0.85 | 0.91 | | |
SLC6A12 | 0.85 | 0.90 | | |
PRELP | 0.84 | 0.90 | | |
Top 10 negatively co-expressed genes | POLB | -0.67 | -0.77 | | |
MED19 | -0.67 | -0.72 | | |
FRG1 | -0.66 | -0.79 | | |
TRNAU1AP | -0.66 | -0.73 | | |
OCIAD2 | -0.66 | -0.73 | | |
ING4 | -0.65 | -0.70 | | |
DUSP12 | -0.65 | -0.68 | | |
ALKBH2 | -0.65 | -0.75 | | |
COMMD3 | -0.65 | -0.76 | | |
NR2C2AP | -0.64 | -0.72 | | |
|
Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0003700 | transcription factor activity | IEA | | - |
GO:0005249 | voltage-gated potassium channel activity | IEA | | - |
GO:0043565 | sequence-specific DNA binding | IEA | | - |
Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0048666 | neuron development | IEA | neuron (GO term level: 9) | - |
GO:0030917 | midbrain-hindbrain boundary development | IEA | Brain (GO term level: 10) | - |
GO:0030902 | hindbrain development | IEA | Brain (GO term level: 8) | - |
GO:0030901 | midbrain development | IEA | Brain (GO term level: 8) | - |
GO:0001501 | skeletal system development | TAS | | 8684466 |
GO:0006355 | regulation of transcription, DNA-dependent | IEA | | - |
GO:0009954 | proximal/distal pattern formation | IEA | | - |
GO:0009953 | dorsal/ventral pattern formation | IEA | | - |
GO:0009653 | anatomical structure morphogenesis | TAS | | 8094370 |
GO:0006813 | potassium ion transport | IEA | | - |
GO:0007275 | multicellular organismal development | IEA | | - |
GO:0043473 | pigmentation | IEA | | - |
GO:0035115 | embryonic forelimb morphogenesis | IEA | | - |
Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0005634 | nucleus | IEA | | - |
GO:0008076 | voltage-gated potassium channel complex | IEA | | - |
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- SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
- Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.
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