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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Gene Page: HIPK1

Summary

GeneID

204851

Symbol

HIPK1

Synonyms

KIAA0630|MGC26642|MGC33446|MGC33548|Myak|Nbak2

Description

homeodomain interacting protein kinase 1

Locus tag

Gene type

protein-coding

Map location

1p13.2

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GSMA_I

genome scan meta-analysis

Psr: 0.0235

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0000166

nucleotide binding

IEA

GO:0003677

DNA binding

IEA

GO:0005515

protein binding

IPI

12529400 |12702766

GO:0005524

ATP binding

IEA

GO:0004674

protein serine/threonine kinase activity

IEA

GO:0016740

transferase activity

IEA

GO:0016301

kinase activity

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006355

regulation of transcription, DNA-dependent

IEA

GO:0006350

transcription

IEA

GO:0006468

protein amino acid phosphorylation

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005634

nucleus

IEA

GO:0005737

cytoplasm

IEA

Interactions

Shown by Network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
DAXX	BING2 \| DAP6 \| EAP1 \| MGC126245 \| MGC126246	death-domain associated protein	-	HPRD,BioGRID	12529400
HOXD4	HHO.C13 \| HOX-5.1 \| HOX4 \| HOX4B \| Hox-4.2	homeobox D4	-	HPRD	9748262
NKX2-5	CHNG5 \| CSX \| CSX1 \| NKX2.5 \| NKX2E \| NKX4-1	NK2 transcription factor related, locus 5 (Drosophila)	-	HPRD	9748262
TP53	FLJ92943 \| LFS1 \| TRP53 \| p53	tumor protein p53	-	HPRD,BioGRID	12702766

Pathway annotation

Pathway name	Pathway size	# SZGR genes in pathway	Info
PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_DN	136	86	All SZGR genes in this pathway
WATANABE_RECTAL_CANCER_RADIOTHERAPY_RESPONSIVE_UP	108	67	All SZGR genes in this pathway
FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_DN	463	290	All SZGR genes in this pathway
BORCZUK_MALIGNANT_MESOTHELIOMA_UP	305	185	All SZGR genes in this pathway
OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP	233	161	All SZGR genes in this pathway
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_DN	205	127	All SZGR genes in this pathway
KIM_WT1_TARGETS_8HR_UP	164	122	All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_UP	1821	933	All SZGR genes in this pathway
SCHLOSSER_SERUM_RESPONSE_DN	712	443	All SZGR genes in this pathway
MOHANKUMAR_TLX1_TARGETS_UP	414	287	All SZGR genes in this pathway
SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM1	229	137	All SZGR genes in this pathway
NUYTTEN_NIPP1_TARGETS_DN	848	527	All SZGR genes in this pathway
PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_UP	283	177	All SZGR genes in this pathway
SHEN_SMARCA2_TARGETS_UP	424	268	All SZGR genes in this pathway
BYSTROEM_CORRELATED_WITH_IL5_DN	64	47	All SZGR genes in this pathway
FLECHNER_PBL_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP	151	100	All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN	546	351	All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP	555	346	All SZGR genes in this pathway
ZHANG_TARGETS_OF_EWSR1_FLI1_FUSION	88	68	All SZGR genes in this pathway
GERY_CEBP_TARGETS	126	90	All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_14HR_UP	156	101	All SZGR genes in this pathway
MONNIER_POSTRADIATION_TUMOR_ESCAPE_UP	393	244	All SZGR genes in this pathway
GAVIN_FOXP3_TARGETS_CLUSTER_T4	94	69	All SZGR genes in this pathway
SANSOM_APC_MYC_TARGETS	217	138	All SZGR genes in this pathway
FINETTI_BREAST_CANCERS_KINOME_GRAY	15	10	All SZGR genes in this pathway
FUJII_YBX1_TARGETS_DN	202	132	All SZGR genes in this pathway
NUTT_GBM_VS_AO_GLIOMA_UP	46	34	All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_2_DN	336	211	All SZGR genes in this pathway
MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_UP	259	159	All SZGR genes in this pathway
BAKKER_FOXO3_TARGETS_UP	61	41	All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_8D	882	506	All SZGR genes in this pathway
FORTSCHEGGER_PHF8_TARGETS_DN	784	464	All SZGR genes in this pathway
BOSCO_ALLERGEN_INDUCED_TH2_ASSOCIATED_MODULE	151	86	All SZGR genes in this pathway
ROESSLER_LIVER_CANCER_METASTASIS_DN	53	29	All SZGR genes in this pathway

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-101	1488	1494	1A	hsa-miR-101	UACAGUACUGUGAUAACUGAAG
miR-124.1	1671	1677	m8	hsa-miR-124a	UUAAGGCACGCGGUGAAUGCCA
miR-124.1	1671	1677	m8	hsa-miR-124a	UUAAGGCACGCGGUGAAUGCCA
miR-124/506	1625	1632	1A,m8	hsa-miR-506	UAAGGCACCCUUCUGAGUAGA
				hsa-miR-124^brain	UAAGGCACGCGGUGAAUGCC
				hsa-miR-506	UAAGGCACCCUUCUGAGUAGA
				hsa-miR-124^brain	UAAGGCACGCGGUGAAUGCC
miR-136	2517	2523	1A	hsa-miR-136	ACUCCAUUUGUUUUGAUGAUGGA
miR-139	1489	1495	m8	hsa-miR-139^brain	UCUACAGUGCACGUGUCU
miR-141/200a	1382	1389	1A,m8	hsa-miR-141	UAACACUGUCUGGUAAAGAUGG
miR-141/200a	1382	1389	1A,m8	hsa-miR-200a	UAACACUGUCUGGUAACGAUGU
miR-142-5p	3783	3790	1A,m8	hsa-miR-142-5p	CAUAAAGUAGAAAGCACUAC
miR-142-5p	3783	3790	1A,m8	hsa-miR-142-5p	CAUAAAGUAGAAAGCACUAC
miR-143	995	1001	m8	hsa-miR-143^brain	UGAGAUGAAGCACUGUAGCUCA
miR-144	1488	1494	1A	hsa-miR-144	UACAGUAUAGAUGAUGUACUAG
miR-146	1858	1865	1A,m8	hsa-miR-146a	UGAGAACUGAAUUCCAUGGGUU
miR-146	1858	1865	1A,m8	hsa-miR-146b^brain	UGAGAACUGAAUUCCAUAGGCU
miR-185	998	1004	m8	hsa-miR-185^brain	UGGAGAGAAAGGCAGUUC
miR-19	1548	1555	1A,m8	hsa-miR-19a	UGUGCAAAUCUAUGCAAAACUGA
miR-19	1548	1555	1A,m8	hsa-miR-19b	UGUGCAAAUCCAUGCAAAACUGA
miR-200bc/429	4217	4223	m8	hsa-miR-200b	UAAUACUGCCUGGUAAUGAUGAC
				hsa-miR-200c	UAAUACUGCCGGGUAAUGAUGG
				hsa-miR-429	UAAUACUGUCUGGUAAAACCGU
miR-203.1	3497	3503	1A	hsa-miR-203	UGAAAUGUUUAGGACCACUAG
miR-214	3154	3160	1A	hsa-miR-214^brain	ACAGCAGGCACAGACAGGCAG
miR-221/222	3833	3840	1A,m8	hsa-miR-221^brain	AGCUACAUUGUCUGCUGGGUUUC
miR-221/222	3833	3840	1A,m8	hsa-miR-222^brain	AGCUACAUCUGGCUACUGGGUCUC
miR-26	1347	1353	1A	hsa-miR-26a^brain	UUCAAGUAAUCCAGGAUAGGC
miR-26	1347	1353	1A	hsa-miR-26b^SZ	UUCAAGUAAUUCAGGAUAGGUU
miR-299-5p	1422	1428	1A	hsa-miR-299-5p	UGGUUUACCGUCCCACAUACAU
miR-30-5p	1657	1663	1A	hsa-miR-30a-5p	UGUAAACAUCCUCGACUGGAAG
				hsa-miR-30c^brain	UGUAAACAUCCUACACUCUCAGC
				hsa-miR-30d^SZ	UGUAAACAUCCCCGACUGGAAG
				hsa-miR-30b^SZ	UGUAAACAUCCUACACUCAGCU
				hsa-miR-30e-5p	UGUAAACAUCCUUGACUGGA
miR-320	1803	1809	m8	hsa-miR-320	AAAAGCUGGGUUGAGAGGGCGAA
miR-323	3791	3797	m8	hsa-miR-323^brain	GCACAUUACACGGUCGACCUCU
miR-329	1365	1371	1A	hsa-miR-329^brain	AACACACCUGGUUAACCUCUUU
miR-329	1365	1371	1A	hsa-miR-329^brain	AACACACCUGGUUAACCUCUUU
miR-33	4257	4263	m8	hsa-miR-33	GUGCAUUGUAGUUGCAUUG
miR-33	4257	4263	m8	hsa-miR-33b	GUGCAUUGCUGUUGCAUUGCA
miR-330	3879	3886	1A,m8	hsa-miR-330^brain	GCAAAGCACACGGCCUGCAGAGA
miR-342	1918	1924	1A	hsa-miR-342^brain	UCUCACACAGAAAUCGCACCCGUC
miR-365	1510	1516	m8	hsa-miR-365	UAAUGCCCCUAAAAAUCCUUAU
miR-381	4207	4213	m8	hsa-miR-381	UAUACAAGGGCAAGCUCUCUGU
miR-410	3786	3792	1A	hsa-miR-410	AAUAUAACACAGAUGGCCUGU
miR-493-5p	3850	3856	m8	hsa-miR-493-5p	UUGUACAUGGUAGGCUUUCAUU
miR-493-5p	3850	3856	m8	hsa-miR-493-5p	UUGUACAUGGUAGGCUUUCAUU
miR-495	3653	3659	m8	hsa-miR-495^brain	AAACAAACAUGGUGCACUUCUUU
miR-495	3653	3659	m8	hsa-miR-495^brain	AAACAAACAUGGUGCACUUCUUU
miR-496	4078	4084	1A	hsa-miR-496	AUUACAUGGCCAAUCUC
miR-500	2508	2514	m8	hsa-miR-500	AUGCACCUGGGCAAGGAUUCUG
miR-505	170	176	m8	hsa-miR-505	GUCAACACUUGCUGGUUUCCUC
miR-543	1314	1320	1A	hsa-miR-543	AAACAUUCGCGGUGCACUUCU
miR-543	1314	1320	1A	hsa-miR-543	AAACAUUCGCGGUGCACUUCU
miR-9	2108	2115	1A,m8	hsa-miR-9^SZ	UCUUUGGUUAUCUAGCUGUAUGA

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.