Gene Page: F9

Summary
GeneID  2158
Symbol  F9
Synonyms  FIX|HEMB|MGC129641|MGC129642|PTC
Description  coagulation factor IX
See related  HGNC:3551|MIM:300746|Ensembl:ENSG00000101981|HPRD:02385|
Locus tag  RP6-88D7.1
Gene type  protein-coding
Map location  Xq27.1-q27.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
DOK50.820.71
SNX70.820.77
PTPN20.820.68
ZNF4350.810.71
ZNF6420.790.75
ZNF1930.790.67
HEATR10.770.62
ZNF3020.770.65
GPR850.760.60
SLC44A50.760.70
Top 10 negatively co-expressed genes
FBXO2-0.62-0.74
HLA-F-0.61-0.73
ZNF385A-0.59-0.71
ARHGAP22-0.59-0.75
LDHD-0.59-0.70
ATP10A-0.58-0.78
ALDOC-0.58-0.67
AIFM3-0.58-0.64
HLA-C-0.58-0.69
CA4-0.57-0.70
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004252serine-type endopeptidase activityTASglutamate (GO term level: 7)2472424 
GO:0005509calcium ion bindingIEA-
GO:0008233peptidase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006508proteolysisIEA-
GO:0007598blood coagulation, extrinsic pathwayEXP7598447 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionEXP8626656 
GO:0005576extracellular regionNAS14718574 
GO:0005634nucleusIDA18029348 
GO:0005737cytoplasmIDA18029348 
GO:0005886plasma membraneEXP2110473 |8626656 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
F2PTcoagulation factor II (thrombin)-HPRD15039440 
F7-coagulation factor VII (serum prothrombin conversion accelerator)-HPRD2248955 
F8AHF | DXS1253E | F8B | F8C | FVIII | HEMAcoagulation factor VIII, procoagulant component-HPRD11278963|11830468 
LRP1A2MR | APOER | APR | CD91 | FLJ16451 | IGFBP3R | LRP | MGC88725 | TGFBR5low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor)-HPRD,BioGRID12522212 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_COMPLEMENT_AND_COAGULATION_CASCADES 6949All SZGR genes in this pathway
BIOCARTA_INTRINSIC_PATHWAY 2315All SZGR genes in this pathway
BIOCARTA_PLATELETAPP_PATHWAY 1410All SZGR genes in this pathway
REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION 2717All SZGR genes in this pathway
REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS 118All SZGR genes in this pathway
REACTOME_METABOLISM_OF_PROTEINS 518242All SZGR genes in this pathway
REACTOME_FORMATION_OF_FIBRIN_CLOT_CLOTTING_CASCADE 3222All SZGR genes in this pathway
REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION 188116All SZGR genes in this pathway
REACTOME_INTRINSIC_PATHWAY 1712All SZGR genes in this pathway
REACTOME_HEMOSTASIS 466331All SZGR genes in this pathway
HSIAO_LIVER_SPECIFIC_GENES 244154All SZGR genes in this pathway
BROWN_MYELOID_CELL_DEVELOPMENT_DN 12986All SZGR genes in this pathway
SU_LIVER 5532All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_DN 540340All SZGR genes in this pathway
ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_DN 274165All SZGR genes in this pathway
TAVAZOIE_METASTASIS 10868All SZGR genes in this pathway
HOSHIDA_LIVER_CANCER_SURVIVAL_DN 11376All SZGR genes in this pathway
YAMASHITA_LIVER_CANCER_STEM_CELL_DN 7651All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_DN 267160All SZGR genes in this pathway
NABA_ECM_REGULATORS 238125All SZGR genes in this pathway
NABA_MATRISOME_ASSOCIATED 753411All SZGR genes in this pathway
NABA_MATRISOME 1028559All SZGR genes in this pathway


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