Gene Page: FCER1A

Summary
GeneID  2205
Symbol  FCER1A
Synonyms  FCE1A|FcERI
Description  Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
See related  HGNC:3609|MIM:147140|Ensembl:ENSG00000179639|HPRD:00917|
Locus tag  RP11-550P17.3
Gene type  protein-coding
Map location  1q23
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0235 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00814 
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004872receptor activityIEA-
GO:0019767IgE receptor activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0001820serotonin secretionIEAneuron, serotonin (GO term level: 7)-
GO:0001812positive regulation of type I hypersensitivityIEA-
GO:0007257activation of JNK activityIEA-
GO:0007166cell surface receptor linked signal transductionIEA-
GO:0019370leukotriene biosynthetic processIEA-
GO:0043306positive regulation of mast cell degranulationIEA-
GO:0050731positive regulation of peptidyl-tyrosine phosphorylationIEA-
GO:0050850positive regulation of calcium-mediated signalingIEA-
GO:0045401positive regulation of interleukin-3 biosynthetic processIEA-
GO:0045425positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic processIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0009897external side of plasma membraneIEA-
GO:0005886plasma membraneTAS1535625 
GO:0005887integral to plasma membraneIEA-
GO:0005887integral to plasma membraneTAS2964640 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
FCER1AFCE1A | FcERIFc fragment of IgE, high affinity I, receptor for; alpha polypeptide-HPRD11531339 
FCER1GFCRGFc fragment of IgE, high affinity I, receptor for; gamma polypeptide-HPRD,BioGRID8752908 
MS4A2APY | ATOPY | FCER1B | FCERI | IGEL | IGER | IGHER | MS4A1membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)-HPRD1535625 
VAV1VAVvav 1 guanine nucleotide exchange factorAffinity Capture-WesternBioGRID8900182 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_FC_EPSILON_RI_SIGNALING_PATHWAY 7958All SZGR genes in this pathway
KEGG_ASTHMA 3025All SZGR genes in this pathway
BIOCARTA_FCER1_PATHWAY 4130All SZGR genes in this pathway
PID_FCER1_PATHWAY 6243All SZGR genes in this pathway
JAEGER_METASTASIS_DN 258141All SZGR genes in this pathway
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_DN 14290All SZGR genes in this pathway
MULLIGHAN_MLL_SIGNATURE_1_DN 242165All SZGR genes in this pathway
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINED_IN_GRANULOCYTE_DN 76All SZGR genes in this pathway
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_DN 187115All SZGR genes in this pathway
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_GRANULOCYTE_DN 1713All SZGR genes in this pathway
KIM_MYCN_AMPLIFICATION_TARGETS_UP 9264All SZGR genes in this pathway
LIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_LARGE_VS_TINY_UP 4424All SZGR genes in this pathway
LIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_SMALL_VS_HUGE_UP 3829All SZGR genes in this pathway
BROWN_MYELOID_CELL_DEVELOPMENT_DN 12986All SZGR genes in this pathway
NAKAJIMA_MAST_CELL 4634All SZGR genes in this pathway
VERHAAK_AML_WITH_NPM1_MUTATED_DN 246180All SZGR genes in this pathway
KUMAR_TARGETS_OF_MLL_AF9_FUSION 405264All SZGR genes in this pathway
SMID_BREAST_CANCER_LUMINAL_B_DN 564326All SZGR genes in this pathway
SMID_BREAST_CANCER_NORMAL_LIKE_UP 476285All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_DN 701446All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_UP 338225All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_HGF_DN 235144All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_DN 245150All SZGR genes in this pathway
LIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_QTL 1710All SZGR genes in this pathway
WIERENGA_STAT5A_TARGETS_DN 213127All SZGR genes in this pathway
ZWANG_DOWN_BY_2ND_EGF_PULSE 293119All SZGR genes in this pathway
HECKER_IFNB1_TARGETS 9554All SZGR genes in this pathway


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