Gene Page: FCGR3B

Summary
GeneID  2215
Symbol  FCGR3B
Synonyms  CD16|CD16b|FCG3|FCGR3
Description  Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
See related  HGNC:3620|MIM:610665|Ensembl:ENSG00000162747|HPRD:09951|
Locus tag  -
Gene type  protein-coding
Map location  1q23
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00814 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
RCN20.780.78
PAIP20.740.73
GFM20.720.68
MRPL190.720.70
RAB4A0.720.70
DNAJB90.720.73
SRPRB0.720.66
DNAJA30.710.69
PTPLAD10.710.69
SLC25A30.710.66
Top 10 negatively co-expressed genes
AF347015.18-0.52-0.31
AF347015.21-0.47-0.24
AC010300.1-0.47-0.41
AC100783.1-0.45-0.40
AF347015.8-0.45-0.30
AC098691.2-0.45-0.31
AF347015.2-0.44-0.27
AF347015.26-0.43-0.27
MT-CO2-0.42-0.27
MT-ATP8-0.42-0.27
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004872receptor activityIEA-
GO:0019864IgG bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006955immune responseTAS2139735 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionIEA-
GO:0005886plasma membraneIEA-
GO:0031225anchored to membraneIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
APCSMGC88159 | PTX2 | SAPamyloid P component, serumReconstituted ComplexBioGRID11359830 
IGHG1-immunoglobulin heavy constant gamma 1 (G1m marker)-HPRD,BioGRID10917521 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_NATURAL_KILLER_CELL_MEDIATED_CYTOTOXICITY 13792All SZGR genes in this pathway
KEGG_LEISHMANIA_INFECTION 7256All SZGR genes in this pathway
KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS 140100All SZGR genes in this pathway
SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP 351230All SZGR genes in this pathway
SENGUPTA_NASOPHARYNGEAL_CARCINOMA_UP 294178All SZGR genes in this pathway
FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_DN 463290All SZGR genes in this pathway
JAATINEN_HEMATOPOIETIC_STEM_CELL_DN 226132All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_DN 1375806All SZGR genes in this pathway
FERRANDO_TAL1_NEIGHBORS 2115All SZGR genes in this pathway
TARTE_PLASMA_CELL_VS_PLASMABLAST_UP 398262All SZGR genes in this pathway
VERHAAK_AML_WITH_NPM1_MUTATED_UP 183111All SZGR genes in this pathway
MCLACHLAN_DENTAL_CARIES_DN 245144All SZGR genes in this pathway
MCLACHLAN_DENTAL_CARIES_UP 253147All SZGR genes in this pathway
MARTINELLI_IMMATURE_NEUTROPHIL_DN 139All SZGR genes in this pathway
POOLA_INVASIVE_BREAST_CANCER_UP 288168All SZGR genes in this pathway


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