Gene Page: ATF5

Summary
GeneID  22809
Symbol  ATF5
Synonyms  ATFX|FLJ34666|HMFN0395
Description  activating transcription factor 5
See related  HGNC:790|MIM:606398|Ensembl:ENSG00000169136|HPRD:05906|
Locus tag  -
Gene type  protein-coding
Map location  19q13.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenia, schizophrenias]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
BCL90.970.97
BCORL10.970.97
MLL50.960.96
ARID1A0.960.97
PHF120.960.96
PIK3C2B0.960.95
POGZ0.960.96
CREBBP0.960.96
EP3000.950.95
C11orf300.950.96
Top 10 negatively co-expressed genes
AF347015.31-0.72-0.90
C5orf53-0.72-0.78
S100B-0.72-0.86
AIFM3-0.72-0.77
MT-CO2-0.71-0.90
AF347015.27-0.71-0.87
FXYD1-0.71-0.88
HLA-F-0.70-0.75
SERPINB6-0.70-0.77
TSC22D4-0.70-0.79
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003700transcription factor activityIEA-
GO:0003702RNA polymerase II transcription factor activityTAS10373550 
GO:0003714transcription corepressor activityTAS10373550 
GO:0043565sequence-specific DNA bindingIEA-
GO:0046983protein dimerization activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006357regulation of transcription from RNA polymerase II promoterTAS10373550 
GO:0006350transcriptionIEA-
GO:0006916anti-apoptosisIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIEA-
GO:0005667transcription factor complexIEA-
GO:0005737cytoplasmIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CD34-CD34 moleculeTwo-hybridBioGRID10373550 
CDC34E2-CDC34 | UBC3 | UBE2R1cell division cycle 34 homolog (S. cerevisiae)-HPRD10373550 
CEBPGGPE1BP | IG/EBP-1CCAAT/enhancer binding protein (C/EBP), gamma-HPRD,BioGRID1371974 
DISC1C1orf136 | FLJ13381 | FLJ21640 | FLJ25311 | FLJ41105 | KIAA0457 | SCZD9disrupted in schizophrenia 1-HPRD,BioGRID12812986 
DISC-1 interacts with ATF5.BIND12812986 
GABBR1FLJ92613 | GABAB(1e) | GABABR1 | GABBR1-3 | GPRC3A | dJ271M21.1.1 | dJ271M21.1.2 | hGB1agamma-aminobutyric acid (GABA) B receptor, 1-HPRD,BioGRID11087824 
GABBR2FLJ36928 | GABABR2 | GPR51 | GPRC3B | HG20 | HRIHFB2099gamma-aminobutyric acid (GABA) B receptor, 2-HPRD,BioGRID11087824 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
PID_PRL_SIGNALING_EVENTS_PATHWAY 2317All SZGR genes in this pathway
HUTTMANN_B_CLL_POOR_SURVIVAL_UP 276187All SZGR genes in this pathway
WANG_LMO4_TARGETS_UP 372227All SZGR genes in this pathway
GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN 335193All SZGR genes in this pathway
OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_DN 275168All SZGR genes in this pathway
MULLIGHAN_NPM1_MUTATED_SIGNATURE_1_UP 276165All SZGR genes in this pathway
MULLIGHAN_NPM1_SIGNATURE_3_UP 341197All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_DN 1375806All SZGR genes in this pathway
PROVENZANI_METASTASIS_DN 13694All SZGR genes in this pathway
ENK_UV_RESPONSE_EPIDERMIS_DN 508354All SZGR genes in this pathway
GAUSSMANN_MLL_AF4_FUSION_TARGETS_F_DN 3324All SZGR genes in this pathway
BERENJENO_TRANSFORMED_BY_RHOA_DN 394258All SZGR genes in this pathway
RAMJAUN_APOPTOSIS_BY_TGFB1_VIA_MAPK1_DN 86All SZGR genes in this pathway
YORDY_RECIPROCAL_REGULATION_BY_ETS1_AND_SP100_UP 2511All SZGR genes in this pathway
JAZAG_TGFB1_SIGNALING_UP 10869All SZGR genes in this pathway
TSAI_RESPONSE_TO_IONIZING_RADIATION 149101All SZGR genes in this pathway
NUYTTEN_NIPP1_TARGETS_DN 848527All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_UP 1037673All SZGR genes in this pathway
SUH_COEXPRESSED_WITH_ID1_AND_ID2_UP 1914All SZGR genes in this pathway
PENG_LEUCINE_DEPRIVATION_UP 14293All SZGR genes in this pathway
PENG_GLUCOSE_DEPRIVATION_UP 4826All SZGR genes in this pathway
CHESLER_BRAIN_QTL_TRANS 65All SZGR genes in this pathway
UEDA_PERIFERAL_CLOCK 169111All SZGR genes in this pathway
OKUMURA_INFLAMMATORY_RESPONSE_LPS 183115All SZGR genes in this pathway
PEART_HDAC_PROLIFERATION_CLUSTER_DN 7657All SZGR genes in this pathway
PENG_RAPAMYCIN_RESPONSE_DN 245154All SZGR genes in this pathway
ZHAN_MULTIPLE_MYELOMA_CD1_UP 4529All SZGR genes in this pathway
ADDYA_ERYTHROID_DIFFERENTIATION_BY_HEMIN 7347All SZGR genes in this pathway
ZHANG_TARGETS_OF_EWSR1_FLI1_FUSION 8868All SZGR genes in this pathway
ZHAN_MULTIPLE_MYELOMA_CD1_VS_CD2_UP 6647All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
ZHU_CMV_ALL_UP 12089All SZGR genes in this pathway
WENG_POR_TARGETS_GLOBAL_DN 2314All SZGR genes in this pathway
ZHU_CMV_8_HR_UP 4739All SZGR genes in this pathway
TRACEY_RESISTANCE_TO_IFNA2_DN 3223All SZGR genes in this pathway
WENG_POR_TARGETS_LIVER_DN 2011All SZGR genes in this pathway
KRIGE_AMINO_ACID_DEPRIVATION 2920All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP 953554All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP 783442All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_1 528324All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_UNSTIMULATED 1229713All SZGR genes in this pathway
WANG_LSD1_TARGETS_DN 3930All SZGR genes in this pathway
HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_DN 281179All SZGR genes in this pathway
HANN_RESISTANCE_TO_BCL2_INHIBITOR_DN 4831All SZGR genes in this pathway
ACEVEDO_NORMAL_TISSUE_ADJACENT_TO_LIVER_TUMOR_DN 354216All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_DN 540340All SZGR genes in this pathway
ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_DN 274165All SZGR genes in this pathway
CHUNG_BLISTER_CYTOTOXICITY_UP 13484All SZGR genes in this pathway
BOQUEST_STEM_CELL_CULTURED_VS_FRESH_UP 425298All SZGR genes in this pathway
BLUM_RESPONSE_TO_SALIRASIB_UP 245159All SZGR genes in this pathway
BOHN_PRIMARY_IMMUNODEFICIENCY_SYNDROM_UP 4730All SZGR genes in this pathway
LINDSTEDT_DENDRITIC_CELL_MATURATION_A 6752All SZGR genes in this pathway
SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A12 317177All SZGR genes in this pathway
MILI_PSEUDOPODIA_CHEMOTAXIS_UP 7445All SZGR genes in this pathway
MARTENS_TRETINOIN_RESPONSE_DN 841431All SZGR genes in this pathway
GREGORY_SYNTHETIC_LETHAL_WITH_IMATINIB 14583All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_LATE 1137655All SZGR genes in this pathway
FEVR_CTNNB1_TARGETS_UP 682433All SZGR genes in this pathway
PHONG_TNF_RESPONSE_NOT_VIA_P38 337236All SZGR genes in this pathway
BOSCO_TH1_CYTOTOXIC_MODULE 11462All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-141/200a730736m8hsa-miR-141UAACACUGUCUGGUAAAGAUGG
hsa-miR-200aUAACACUGUCUGGUAACGAUGU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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