Gene Page

Gene Page: LPHN1

Summary

GeneID

22859

Symbol

LPHN1

Synonyms

CIRL1|CL1|LEC2

Description

latrophilin 1

Locus tag

Gene type

protein-coding

Map location

19p13.2

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GO_Annotation

Mapping neuro-related keywords to Gene Ontology annotations

Hits with neuro-related keywords: 1

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0004872

receptor activity

IEA

GO:0005529

sugar binding

IEA

GO:0004930

G-protein coupled receptor activity

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0007218

neuropeptide signaling pathway

IEA

Neurotransmitter (GO term level: 8)

GO:0007165

signal transduction

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0016021

integral to membrane

IEA

GO:0005886

plasma membrane

IEA

Interactions

Shown by Network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
SHANK1	SPANK-1 \| SSTRIP \| synamon	SH3 and multiple ankyrin repeat domains 1	CIRL1 interacts with SSTRIP. This interaction was modeled on a demonstrated interaction between CIRL1 from an unspecified species and human SSTRIP .	BIND	10964907
SHANK1	SPANK-1 \| SSTRIP \| synamon	SH3 and multiple ankyrin repeat domains 1	Two-hybrid	BioGRID	10964907
SHANK2	CORTBP1 \| CTTNBP1 \| ProSAP1 \| SHANK \| SPANK-3	SH3 and multiple ankyrin repeat domains 2	-	HPRD,BioGRID	10964907

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-10	190	196	m8	hsa-miR-10a	UACCCUGUAGAUCCGAAUUUGUG
miR-10	190	196	m8	hsa-miR-10b	UACCCUGUAGAACCGAAUUUGU
miR-124/506	2683	2689	m8	hsa-miR-506	UAAGGCACCCUUCUGAGUAGA
miR-124/506	2683	2689	m8	hsa-miR-124^brain	UAAGGCACGCGGUGAAUGCC
miR-129-5p	935	941	1A	hsa-miR-129^brain	CUUUUUGCGGUCUGGGCUUGC
miR-129-5p	935	941	1A	hsa-miR-129-5p	CUUUUUGCGGUCUGGGCUUGCU
miR-15/16/195/424/497	1906	1912	m8	hsa-miR-15a^brain	UAGCAGCACAUAAUGGUUUGUG
				hsa-miR-16^brain	UAGCAGCACGUAAAUAUUGGCG
				hsa-miR-15b^brain	UAGCAGCACAUCAUGGUUUACA
				hsa-miR-195^SZ	UAGCAGCACAGAAAUAUUGGC
				hsa-miR-424	CAGCAGCAAUUCAUGUUUUGAA
				hsa-miR-497	CAGCAGCACACUGUGGUUUGU
				hsa-miR-15a^brain	UAGCAGCACAUAAUGGUUUGUG
				hsa-miR-16^brain	UAGCAGCACGUAAAUAUUGGCG
				hsa-miR-15b^brain	UAGCAGCACAUCAUGGUUUACA
				hsa-miR-195^SZ	UAGCAGCACAGAAAUAUUGGC
				hsa-miR-424	CAGCAGCAAUUCAUGUUUUGAA
				hsa-miR-497	CAGCAGCACACUGUGGUUUGU
miR-182	2984	2990	1A	hsa-miR-182	UUUGGCAAUGGUAGAACUCACA
miR-183	1870	1876	m8	hsa-miR-183	UAUGGCACUGGUAGAAUUCACUG
miR-185	106	113	1A,m8	hsa-miR-185^brain	UGGAGAGAAAGGCAGUUC
miR-218	707	714	1A,m8	hsa-miR-218^brain	UUGUGCUUGAUCUAACCAUGU
miR-26	972	978	1A	hsa-miR-26a^brain	UUCAAGUAAUCCAGGAUAGGC
miR-26	972	978	1A	hsa-miR-26b^SZ	UUCAAGUAAUUCAGGAUAGGUU
miR-28	605	611	m8	hsa-miR-28^brain	AAGGAGCUCACAGUCUAUUGAG
miR-320	1110	1116	m8	hsa-miR-320	AAAAGCUGGGUUGAGAGGGCGAA
miR-326	1124	1130	1A	hsa-miR-326	CCUCUGGGCCCUUCCUCCAG
miR-339	189	195	m8	hsa-miR-339	UCCCUGUCCUCCAGGAGCUCA
miR-34/449	1245	1251	m8	hsa-miR-34a^brain	UGGCAGUGUCUUAGCUGGUUGUU
				hsa-miR-34c	AGGCAGUGUAGUUAGCUGAUUGC
				hsa-miR-449	UGGCAGUGUAUUGUUAGCUGGU
				hsa-miR-449b	AGGCAGUGUAUUGUUAGCUGGC
miR-34b	1246	1252	m8	hsa-miR-34b	UAGGCAGUGUCAUUAGCUGAUUG
miR-488	783	789	m8	hsa-miR-488	CCCAGAUAAUGGCACUCUCAA
miR-503	2001	2007	1A	hsa-miR-503	UAGCAGCGGGAACAGUUCUGCAG
miR-9	1318	1324	1A	hsa-miR-9^SZ	UCUUUGGUUAUCUAGCUGUAUGA
miR-9	1318	1324	1A	hsa-miR-9^SZ	UCUUUGGUUAUCUAGCUGUAUGA
miR-96	2984	2990	1A	hsa-miR-96^brain	UUUGGCACUAGCACAUUUUUGC

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.