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GeneID |
22953
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Symbol |
P2RX2
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Synonyms |
MGC129601|P2X2
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Description |
purinergic receptor P2X, ligand-gated ion channel, 2 |
See related |
HGNC:15459|MIM:600844|Ensembl:ENSG00000187848|HPRD:15984| |
Locus tag |
- |
Gene type |
protein-coding |
Map location |
12q24.33 |
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Gene set name |
Method of gene set |
Evidence |
Info |
Expression | Expression | P value: 1.413 | | GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 1 | |
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General Gene Expression (microarray) ? |
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Gene Expression in Brain Regions (new) |
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Top co-expressed genes in Brain Regions (new) |
|
Gene | Pearson's Correlation | Spearman's Correlation | | |
Top 10 positively co-expressed genes |
ZMYM2 | 0.95 | 0.96 | | |
PDS5A | 0.94 | 0.96 | | |
FBXO11 | 0.94 | 0.96 | | |
BCLAF1 | 0.94 | 0.97 | | |
C4orf41 | 0.94 | 0.96 | | |
THUMPD1 | 0.94 | 0.95 | | |
AP1G1 | 0.94 | 0.95 | | |
TP53BP1 | 0.94 | 0.95 | | |
PUM2 | 0.93 | 0.95 | | |
UBA6 | 0.93 | 0.95 | | |
Top 10 negatively co-expressed genes | FXYD1 | -0.79 | -0.86 | | |
AF347015.31 | -0.79 | -0.87 | | |
MT-CO2 | -0.78 | -0.87 | | |
AF347015.33 | -0.76 | -0.82 | | |
HIGD1B | -0.75 | -0.85 | | |
AF347015.27 | -0.75 | -0.83 | | |
AF347015.8 | -0.74 | -0.85 | | |
MT-CYB | -0.74 | -0.83 | | |
IFI27 | -0.74 | -0.83 | | |
HSD17B14 | -0.74 | -0.78 | | |
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Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0015276 | ligand-gated ion channel activity | TAS | Neurotransmitter (GO term level: 8) | 9119082 |
GO:0001614 | purinergic nucleotide receptor activity | NAS | | 17895406 |
GO:0004872 | receptor activity | IEA | | - |
GO:0004931 | ATP-gated cation channel activity | NAS | | 17895406 |
GO:0005524 | ATP binding | IEA | | - |
GO:0042803 | protein homodimerization activity | NAS | | 17895406 |
GO:0046982 | protein heterodimerization activity | NAS | | 17895406 |
Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0010524 | positive regulation of calcium ion transport into cytosol | NAS | | 17895406 |
GO:0006811 | ion transport | IEA | | - |
GO:0050850 | positive regulation of calcium-mediated signaling | NAS | | 17895406 |
Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0016020 | membrane | IEA | | - |
GO:0016021 | integral to membrane | IEA | | - |
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