Gene Page: P2RX2

Summary
GeneID  22953
Symbol  P2RX2
Synonyms  MGC129601|P2X2
Description  purinergic receptor P2X, ligand-gated ion channel, 2
See related  HGNC:15459|MIM:600844|Ensembl:ENSG00000187848|HPRD:15984|
Locus tag  -
Gene type  protein-coding
Map location  12q24.33
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
ExpressionExpressionP value: 1.413 
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ZMYM20.950.96
PDS5A0.940.96
FBXO110.940.96
BCLAF10.940.97
C4orf410.940.96
THUMPD10.940.95
AP1G10.940.95
TP53BP10.940.95
PUM20.930.95
UBA60.930.95
Top 10 negatively co-expressed genes
FXYD1-0.79-0.86
AF347015.31-0.79-0.87
MT-CO2-0.78-0.87
AF347015.33-0.76-0.82
HIGD1B-0.75-0.85
AF347015.27-0.75-0.83
AF347015.8-0.74-0.85
MT-CYB-0.74-0.83
IFI27-0.74-0.83
HSD17B14-0.74-0.78
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0015276ligand-gated ion channel activityTASNeurotransmitter (GO term level: 8)9119082 
GO:0001614purinergic nucleotide receptor activityNAS17895406 
GO:0004872receptor activityIEA-
GO:0004931ATP-gated cation channel activityNAS17895406 
GO:0005524ATP bindingIEA-
GO:0042803protein homodimerization activityNAS17895406 
GO:0046982protein heterodimerization activityNAS17895406 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0010524positive regulation of calcium ion transport into cytosolNAS17895406 
GO:0006811ion transportIEA-
GO:0050850positive regulation of calcium-mediated signalingNAS17895406 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0016020membraneIEA-
GO:0016021integral to membraneIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
GABRR1MGC163216gamma-aminobutyric acid (GABA) receptor, rho 1-HPRD14660627 
P2RX1P2X1purinergic receptor P2X, ligand-gated ion channel, 1-HPRD15313628 
P2RX2MGC129601 | P2X2purinergic receptor P2X, ligand-gated ion channel, 2-HPRD15313628 
P2RX3MGC129956 | P2X3purinergic receptor P2X, ligand-gated ion channel, 3-HPRD7566120 
 
Pathway annotation


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