Gene Page: UNC13A

Summary
GeneID  23025
Symbol  UNC13A
Synonyms  KIAA1032|Munc13-1
Description  unc-13 homolog A (C. elegans)
See related  HGNC:23150|MIM:609894|
Locus tag  -
Gene type  protein-coding
Map location  19p13.11
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
YWHAG0.930.93
WDR370.920.93
GABRB30.920.94
UBQLN10.920.93
EAF10.910.93
KIAA14680.910.92
MTPN0.900.91
G3BP20.900.93
BTRC0.900.91
STAM0.900.91
Top 10 negatively co-expressed genes
FXYD1-0.68-0.68
HIGD1B-0.66-0.67
MT-CO2-0.65-0.67
AF347015.21-0.64-0.66
AL139819.3-0.64-0.67
AP002478.3-0.64-0.68
TLCD1-0.63-0.64
AF347015.31-0.63-0.65
AC021016.1-0.63-0.62
CLDN10-0.62-0.63
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0008270zinc ion bindingIEA-
GO:0019992diacylglycerol bindingIEA-
GO:0046872metal ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0016188synaptic vesicle maturationIEASynap (GO term level: 8)-
GO:0007242intracellular signaling cascadeIEA-
GO:0006887exocytosisIEA-
GO:0050435beta-amyloid metabolic processIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0045202synapseIEAneuron, Synap, Neurotransmitter, Glial (GO term level: 2)-
GO:0005737cytoplasmIEA-
GO:0005886plasma membraneIEA-
GO:0030054cell junctionIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
BSNZNF231bassoon (presynaptic cytomatrix protein)Affinity Capture-WesternBioGRID14734538 
ERC2CAST | CAST1 | ELKSL | KIAA0378 | MGC133063 | MGC133064 | SPBC110 | Spc110ELKS/RAB6-interacting/CAST family member 2Affinity Capture-WesternBioGRID14734538 
 
Pathway annotation
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-129-5p396739741A,m8hsa-miR-129brainCUUUUUGCGGUCUGGGCUUGC
hsa-miR-129-5pCUUUUUGCGGUCUGGGCUUGCU
miR-130/301464146481A,m8hsa-miR-130abrainCAGUGCAAUGUUAAAAGGGCAU
hsa-miR-301CAGUGCAAUAGUAUUGUCAAAGC
hsa-miR-130bbrainCAGUGCAAUGAUGAAAGGGCAU
hsa-miR-454-3pUAGUGCAAUAUUGCUUAUAGGGUUU
miR-133418841941Ahsa-miR-133aUUGGUCCCCUUCAACCAGCUGU
hsa-miR-133bUUGGUCCCCUUCAACCAGCUA
miR-15/16/195/424/4978949011A,m8hsa-miR-15abrainUAGCAGCACAUAAUGGUUUGUG
hsa-miR-16brainUAGCAGCACGUAAAUAUUGGCG
hsa-miR-15bbrainUAGCAGCACAUCAUGGUUUACA
hsa-miR-195SZUAGCAGCACAGAAAUAUUGGC
hsa-miR-424CAGCAGCAAUUCAUGUUUUGAA
hsa-miR-497CAGCAGCACACUGUGGUUUGU
miR-1946404646m8hsa-miR-19aUGUGCAAAUCUAUGCAAAACUGA
hsa-miR-19bUGUGCAAAUCCAUGCAAAACUGA
miR-218601607m8hsa-miR-218brainUUGUGCUUGAUCUAACCAUGU
miR-22445774583m8hsa-miR-224CAAGUCACUAGUGGUUCCGUUUA
miR-450396739731Ahsa-miR-450UUUUUGCGAUGUGUUCCUAAUA
miR-5038959011Ahsa-miR-503UAGCAGCGGGAACAGUUCUGCAG
miR-941904196m8hsa-miR-9SZUCUUUGGUUAUCUAGCUGUAUGA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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