Gene Page

Home
Datasets
Search
Analysis & Tools
Documents
About SZGR
Quick search: (e.g. 207 or AKT)

Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

Gene Ranking Integration

Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

Release Site Map Support Contact us

Gene Page: MAP3K7IP2

Summary

GeneID

23118

Symbol

MAP3K7IP2

Synonyms

FLJ21885|KIAA0733|TAB2

Description

mitogen-activated protein kinase kinase kinase 7 interacting protein 2

Locus tag

Gene type

protein-coding

Map location

6q25.1-q25.3

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Literature

High-throughput literature-search

Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]

Click to show detail

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

CDK9

0.86

0.88

FLII

0.85

0.86

RHOT2

0.84

0.85

SH2B1

0.84

0.87

COG7

0.83

AC004410.1

0.83

0.85

LMF2

0.83

0.85

C19orf6

0.83

0.85

RCCD1

0.83

0.81

LZTR1

0.82

0.85

Top 10 negatively co-expressed genes

AF347015.21

-0.64

-0.69

AF347015.31

-0.63

-0.64

MT-CO2

-0.60

-0.62

AF347015.27

-0.59

-0.61

MT-CYB

-0.57

AF347015.8

-0.57

-0.58

AF347015.33

-0.56

C1orf54

-0.56

-0.63

GNG11

-0.56

-0.62

HIGD1B

-0.55

-0.57

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005515

protein binding

IPI

17158449

GO:0008270

zinc ion binding

IEA

GO:0046872

metal ion binding

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0043123

positive regulation of I-kappaB kinase/NF-kappaB cascade

IEP

12761501

GO:0043123

positive regulation of I-kappaB kinase/NF-kappaB cascade

ISS

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005829

cytosol

EXP

9162092 |9744859 |10066798
|12609980

GO:0005622

intracellular

IEA

GO:0005737

cytoplasm

IEA

GO:0016020

membrane

IEA

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
BAG2	BAG-2 \| KIAA0576 \| MGC149462 \| dJ417I1.2	BCL2-associated athanogene 2	-	HPRD	14743216
C1QBP	GC1QBP \| HABP1 \| SF2p32 \| gC1Q-R \| gC1qR \| p32	complement component 1, q subcomponent binding protein	-	HPRD	14743216
CAD	-	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase	-	HPRD	14743216
CALM3	PHKD \| PHKD3	calmodulin 3 (phosphorylase kinase, delta)	-	HPRD	14743216
CD82	4F9 \| C33 \| GR15 \| IA4 \| KAI1 \| R2 \| SAR2 \| ST6 \| TSPAN27	CD82 molecule	An unspecified isoform of MAP3K7IP2 (TAB2) interacts with the CD82 (KAI1) promoter.	BIND	15829968
CLTC	CHC \| CHC17 \| CLH-17 \| CLTCL2 \| Hc \| KIAA0034	clathrin, heavy chain (Hc)	-	HPRD	14743216
CS	-	citrate synthase	Affinity Capture-MS	BioGRID	14743216
DNAJA1	DJ-2 \| DjA1 \| HDJ2 \| HSDJ \| HSJ2 \| HSPF4 \| hDJ-2	DnaJ (Hsp40) homolog, subfamily A, member 1	-	HPRD	14743216
EEF1A2	EEF1AL \| EF-1-alpha-2 \| EF1A \| FLJ41696 \| HS1 \| STN \| STNL	eukaryotic translation elongation factor 1 alpha 2	-	HPRD	14743216
FLNA	ABP-280 \| ABPX \| DKFZp434P031 \| FLN \| FLN1 \| FMD \| MNS \| NHBP \| OPD \| OPD1 \| OPD2	filamin A, alpha (actin binding protein 280)	-	HPRD	14743216
HDAC1	DKFZp686H12203 \| GON-10 \| HD1 \| RPD3 \| RPD3L1	histone deacetylase 1	Reconstituted Complex	BioGRID	12150997
HDAC3	HD3 \| RPD3 \| RPD3-2	histone deacetylase 3	-	HPRD,BioGRID	12150997
HDAC5	FLJ90614 \| HD5 \| NY-CO-9	histone deacetylase 5	Reconstituted Complex	BioGRID	12150997
HNRNPH2	FTP3 \| HNRPH' \| HNRPH2 \| hnRNPH'	heterogeneous nuclear ribonucleoprotein H2 (H')	-	HPRD	14743216
HSP90AA1	FLJ31884 \| HSP86 \| HSP89A \| HSP90A \| HSP90N \| HSPC1 \| HSPCA \| HSPCAL1 \| HSPCAL4 \| HSPN \| Hsp89 \| Hsp90 \| LAP2	heat shock protein 90kDa alpha (cytosolic), class A member 1	-	HPRD	14743216
HSPA1A	FLJ54303 \| FLJ54370 \| FLJ54392 \| FLJ54408 \| FLJ75127 \| HSP70-1 \| HSP70-1A \| HSP70I \| HSP72 \| HSPA1 \| HSPA1B	heat shock 70kDa protein 1A	-	HPRD	14743216
HSPA2	HSP70-2 \| HSP70-3	heat shock 70kDa protein 2	-	HPRD	14743216
HSPA5	BIP \| FLJ26106 \| GRP78 \| MIF2	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	-	HPRD	14743216
HSPA8	HSC54 \| HSC70 \| HSC71 \| HSP71 \| HSP73 \| HSPA10 \| LAP1 \| MGC131511 \| MGC29929 \| NIP71	heat shock 70kDa protein 8	-	HPRD	14743216
HSPA9	CSA \| GRP75 \| HSPA9B \| MGC4500 \| MOT \| MOT2 \| MTHSP75 \| PBP74 \| mot-2	heat shock 70kDa protein 9 (mortalin)	-	HPRD	14743216
IRAK1	IRAK \| pelle	interleukin-1 receptor-associated kinase 1	-	HPRD	11518704
KIAA1967	DBC-1 \| DBC1	KIAA1967	-	HPRD	14743216
LGALS3BP	90K \| BTBD17B \| MAC-2-BP	lectin, galactoside-binding, soluble, 3 binding protein	-	HPRD	14743216
MAP3K7	TAK1 \| TGF1a	mitogen-activated protein kinase kinase kinase 7	-	HPRD,BioGRID	11259596
MAP3K7	TAK1 \| TGF1a	mitogen-activated protein kinase kinase kinase 7	-	HPRD	11259596 \|14743216
MAP3K7IP1	3'-Tab1 \| MGC57664 \| TAB1	mitogen-activated protein kinase kinase kinase 7 interacting protein 1	-	HPRD,BioGRID	14743216
MAP3K7IP2	FLJ21885 \| KIAA0733 \| TAB2	mitogen-activated protein kinase kinase kinase 7 interacting protein 2	-	HPRD	14743216
MAP3K7IP2	FLJ21885 \| KIAA0733 \| TAB2		Affinity Capture-Western	BioGRID	14633987
MAP3K7IP3	MGC45404 \| NAP1 \| TAB3	mitogen-activated protein kinase kinase kinase 7 interacting protein 3	Affinity Capture-Western	BioGRID	14633987
NCOR1	KIAA1047 \| MGC104216 \| N-CoR \| TRAC1 \| hCIT529I10 \| hN-CoR	nuclear receptor co-repressor 1	Affinity Capture-Western Reconstituted Complex Two-hybrid	BioGRID	12150997
NFKB1	DKFZp686C01211 \| EBP-1 \| KBF1 \| MGC54151 \| NF-kappa-B \| NFKB-p105 \| NFKB-p50 \| p105	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	Affinity Capture-Western Reconstituted Complex	BioGRID	12150997
RPL23	MGC111167 \| MGC117346 \| MGC72008 \| rpL17	ribosomal protein L23	-	HPRD	14743216
RPS27	MPS-1 \| MPS1	ribosomal protein S27	-	HPRD	14743216
RUVBL1	ECP54 \| INO80H \| NMP238 \| PONTIN \| Pontin52 \| RVB1 \| TIH1 \| TIP49 \| TIP49A	RuvB-like 1 (E. coli)	-	HPRD	14743216
RUVBL2	CGI-46 \| ECP51 \| INO80J \| REPTIN \| RVB2 \| TIH2 \| TIP48 \| TIP49B	RuvB-like 2 (E. coli)	-	HPRD	14743216
SEC13	D3S1231E \| SEC13L1 \| SEC13R \| npp-20	SEC13 homolog (S. cerevisiae)	-	HPRD	14743216
SPTAN1	(ALPHA)II-SPECTRIN \| FLJ44613 \| NEAS	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)	-	HPRD	14743216
TBL1X	EBI \| SMAP55 \| TBL1	transducin (beta)-like 1X-linked	Reconstituted Complex	BioGRID	12150997
TIMM50	MGC102733 \| TIM50 \| TIM50L	translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)	-	HPRD	14743216
TNFRSF11A	CD265 \| FEO \| LOH18CR1 \| ODFR \| OFE \| OPTB7 \| OSTS \| PDB2 \| RANK \| TRANCER	tumor necrosis factor receptor superfamily, member 11a, NFKB activator	-	HPRD,BioGRID	11809792
TRAF6	MGC:3310 \| RNF85	TNF receptor-associated factor 6	-	HPRD,BioGRID	10882101
TUBA3C	TUBA2 \| bA408E5.3	tubulin, alpha 3c	-	HPRD	14743216
TUBB4	TUBB5 \| beta-5	tubulin, beta 4	-	HPRD	14743216
UBA52	CEP52 \| HUBCEP52 \| MGC126879 \| MGC126881 \| MGC57125 \| RPL40	ubiquitin A-52 residue ribosomal protein fusion product 1	-	HPRD	14743216
XIAP	API3 \| BIRC4 \| ILP1 \| MIHA \| XLP2	X-linked inhibitor of apoptosis	-	HPRD,BioGRID	12048196
YWHAE	14-3-3E \| FLJ45465 \| KCIP-1 \| MDCR \| MDS	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	-	HPRD	14743216

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
let-7/98	160	166	1A	hsa-let-7a^brain	UGAGGUAGUAGGUUGUAUAGUU
				hsa-let-7b^brain	UGAGGUAGUAGGUUGUGUGGUU
				hsa-let-7c^brain	UGAGGUAGUAGGUUGUAUGGUU
				hsa-let-7d^brain	AGAGGUAGUAGGUUGCAUAGU
				hsa-let-7e^brain	UGAGGUAGGAGGUUGUAUAGU
				hsa-let-7f^brain	UGAGGUAGUAGAUUGUAUAGUU
				hsa-miR-98^brain	UGAGGUAGUAAGUUGUAUUGUU
				hsa-let-7g^SZ	UGAGGUAGUAGUUUGUACAGU
				hsa-let-7i^brain	UGAGGUAGUAGUUUGUGCUGU
miR-101	633	639	1A	hsa-miR-101	UACAGUACUGUGAUAACUGAAG
miR-103/107	913	920	1A,m8	hsa-miR-103^brain	AGCAGCAUUGUACAGGGCUAUGA
miR-103/107	913	920	1A,m8	hsa-miR-107^brain	AGCAGCAUUGUACAGGGCUAUCA
miR-142-3p	398	405	1A,m8	hsa-miR-142-3p	UGUAGUGUUUCCUACUUUAUGGA
miR-144	633	639	1A	hsa-miR-144	UACAGUAUAGAUGAUGUACUAG
miR-155	818	825	1A,m8	hsa-miR-155	UUAAUGCUAAUCGUGAUAGGGG
miR-181	1391	1397	1A	hsa-miR-181a^brain	AACAUUCAACGCUGUCGGUGAGU
				hsa-miR-181b^SZ	AACAUUCAUUGCUGUCGGUGGG
				hsa-miR-181c^brain	AACAUUCAACCUGUCGGUGAGU
				hsa-miR-181d^brain	AACAUUCAUUGUUGUCGGUGGGUU
miR-23	1742	1748	1A	hsa-miR-23a^brain	AUCACAUUGCCAGGGAUUUCC
miR-23	1742	1748	1A	hsa-miR-23b^brain	AUCACAUUGCCAGGGAUUACC
miR-26	1313	1319	1A	hsa-miR-26a^brain	UUCAAGUAAUCCAGGAUAGGC
miR-26	1313	1319	1A	hsa-miR-26b^SZ	UUCAAGUAAUUCAGGAUAGGUU
miR-27	541	547	1A	hsa-miR-27a^brain	UUCACAGUGGCUAAGUUCCGC
miR-27	541	547	1A	hsa-miR-27b^brain	UUCACAGUGGCUAAGUUCUGC
miR-376c	1739	1745	m8	hsa-miR-376c	AACAUAGAGGAAAUUCCACG

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.