Gene Page

Gene Page: XPO6

Summary

GeneID

23214

Symbol

XPO6

Synonyms

EXP6|FLJ22519|KIAA0370|RANBP20

Description

exportin 6

Locus tag

Gene type

protein-coding

Map location

16p11.2

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GSMA_IIE

genome scan meta-analysis (European-ancestry samples)

Psr: 0.01775

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005515

protein binding

IPI

14592989

GO:0008565

protein transporter activity

IDA

14592989

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0000059

protein import into nucleus, docking

IEA

GO:0006611

protein export from nucleus

IDA

14592989

GO:0006886

intracellular protein transport

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005634

nucleus

14592989

GO:0005643

nuclear pore

IEA

GO:0005737

cytoplasm

14592989

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
ACTA1	ACTA \| ASMA \| CFTD \| CFTD1 \| CFTDM \| MPFD \| NEM1 \| NEM2 \| NEM3	actin, alpha 1, skeletal muscle	Affinity Capture-MS	BioGRID	14592989
ACTB	PS1TP5BP1	actin, beta	-	HPRD	14592989
BRF2	BRFU \| FLJ11052 \| TFIIIB50	BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like	Affinity Capture-MS	BioGRID	17353931
DIAPH1	DFNA1 \| DIA1 \| DRF1 \| FLJ25265 \| LFHL1 \| hDIA1	diaphanous homolog 1 (Drosophila)	-	HPRD,BioGRID	14592989
EGFR	ERBB \| ERBB1 \| HER1 \| PIG61 \| mENA	epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)	-	HPRD	14592989
ENAH	ENA \| MENA \| NDPP1	enabled homolog (Drosophila)	Affinity Capture-MS	BioGRID	14592989
GSK3B	-	glycogen synthase kinase 3 beta	Affinity Capture-MS	BioGRID	17353931
NUP62	DKFZp547L134 \| FLJ20822 \| FLJ43869 \| IBSN \| MGC841 \| SNDI \| p62	nucleoporin 62kDa	Two-hybrid	BioGRID	16189514
PFN1	-	profilin 1	-	HPRD,BioGRID	14592989
RAN	ARA24 \| Gsp1 \| TC4	RAN, member RAS oncogene family	Affinity Capture-MS	BioGRID	14592989
VASP	-	vasodilator-stimulated phosphoprotein	-	HPRD,BioGRID	14592989

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-1/206	489	495	1A	hsa-miR-1	UGGAAUGUAAAGAAGUAUGUA
				hsa-miR-206^SZ	UGGAAUGUAAGGAAGUGUGUGG
				hsa-miR-613	AGGAAUGUUCCUUCUUUGCC
				hsa-miR-1	UGGAAUGUAAAGAAGUAUGUA
				hsa-miR-206^SZ	UGGAAUGUAAGGAAGUGUGUGG
				hsa-miR-613	AGGAAUGUUCCUUCUUUGCC
miR-539	481	487	1A	hsa-miR-539	GGAGAAAUUAUCCUUGGUGUGU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.