Gene Page: SNF1LK2

Summary
GeneID  23235
Symbol  SNF1LK2
Synonyms  DKFZp434K1115|KIAA0781|LOH11CR1I|QIK|SIK2
Description  SNF1-like kinase 2
See related  HGNC:21680|MIM:608973|Ensembl:ENSG00000170145|HPRD:12348|
Locus tag  -
Gene type  protein-coding
Map location  11q23.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.006 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
TCTEX1D20.800.87
NDUFS40.800.83
NDUFAF20.800.82
TXN0.780.75
GTF2A20.780.82
ATP5E0.780.74
CHCHD10.780.81
TXNDC170.770.79
ARL160.770.77
SNRPD20.770.77
Top 10 negatively co-expressed genes
AF347015.15-0.56-0.66
AF347015.26-0.55-0.67
EPAS1-0.55-0.68
MMRN2-0.54-0.57
AF347015.2-0.54-0.64
AF347015.8-0.53-0.62
MT-CYB-0.53-0.62
TGM2-0.53-0.62
PRELP-0.53-0.65
HLA-E-0.53-0.65
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0000287magnesium ion bindingIDA14976552 
GO:0005515protein bindingIEA-
GO:0005524ATP bindingIDA14976552 
GO:0004674protein serine/threonine kinase activityIDA14976552 
GO:0016740transferase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006468protein amino acid phosphorylationIDA14976552 
GO:0007243protein kinase cascadeIDA14976552 
GO:0046626regulation of insulin receptor signaling pathwayISS-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIEA-
GO:0005737cytoplasmISS-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CRTC2RP11-422P24.6 | TORC2CREB regulated transcription coactivator 2TORC2 interacts with SIK2.BIND15454081 
-HPRD,BioGRID15454081 
 
Pathway annotation
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-101268626921Ahsa-miR-101UACAGUACUGUGAUAACUGAAG
miR-103/107153215391A,m8hsa-miR-103brainAGCAGCAUUGUACAGGGCUAUGA
hsa-miR-107brainAGCAGCAUUGUACAGGGCUAUCA
miR-124/50610381044m8hsa-miR-506UAAGGCACCCUUCUGAGUAGA
hsa-miR-124brainUAAGGCACGCGGUGAAUGCC
miR-137121112171Ahsa-miR-137UAUUGCUUAAGAAUACGCGUAG
miR-142-3p26822688m8hsa-miR-142-3pUGUAGUGUUUCCUACUUUAUGGA
miR-144268626921Ahsa-miR-144UACAGUAUAGAUGAUGUACUAG
miR-1451261331A,m8hsa-miR-145GUCCAGUUUUCCCAGGAAUCCCUU
miR-218150815151A,m8hsa-miR-218brainUUGUGCUUGAUCUAACCAUGU
hsa-miR-218brainUUGUGCUUGAUCUAACCAUGU
miR-329267626821Ahsa-miR-329brainAACACACCUGGUUAACCUCUUU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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