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GeneID |
23293
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Symbol |
SMG6
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Synonyms |
C17orf31|EST1A|KIAA0732|SMG-6
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Description |
Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans) |
See related |
HGNC:17809|MIM:610963|Ensembl:ENSG00000070366|HPRD:06502| |
Locus tag |
- |
Gene type |
protein-coding |
Map location |
17p13.3 |
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Gene set name |
Method of gene set |
Evidence |
Info |
Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenic, schizophrenia] | Click to show detail |
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General Gene Expression (microarray) ? |
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Gene Expression in Brain Regions (new) |
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Top co-expressed genes in Brain Regions (new) |
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Gene | Pearson's Correlation | Spearman's Correlation | | |
Top 10 positively co-expressed genes |
NME3 | 0.75 | 0.74 | | |
HDHD3 | 0.74 | 0.74 | | |
GAMT | 0.72 | 0.75 | | |
PSMG4 | 0.72 | 0.72 | | |
BOLA1 | 0.71 | 0.70 | | |
ILVBL | 0.71 | 0.73 | | |
POMGNT1 | 0.70 | 0.68 | | |
NTHL1 | 0.69 | 0.71 | | |
C9orf142 | 0.69 | 0.67 | | |
RANGRF | 0.69 | 0.61 | | |
Top 10 negatively co-expressed genes | MT-ATP8 | -0.41 | -0.48 | | |
AF347015.2 | -0.40 | -0.42 | | |
AF347015.15 | -0.39 | -0.43 | | |
AF347015.8 | -0.39 | -0.43 | | |
AF347015.26 | -0.39 | -0.45 | | |
AF347015.18 | -0.38 | -0.45 | | |
COBLL1 | -0.38 | -0.37 | | |
ABCG2 | -0.37 | -0.41 | | |
MT-CYB | -0.36 | -0.42 | | |
CALD1 | -0.36 | -0.39 | | |
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Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0003677 | DNA binding | IEA | | - |
GO:0005515 | protein binding | IPI | | 12699629 |
GO:0004519 | endonuclease activity | IEA | | - |
GO:0016787 | hydrolase activity | IEA | | - |
GO:0042162 | telomeric DNA binding | IDA | | 12699629 |
GO:0030145 | manganese ion binding | IEA | | - |
GO:0046872 | metal ion binding | IEA | | - |
Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | TAS | | 16488880 |
GO:0000723 | telomere maintenance | IMP | | 12699629 |
GO:0006406 | mRNA export from nucleus | TAS | | 16488880 |
GO:0035303 | regulation of dephosphorylation | TAS | | 15721257 |
Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0000781 | chromosome, telomeric region | IEA | | - |
GO:0005634 | nucleus | IDA | | 14636577 |
GO:0005694 | chromosome | IEA | | - |
GO:0005697 | telomerase holoenzyme complex | TAS | | 12699629 |
GO:0005737 | cytoplasm | IDA | | 14636577 |
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- SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
- Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.
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