Gene Page: FPGS

Summary
GeneID  2356
Symbol  FPGS
Synonyms  -
Description  folylpolyglutamate synthase
See related  HGNC:3824|MIM:136510|Ensembl:ENSG00000136877|HPRD:00642|
Locus tag  RP11-228B15.1
Gene type  protein-coding
Map location  9q34.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 3 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004326tetrahydrofolylpolyglutamate synthase activityIEAglutamate (GO term level: 6)-
GO:0004326tetrahydrofolylpolyglutamate synthase activityISSglutamate (GO term level: 6)10964921 
GO:0004326tetrahydrofolylpolyglutamate synthase activityTASglutamate (GO term level: 6)7721888 
GO:0000166nucleotide bindingIEA-
GO:0005524ATP bindingIEA-
GO:0016874ligase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0009116nucleoside metabolic processISS10964921 
GO:0006139nucleobase, nucleoside, nucleotide and nucleic acid metabolic processTAS7721888 
GO:0009396folic acid and derivative biosynthetic processIEA-
GO:0009058biosynthetic processIEA-
GO:0006730one-carbon compound metabolic processIEA-
GO:0006544glycine metabolic processISS10964921 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005829cytosolTAS7721888 
GO:0005737cytoplasmTAS1409616 
GO:0005739mitochondrionTAS7721888 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_FOLATE_BIOSYNTHESIS 1110All SZGR genes in this pathway
REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS 5136All SZGR genes in this pathway
SCHLOSSER_MYC_AND_SERUM_RESPONSE_SYNERGY 3222All SZGR genes in this pathway
BENPORATH_MYC_TARGETS_WITH_EBOX 230156All SZGR genes in this pathway
FERNANDEZ_BOUND_BY_MYC 182116All SZGR genes in this pathway
ZHAN_V2_LATE_DIFFERENTIATION_GENES 4534All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_EARLY_PROGENITOR 532309All SZGR genes in this pathway
GRADE_COLON_CANCER_UP 871505All SZGR genes in this pathway
MOOTHA_HUMAN_MITODB_6_2002 429260All SZGR genes in this pathway
MOOTHA_MITOCHONDRIA 447277All SZGR genes in this pathway
DANG_BOUND_BY_MYC 1103714All SZGR genes in this pathway
LEE_BMP2_TARGETS_DN 882538All SZGR genes in this pathway
PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_UP 344215All SZGR genes in this pathway
KATSANOU_ELAVL1_TARGETS_DN 14888All SZGR genes in this pathway
SERVITJA_LIVER_HNF1A_TARGETS_DN 157105All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_2ND_EGF_PULSE_ONLY 1725838All SZGR genes in this pathway


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