Gene Page: PLXNB2

Summary
GeneID  23654
Symbol  PLXNB2
Synonyms  KIAA0315|MM1|Nbla00445|PLEXB2|dJ402G11.3
Description  plexin B2
See related  HGNC:9104|MIM:604293|Ensembl:ENSG00000196576|HPRD:05050|
Locus tag  RP3-402G11.19
Gene type  protein-coding
Map location  22q13.33
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0004872receptor activityIEA-
GO:0003674molecular_functionND-
GO:0005515protein bindingIEA-
GO:0005524ATP bindingIEA-
GO:0004812aminoacyl-tRNA ligase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0050772positive regulation of axonogenesisIEAaxon, neurogenesis (GO term level: 14)-
GO:0006418tRNA aminoacylation for protein translationIEA-
GO:0007165signal transductionIEA-
GO:0008150biological_processND-
GO:0007275multicellular organismal developmentIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005856cytoskeletonIDA18029348 
GO:0005575cellular_componentND-
GO:0005622intracellularIEA-
GO:0005737cytoplasmIDA18029348 
GO:0005737cytoplasmIEA-
GO:0016020membraneIEA-
GO:0016021integral to membraneIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ARHGEF11DKFZp667F1223 | GTRAP48 | KIAA0380 | PDZ-RHOGEFRho guanine nucleotide exchange factor (GEF) 11Affinity Capture-Western
Two-hybrid		BioGRID12123608 |12183458 
ARHGEF12DKFZp686O2372 | KIAA0382 | LARG | PRO2792Rho guanine nucleotide exchange factor (GEF) 12Affinity Capture-WesternBioGRID12183458 
PTNHARP | HBGF8 | HBNF | NEGF1pleiotrophinTwo-hybridBioGRID16169070 
RND1ARHS | FLJ42294 | RHO6 | RHOSRho family GTPase 1Two-hybridBioGRID12730235 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_AXON_GUIDANCE 129103All SZGR genes in this pathway
NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN 634384All SZGR genes in this pathway
MULLIGHAN_MLL_SIGNATURE_1_UP 380236All SZGR genes in this pathway
MULLIGHAN_MLL_SIGNATURE_2_UP 418263All SZGR genes in this pathway
DELYS_THYROID_CANCER_UP 443294All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP 1142669All SZGR genes in this pathway
GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP 612367All SZGR genes in this pathway
HUMMERICH_BENIGN_SKIN_TUMOR_DN 187All SZGR genes in this pathway
HUMMERICH_MALIGNANT_SKIN_TUMOR_DN 187All SZGR genes in this pathway
AMUNDSON_DNA_DAMAGE_RESPONSE_TP53 169All SZGR genes in this pathway
MEINHOLD_OVARIAN_CANCER_LOW_GRADE_UP 1915All SZGR genes in this pathway
MARTORIATI_MDM4_TARGETS_FETAL_LIVER_DN 514319All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_UP 1037673All SZGR genes in this pathway
NIKOLSKY_BREAST_CANCER_22Q13_AMPLICON 1715All SZGR genes in this pathway
ROSS_AML_WITH_CBFB_MYH11_FUSION 5232All SZGR genes in this pathway
PENG_LEUCINE_DEPRIVATION_UP 14293All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS 882572All SZGR genes in this pathway
ZHAN_MULTIPLE_MYELOMA_CD2_UP 4532All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_UP 390242All SZGR genes in this pathway
HENDRICKS_SMARCA4_TARGETS_UP 5635All SZGR genes in this pathway
KAAB_HEART_ATRIUM_VS_VENTRICLE_UP 249170All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
BURTON_ADIPOGENESIS_8 8657All SZGR genes in this pathway
BURTON_ADIPOGENESIS_7 5134All SZGR genes in this pathway
DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_DN 287208All SZGR genes in this pathway
BAELDE_DIABETIC_NEPHROPATHY_DN 434302All SZGR genes in this pathway
MARCHINI_TRABECTEDIN_RESISTANCE_DN 4934All SZGR genes in this pathway
SWEET_LUNG_CANCER_KRAS_UP 491316All SZGR genes in this pathway
HAN_SATB1_TARGETS_DN 442275All SZGR genes in this pathway
CHEN_METABOLIC_SYNDROM_NETWORK 1210725All SZGR genes in this pathway
MILI_PSEUDOPODIA_CHEMOTAXIS_DN 457302All SZGR genes in this pathway
MILI_PSEUDOPODIA_HAPTOTAXIS_DN 668419All SZGR genes in this pathway
FONTAINE_FOLLICULAR_THYROID_ADENOMA_UP 7543All SZGR genes in this pathway
FONTAINE_PAPILLARY_THYROID_CARCINOMA_UP 6638All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_CLASSES_DN 210141All SZGR genes in this pathway
KARLSSON_TGFB1_TARGETS_DN 207139All SZGR genes in this pathway
MARTENS_TRETINOIN_RESPONSE_UP 857456All SZGR genes in this pathway
LEE_BMP2_TARGETS_UP 745475All SZGR genes in this pathway
FEVR_CTNNB1_TARGETS_UP 682433All SZGR genes in this pathway
SMIRNOV_RESPONSE_TO_IR_6HR_UP 16697All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY 1839928All SZGR genes in this pathway
NABA_ECM_AFFILIATED 17189All SZGR genes in this pathway
NABA_MATRISOME_ASSOCIATED 753411All SZGR genes in this pathway
NABA_MATRISOME 1028559All SZGR genes in this pathway


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