Gene Page: LSM5

Summary
GeneID  23658
Symbol  LSM5
Synonyms  FLJ12710|YER146W
Description  LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
See related  HGNC:17162|MIM:607285|Ensembl:ENSG00000106355|HPRD:06285|
Locus tag  -
Gene type  protein-coding
Map location  7p14.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0139 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003723RNA bindingTAS10369684 
GO:0005515protein bindingIPI15231747 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006397mRNA processingTAS10369684 
GO:0008380RNA splicingIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusTAS10369684 
GO:0030529ribonucleoprotein complexIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
EXOSC5MGC111224 | MGC12901 | RRP41B | RRP46 | Rrp46p | hRrp46p | p12Bexosome component 5-HPRD,BioGRID15231747 
HNRNPDAUF1 | AUF1A | HNRPD | P37 | hnRNPD0heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)-HPRD,BioGRID15231747 
LSM1CASM | YJL124CLSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae)-HPRD11920408 
LSM2C6orf28 | G7b | YBL026W | snRNPLSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)-HPRD11920408 
LSM3SMX4 | USS2 | YLR438CLSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)-HPRD11920408 
LSM4YER112WLSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)-HPRD11920408 
LSM6YDR378CLSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)-HPRD11920408 
LSM7YNL147WLSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)-HPRD11920408 
LSM8YJR022WLSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae)-HPRD11920408 
SMN1BCD541 | SMA | SMA1 | SMA2 | SMA3 | SMA4 | SMA@ | SMN | SMNT | T-BCD541survival of motor neuron 1, telomeric-HPRD10851237 
SNRPEB-raf | SMEsmall nuclear ribonucleoprotein polypeptide E-HPRD,BioGRID15231747 
SNRPFSMFsmall nuclear ribonucleoprotein polypeptide F-HPRD,BioGRID15231747 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_RNA_DEGRADATION 5937All SZGR genes in this pathway
KEGG_SPLICEOSOME 12872All SZGR genes in this pathway
REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE 1510All SZGR genes in this pathway
REACTOME_METABOLISM_OF_MRNA 284128All SZGR genes in this pathway
REACTOME_DEADENYLATION_DEPENDENT_MRNA_DECAY 4829All SZGR genes in this pathway
REACTOME_METABOLISM_OF_RNA 330155All SZGR genes in this pathway
ONKEN_UVEAL_MELANOMA_DN 526357All SZGR genes in this pathway
GAZDA_DIAMOND_BLACKFAN_ANEMIA_PROGENITOR_DN 6642All SZGR genes in this pathway
SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_UP 408247All SZGR genes in this pathway
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP 1382904All SZGR genes in this pathway
DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_UP 368234All SZGR genes in this pathway
WANG_LMO4_TARGETS_UP 372227All SZGR genes in this pathway
HOEBEKE_LYMPHOID_STEM_CELL_DN 8659All SZGR genes in this pathway
RHEIN_ALL_GLUCOCORTICOID_THERAPY_DN 362238All SZGR genes in this pathway
DITTMER_PTHLH_TARGETS_UP 11268All SZGR genes in this pathway
TIEN_INTESTINE_PROBIOTICS_24HR_UP 557331All SZGR genes in this pathway
KIM_WT1_TARGETS_DN 459276All SZGR genes in this pathway
KIM_WT1_TARGETS_12HR_DN 209122All SZGR genes in this pathway
GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_UP 181101All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_DN 1375806All SZGR genes in this pathway
XU_HGF_TARGETS_INDUCED_BY_AKT1_6HR 198All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_DN 855609All SZGR genes in this pathway
JAZAG_TGFB1_SIGNALING_UP 10869All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
PUJANA_CHEK2_PCC_NETWORK 779480All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_DN 1024594All SZGR genes in this pathway
FERREIRA_EWINGS_SARCOMA_UNSTABLE_VS_STABLE_UP 16792All SZGR genes in this pathway
BENPORATH_NANOG_TARGETS 988594All SZGR genes in this pathway
MOREAUX_B_LYMPHOCYTE_MATURATION_BY_TACI_DN 7345All SZGR genes in this pathway
MOREAUX_MULTIPLE_MYELOMA_BY_TACI_DN 172107All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_UP 390242All SZGR genes in this pathway
DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP 314201All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
WANG_SMARCE1_TARGETS_DN 371218All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
ZHENG_BOUND_BY_FOXP3 491310All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_UNSTIMULATED 1229713All SZGR genes in this pathway
MARSON_BOUND_BY_E2F4_UNSTIMULATED 728415All SZGR genes in this pathway
ZHANG_BREAST_CANCER_PROGENITORS_UP 425253All SZGR genes in this pathway
WEST_ADRENOCORTICAL_TUMOR_UP 294199All SZGR genes in this pathway
BLUM_RESPONSE_TO_SALIRASIB_DN 342220All SZGR genes in this pathway
MUELLER_PLURINET 299189All SZGR genes in this pathway
WONG_EMBRYONIC_STEM_CELL_CORE 335193All SZGR genes in this pathway
MARTENS_TRETINOIN_RESPONSE_DN 841431All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN 19721213All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_3_DN 918550All SZGR genes in this pathway
FEVR_CTNNB1_TARGETS_DN 553343All SZGR genes in this pathway
GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_UP 570339All SZGR genes in this pathway
BOUDOUKHA_BOUND_BY_IGF2BP2 11159All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-204/2111121191A,m8hsa-miR-204brainUUCCCUUUGUCAUCCUAUGCCU
hsa-miR-211UUCCCUUUGUCAUCCUUCGCCU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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