Gene Page: DARC

Summary
GeneID  2532
Symbol  DARC
Synonyms  CCBP1|CD234|Dfy|FY|GPD|GpFy|WBCQ1
Description  Duffy blood group, chemokine receptor
See related  HGNC:4035|MIM:110700|Ensembl:ENSG00000213088|HPRD:00192|
Locus tag  CTA-134P22.3
Gene type  protein-coding
Map location  1q21-q22
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0235 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00814 
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenic, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
C19orf60.850.86
SYVN10.850.86
ZNF3350.850.83
ATG2A0.850.86
SMG50.850.84
FAM160B20.840.85
CLCN70.840.84
KRBA10.840.84
CABIN10.830.84
PIGQ0.830.82
Top 10 negatively co-expressed genes
AF347015.21-0.64-0.65
GNG11-0.59-0.61
AF347015.31-0.58-0.56
C1orf54-0.57-0.60
MT-CO2-0.57-0.56
SYCP3-0.56-0.58
AL050337.1-0.54-0.58
AF347015.27-0.53-0.52
AF347015.8-0.53-0.52
CLEC2B-0.52-0.60
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004872receptor activityIEA-
GO:0004950chemokine receptor activityNAS-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007186G-protein coupled receptor protein signaling pathwayIEA-
GO:0007165signal transductionIEA-
GO:0006954inflammatory responseIEA-
GO:0006952defense responseNAS10570183 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0016021integral to membraneIEA-
GO:0005886plasma membraneTAS7689250 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CCL2GDCF-2 | HC11 | HSMCR30 | MCAF | MCP-1 | MCP1 | MGC9434 | SCYA2 | SMC-CFchemokine (C-C motif) ligand 2-HPRD,BioGRID13679391 
CCL5D17S136E | MGC17164 | RANTES | SCYA5 | SISd | TCP228chemokine (C-C motif) ligand 5-HPRD12081195 
CXCL1FSP | GRO1 | GROa | MGSA | MGSA-a | NAP-3 | SCYB1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)-HPRD7592830 
Reconstituted ComplexBioGRID13679391 
IL8CXCL8 | GCP-1 | GCP1 | LECT | LUCT | LYNAP | MDNCF | MONAP | NAF | NAP-1 | NAP1interleukin 8-HPRD9921412 
 


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