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|
| GeneID |
2556
|
| Symbol |
GABRA3
|
| Synonyms |
MGC33793
|
| Description |
gamma-aminobutyric acid (GABA) A receptor, alpha 3 |
| See related |
HGNC:4077|MIM:305660|Ensembl:ENSG00000011677|HPRD:02375| |
| Locus tag |
- |
| Gene type |
protein-coding |
| Map location |
Xq28 |
|
| |
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|
| Gene set name |
Method of gene set |
Evidence |
Info |
| Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia] | Click to show detail | | GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 4 | |
|
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| General Gene Expression (microarray) ? |
|
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| |
| Gene Expression in Brain Regions (new) |
|
| |
| Top co-expressed genes in Brain Regions (new) |
|
| Gene | Pearson's Correlation | Spearman's Correlation | | |
| Top 10 positively co-expressed genes |
| SLC32A1 | 0.76 | 0.90 | | |
| HS6ST2 | 0.68 | 0.80 | | |
| RCN1 | 0.67 | 0.64 | | |
| DLX5 | 0.66 | 0.40 | | |
| TMEM123 | 0.63 | 0.42 | | |
| GAD1 | 0.63 | 0.85 | | |
| CDC25B | 0.63 | 0.60 | | |
| TBL1X | 0.63 | 0.45 | | |
| DLX1 | 0.63 | 0.39 | | |
| MOBKL2B | 0.63 | 0.44 | | |
Top 10 negatively co-expressed genes | | METRNL | -0.32 | -0.42 | | |
| DAB1 | -0.27 | 0.00 | | |
| SCUBE1 | -0.27 | -0.22 | | |
| NEUROD6 | -0.27 | -0.06 | | |
| RNF182 | -0.27 | -0.28 | | |
| AF347015.2 | -0.26 | -0.12 | | |
| KLHL1 | -0.26 | 0.07 | | |
| SLA | -0.26 | 0.06 | | |
| AF347015.18 | -0.26 | -0.12 | | |
| TMEM108 | -0.26 | -0.04 | | |
|
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0004890 | GABA-A receptor activity | IEA | GABA (GO term level: 7) | - |
| GO:0008503 | benzodiazepine receptor activity | TAS | GABA, Neurotransmitter (GO term level: 6) | 8391122 |
| GO:0005254 | chloride channel activity | IEA | | - |
| GO:0005216 | ion channel activity | IEA | | - |
| GO:0005230 | extracellular ligand-gated ion channel activity | IEA | | - |
| GO:0031404 | chloride ion binding | IEA | | - |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0007214 | gamma-aminobutyric acid signaling pathway | TAS | GABA, Neurotransmitter (GO term level: 8) | 8391122 |
| GO:0006821 | chloride transport | IEA | | - |
| GO:0006811 | ion transport | IEA | | - |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0045211 | postsynaptic membrane | IEA | Synap, Neurotransmitter (GO term level: 5) | - |
| GO:0045202 | synapse | IEA | neuron, Synap, Neurotransmitter, Glial (GO term level: 2) | - |
| GO:0005856 | cytoskeleton | IDA | | 18029348 |
| GO:0005737 | cytoplasm | IDA | | 18029348 |
| GO:0005886 | plasma membrane | IEA | | - |
| GO:0005887 | integral to plasma membrane | TAS | | 8391122 |
| GO:0030054 | cell junction | IEA | | - |
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