Gene Page: GABRB1

Summary
GeneID  2560
Symbol  GABRB1
Synonyms  -
Description  gamma-aminobutyric acid (GABA) A receptor, beta 1
See related  HGNC:4081|MIM:137190|Ensembl:ENSG00000163288|HPRD:15924|
Locus tag  -
Gene type  protein-coding
Map location  4p12
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenic, schizophrenics, schizophrenia]Click to show detail
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 3 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0030594neurotransmitter receptor activityIEANeurotransmitter (GO term level: 5)-
GO:0004890GABA-A receptor activityTASGABA (GO term level: 7)2465923 
GO:0005254chloride channel activityIEA-
GO:0005216ion channel activityIEA-
GO:0005230extracellular ligand-gated ion channel activityIEA-
GO:0031404chloride ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007165signal transductionTAS2465923 
GO:0006811ion transportIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0045211postsynaptic membraneIEASynap, Neurotransmitter (GO term level: 5)-
GO:0045202synapseIEAneuron, Synap, Neurotransmitter, Glial (GO term level: 2)-
GO:0005886plasma membraneIEA-
GO:0005887integral to plasma membraneTAS2465923 
GO:0030054cell junctionIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
AKAP5AKAP75 | AKAP79 | H21A kinase (PRKA) anchor protein 5-HPRD12595241 
C1QBPGC1QBP | HABP1 | SF2p32 | gC1Q-R | gC1qR | p32complement component 1, q subcomponent binding protein-HPRD11350968 
PIK3CAMGC142161 | MGC142163 | PI3K | p110-alphaphosphoinositide-3-kinase, catalytic, alpha polypeptide-HPRD11606067 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION 272195All SZGR genes in this pathway
REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES 186155All SZGR genes in this pathway
REACTOME_NEURONAL_SYSTEM 279221All SZGR genes in this pathway
REACTOME_NEUROTRANSMITTER_RECEPTOR_BINDING_AND_DOWNSTREAM_TRANSMISSION_IN_THE_POSTSYNAPTIC_CELL 137110All SZGR genes in this pathway
REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 413270All SZGR genes in this pathway
REACTOME_GABA_A_RECEPTOR_ACTIVATION 1212All SZGR genes in this pathway
REACTOME_GABA_RECEPTOR_ACTIVATION 5240All SZGR genes in this pathway
REACTOME_ION_CHANNEL_TRANSPORT 5542All SZGR genes in this pathway
REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT 2121All SZGR genes in this pathway
BOGNI_TREATMENT_RELATED_MYELOID_LEUKEMIA_UP 3019All SZGR genes in this pathway
MARKEY_RB1_CHRONIC_LOF_DN 11878All SZGR genes in this pathway
JAZAG_TGFB1_SIGNALING_VIA_SMAD4_UP 10866All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN 428306All SZGR genes in this pathway
SANSOM_APC_TARGETS_DN 366238All SZGR genes in this pathway
HILLION_HMGA1_TARGETS 9071All SZGR genes in this pathway
ZHENG_GLIOBLASTOMA_PLASTICITY_UP 250168All SZGR genes in this pathway
LIN_NPAS4_TARGETS_UP 163100All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3K4ME2_AND_H3K27ME3 349234All SZGR genes in this pathway
KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP 756494All SZGR genes in this pathway
CHICAS_RB1_TARGETS_SENESCENT 572352All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_LATE 1137655All SZGR genes in this pathway
RAO_BOUND_BY_SALL4_ISOFORM_A 182108All SZGR genes in this pathway
ZWANG_EGF_INTERVAL_DN 214124All SZGR genes in this pathway


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.