Gene Page: POLR1A

Summary
GeneID  25885
Symbol  POLR1A
Synonyms  DKFZp586M0122|FLJ21915|MGC87965|RPA1|RPO1-4
Description  polymerase (RNA) I polypeptide A, 194kDa
See related  HGNC:17264|Ensembl:ENSG00000068654|HPRD:10161|
Locus tag  -
Gene type  protein-coding
Map location  2p11.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0004 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
PIK3R30.830.64
VAT10.820.72
LIMK20.810.70
SDC10.800.66
REEP10.780.64
ATP11C0.780.70
AC110814.10.780.64
SCUBE30.780.72
RCAN30.770.62
GPRIN20.770.63
Top 10 negatively co-expressed genes
SLC16A11-0.57-0.64
TMEM54-0.57-0.65
C5orf53-0.55-0.64
ASPHD1-0.54-0.62
CCNI2-0.53-0.66
HLA-F-0.53-0.60
LHPP-0.53-0.56
CA4-0.52-0.65
TNFSF12-0.52-0.61
SPARCL1-0.52-0.61
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000287magnesium ion bindingIEA-
GO:0003677DNA bindingIEA-
GO:0003899DNA-directed RNA polymerase activityIEA-
GO:0005515protein bindingIPI16514417 
GO:0016779nucleotidyltransferase activityIEA-
GO:0016740transferase activityIEA-
GO:0008270zinc ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006350transcriptionIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIEA-
GO:0005654nucleoplasmEXP9582279 |12393749 |12646563 
GO:0005736DNA-directed RNA polymerase I complexNAS-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ANP32BAPRIL | PHAPI2 | SSP29acidic (leucine-rich) nuclear phosphoprotein 32 family, member B-HPRD,BioGRID9285060 
CD3EAPASE-1 | CAST | MGC118851 | PAF49CD3e molecule, epsilon associated proteinFar WesternBioGRID15226435 
NFKBIBIKBB | TRIP9nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta-HPRD14743216 
NOLC1KIAA0035 | NOPP130 | NOPP140 | NS5ATP13 | P130nucleolar and coiled-body phosphoprotein 1-HPRD,BioGRID10567578 
POLR1EFLJ13390 | FLJ13970 | PAF53 | PRAF1 | RP11-405L18.3polymerase (RNA) I polypeptide E, 53kDa-HPRD,BioGRID15226435 
RRN3DKFZp566E104 | MGC104238 | TIFIARRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)-HPRD,BioGRID11250903 
TIF-IA interacts with RPA43. This interaction was modeled on a demonstrated interaction between human TIF-IA and mouse RPA43.BIND12393749 
 


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