Gene Page: UPF2

Summary
GeneID  26019
Symbol  UPF2
Synonyms  DKFZp434D222|HUPF2|KIAA1408|MGC138834|MGC138835|RENT2|smg-3
Description  UPF2 regulator of nonsense transcripts homolog (yeast)
See related  HGNC:17854|MIM:605529|Ensembl:ENSG00000151461|HPRD:10405|
Locus tag  -
Gene type  protein-coding
Map location  10p14-p13
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
MELK0.970.83
TTK0.970.86
PBK0.970.75
BUB10.960.82
DLGAP50.960.79
NDC800.960.72
CEP550.960.80
KIF230.960.84
SGOL10.960.73
ESCO20.960.83
Top 10 negatively co-expressed genes
HLA-F-0.46-0.76
AF347015.27-0.44-0.80
C5orf53-0.44-0.66
PTH1R-0.44-0.69
AF347015.31-0.44-0.79
AF347015.33-0.44-0.81
MT-CO2-0.44-0.82
FBXO2-0.44-0.62
AIFM3-0.44-0.71
TINAGL1-0.43-0.72
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003723RNA bindingIEA-
GO:0042802identical protein bindingIPI15231747 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decayTAS16488880 
GO:0006406mRNA export from nucleusTAS16488880 
GO:0016070RNA metabolic processIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIDA14636577 
GO:0005737cytoplasmIDA14636577 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
DCP1AFLJ21691 | HSA275986 | Nbla00360 | SMAD4IP1 | SMIFDCP1 decapping enzyme homolog A (S. cerevisiae)-HPRD12417715 
DCP2FLJ33245 | NUDT20DCP2 decapping enzyme homolog (S. cerevisiae)Affinity Capture-WesternBioGRID14527413 
EIF1A121 | EIF-1 | EIF1A | ISO1 | SUI1eukaryotic translation initiation factor 1-HPRD11073994 
EIF4A1DDX2A | EIF-4A | EIF4Aeukaryotic translation initiation factor 4A, isoform 1-HPRD,BioGRID11073994 
EXOSC10PM-Scl | PM/Scl-100 | PMSCL | PMSCL2 | RRP6 | Rrp6p | p2 | p3 | p4exosome component 10Affinity Capture-WesternBioGRID14527413 
EXOSC2RRP4 | Rrp4p | hRrp4p | p7exosome component 2Affinity Capture-WesternBioGRID14527413 
EXOSC4FLJ20591 | RRP41 | RRP41A | Rrp41p | SKI6 | Ski6p | hRrp41p | p12Aexosome component 4-HPRD,BioGRID14527413 
LSM1CASM | YJL124CLSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae)Two-hybridBioGRID15231747 
MAP1AFLJ77111 | MAP1L | MTAP1Amicrotubule-associated protein 1A-HPRD,BioGRID15231747 
PARNDANpoly(A)-specific ribonuclease (deadenylation nuclease)Affinity Capture-WesternBioGRID14527413 
RPS15MGC111130 | RIGribosomal protein S15-HPRD,BioGRID15231747 
RPS25-ribosomal protein S25-HPRD,BioGRID15231747 
SMG161E3.4 | ATX | KIAA0421 | LIPPI-3-kinase-related kinase SMG-1Affinity Capture-WesternBioGRID11544179 
SRRM1160-KD | MGC39488 | POP101 | SRM160serine/arginine repetitive matrix 1-HPRD,BioGRID12093754 
UPF1FLJ43809 | FLJ46894 | HUPF1 | KIAA0221 | NORF1 | RENT1 | pNORF1UPF1 regulator of nonsense transcripts homolog (yeast)Upf1 interacts with Upf2.BIND15680326 
-HPRD,BioGRID11073994 
-HPRD11073994 |12723973 
UPF2DKFZp434D222 | HUPF2 | KIAA1408 | MGC138834 | MGC138835 | RENT2 | smg-3UPF2 regulator of nonsense transcripts homolog (yeast)Affinity Capture-WesternBioGRID14527413 
UPF3AHUPF3A | RENT3A | UPF3UPF3 regulator of nonsense transcripts homolog A (yeast)-HPRD,BioGRID11163187 
UPF3BHUPF3B | MRXS14 | RENT3B | UPF3XUPF3 regulator of nonsense transcripts homolog B (yeast)-HPRD,BioGRID15231747 
XRN1DKFZp434P0721 | DKFZp686B22225 | DKFZp686F19113 | FLJ41903 | SEP15'-3' exoribonuclease 1-HPRD,BioGRID14527413 
XRN2-5'-3' exoribonuclease 2-HPRD,BioGRID15231747 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
REACTOME_METABOLISM_OF_MRNA 284128All SZGR genes in this pathway
REACTOME_METABOLISM_OF_RNA 330155All SZGR genes in this pathway
REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX 17657All SZGR genes in this pathway
HAHTOLA_MYCOSIS_FUNGOIDES_SKIN_UP 177113All SZGR genes in this pathway
SCHLOSSER_SERUM_RESPONSE_DN 712443All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_DN 855609All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN 483336All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK 1442892All SZGR genes in this pathway
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP 811508All SZGR genes in this pathway
WEI_MYCN_TARGETS_WITH_E_BOX 795478All SZGR genes in this pathway
SHEN_SMARCA2_TARGETS_UP 424268All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_14HR_UP 156101All SZGR genes in this pathway
RAMASWAMY_METASTASIS_UP 6643All SZGR genes in this pathway
TOYOTA_TARGETS_OF_MIR34B_AND_MIR34C 463262All SZGR genes in this pathway
GRADE_COLON_CANCER_UP 871505All SZGR genes in this pathway
ZHANG_TLX_TARGETS_36HR_DN 185116All SZGR genes in this pathway


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