Gene Page: GARS

Summary
GeneID  2617
Symbol  GARS
Synonyms  CMT2D|DSMAV|GlyRS|HMN5|SMAD1
Description  glycyl-tRNA synthetase
See related  HGNC:4162|MIM:600287|Ensembl:ENSG00000106105|HPRD:02617|
Locus tag  -
Gene type  protein-coding
Map location  7p15
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
HLA-B0.830.83
RSAD20.830.78
GBP20.820.84
GBP30.810.82
OAS20.800.77
ACSL50.790.81
BST20.790.81
CFB0.780.80
APOL30.780.84
PARP120.780.74
Top 10 negatively co-expressed genes
ZNF821-0.66-0.76
C18orf22-0.64-0.73
DBN1-0.64-0.73
DUSP12-0.64-0.73
SHF-0.64-0.73
MPP3-0.64-0.73
DPF1-0.64-0.74
DNAJC9-0.63-0.69
IP6K2-0.63-0.72
LYSMD1-0.63-0.72
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0005515protein bindingIEA-
GO:0005524ATP bindingIEA-
GO:0004820glycine-tRNA ligase activityTAS7753621 
GO:0016874ligase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0045055regulated secretory pathwayIEANeurotransmitter (GO term level: 7)-
GO:0006426glycyl-tRNA aminoacylationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005625soluble fractionTAS7961834 
GO:0005737cytoplasmTAS7961834 
GO:0030141secretory granuleIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
EEF1DEF-1D | EF1D | FLJ20897 | FP1047eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)GRS interacts with an unspecified isoform of EF-1-delta.BIND11829477 
-HPRD,BioGRID11829477 
GPHNGEPH | GPH | GPHRYN | KIAA1385gephyrinin vitro
in vivo
BioGRID10037506 
IARSFLJ20736 | IARS1 | ILRS | PRO0785isoleucyl-tRNA synthetase-HPRD,BioGRID8816763 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-2051551611Ahsa-miR-205UCCUUCAUUCCACCGGAGUCUG
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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