Gene Page: GBX2

Summary
GeneID  2637
Symbol  GBX2
Synonyms  -
Description  gastrulation brain homeobox 2
See related  HGNC:4186|MIM:601135|Ensembl:ENSG00000168505|HPRD:03087|
Locus tag  -
Gene type  protein-coding
Map location  2q37
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 6 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
SLC2A50.550.50
MRPL410.550.53
PTPMT10.540.59
BRP44L0.540.56
MSRB20.530.57
DCXR0.530.55
MTHFS0.530.56
IL17D0.520.52
C17orf890.510.49
MID1IP10.510.42
Top 10 negatively co-expressed genes
ZNF611-0.37-0.32
AFF2-0.37-0.29
ZNF91-0.36-0.32
AC010522.1-0.36-0.38
ZNF445-0.36-0.29
MAP1B-0.35-0.28
RP11-468B6.3-0.35-0.25
WNK3-0.35-0.24
ZNF749-0.35-0.30
AC011477.2-0.35-0.27
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003700transcription factor activityTAS9346236 
GO:0043565sequence-specific DNA bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007411axon guidanceIEAaxon (GO term level: 13)-
GO:0030902hindbrain developmentIEABrain (GO term level: 8)-
GO:0021555midbrain-hindbrain boundary morphogenesisIEABrain (GO term level: 11)-
GO:0021549cerebellum developmentIEABrain (GO term level: 10)-
GO:0021930granule cell precursor proliferationIEAneuron, glutamate (GO term level: 11)-
GO:0048483autonomic nervous system developmentIEAneuron (GO term level: 6)-
GO:0001755neural crest cell migrationIEA-
GO:0001569patterning of blood vesselsIEA-
GO:0006355regulation of transcription, DNA-dependentIEA-
GO:0008283cell proliferationIEA-
GO:0042472inner ear morphogenesisIEA-
GO:0021568rhombomere 2 developmentIEA-
GO:0035239tube morphogenesisIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIEA-
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
TANG_SENESCENCE_TP53_TARGETS_UP 3320All SZGR genes in this pathway
NUYTTEN_NIPP1_TARGETS_DN 848527All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_DN 1024594All SZGR genes in this pathway
BENPORATH_SUZ12_TARGETS 1038678All SZGR genes in this pathway
BENPORATH_EED_TARGETS 1062725All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3 1118744All SZGR genes in this pathway
BENPORATH_PRC2_TARGETS 652441All SZGR genes in this pathway
TESAR_ALK_TARGETS_HUMAN_ES_5D_UP 55All SZGR genes in this pathway
XU_GH1_EXOGENOUS_TARGETS_DN 12069All SZGR genes in this pathway
TESAR_ALK_TARGETS_EPISC_3D_UP 77All SZGR genes in this pathway
MEISSNER_BRAIN_HCP_WITH_H3K27ME3 269159All SZGR genes in this pathway
FIGUEROA_AML_METHYLATION_CLUSTER_4_DN 159All SZGR genes in this pathway
FIGUEROA_AML_METHYLATION_CLUSTER_6_DN 3819All SZGR genes in this pathway
CHYLA_CBFA2T3_TARGETS_UP 387225All SZGR genes in this pathway
HUANG_GATA2_TARGETS_DN 7252All SZGR genes in this pathway
DELACROIX_RAR_BOUND_ES 462273All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_2ND_EGF_PULSE_ONLY 1725838All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-369-3p2072131Ahsa-miR-369-3pAAUAAUACAUGGUUGAUCUUU
miR-374207213m8hsa-miR-374UUAUAAUACAACCUGAUAAGUG
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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