Gene Page: GCHFR

Summary
GeneID  2644
Symbol  GCHFR
Synonyms  GFRP|HsT16933|MGC138467|MGC138469|P35
Description  GTP cyclohydrolase I feedback regulator
See related  HGNC:4194|MIM:602437|Ensembl:ENSG00000137880|HPRD:03895|
Locus tag  -
Gene type  protein-coding
Map location  15q15
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 2 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
TSHR0.800.36
TNFRSF190.720.20
LTBP10.700.35
DMRT30.700.17
LRIG30.700.31
COL2A10.670.29
CYP39A10.660.37
SFRP20.660.35
PDLIM10.650.03
GPC40.640.27
Top 10 negatively co-expressed genes
MGLL-0.20-0.14
ASPHD1-0.17-0.06
PTH1R-0.16-0.07
KCNF1-0.16-0.07
CACNG3-0.16-0.10
HLA-F-0.16-0.03
CA11-0.16-0.03
NPM2-0.16-0.01
LGI4-0.150.03
GRASP-0.15-0.13
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI9092499 |16696853 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0042133neurotransmitter metabolic processTASneuron, axon, Synap, Neurotransmitter (GO term level: 8)8702680 
GO:0009890negative regulation of biosynthetic processIEA-
GO:0006809nitric oxide biosynthetic processTAS8702680 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0030425dendriteIDAneuron, axon, dendrite (GO term level: 6)16778797 
GO:0005634nucleusIDA16778797 
GO:0005737cytoplasmIDA16778797 
GO:0042470melanosomeIDA16778797 
GO:0031965nuclear membraneIDA16778797 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
GCH1DYT14 | DYT5 | GCH | GTP-CH-1 | GTPCH1GTP cyclohydrolase 1-HPRD8702680 
GCHFRGFRP | HsT16933 | MGC138467 | MGC138469 | P35GTP cyclohydrolase I feedback regulator-HPRD,BioGRID9092499 
 


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