Gene Page: GDF9

Summary
GeneID  2661
Symbol  GDF9
Synonyms  -
Description  growth differentiation factor 9
See related  HGNC:4224|MIM:601918|Ensembl:ENSG00000164404|HPRD:03560|
Locus tag  -
Gene type  protein-coding
Map location  5q31.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0032 
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.1991 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
TMED40.880.85
CIAO10.840.82
TPD52L20.840.82
TFG0.840.78
POLR2C0.820.76
PIGO0.820.77
PIGG0.820.79
C16orf580.810.76
MMS190.810.79
NCSTN0.810.77
Top 10 negatively co-expressed genes
AF347015.21-0.73-0.63
MT-CO2-0.68-0.60
AF347015.8-0.68-0.60
AF347015.18-0.67-0.65
AF347015.31-0.66-0.59
AF347015.27-0.65-0.60
MT-CYB-0.65-0.57
AF347015.2-0.64-0.56
MT-ATP8-0.63-0.61
AF347015.26-0.63-0.57
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005125cytokine activityIEA-
GO:0008083growth factor activityTAS8849725 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007292female gamete generationTAS7760846 |8849725 
GO:0007179transforming growth factor beta receptor signaling pathwayTAS7760846 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionIEA-
GO:0005615extracellular spaceIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ACVR2AACTRII | ACVR2activin A receptor, type IIA-HPRD12135884 
AOF2BHC110 | KDM1 | KIAA0601 | LSD1amine oxidase (flavin containing) domain 2Two-hybridBioGRID16169070 
BMPR1A10q23del | ACVRLK3 | ALK3 | CD292bone morphogenetic protein receptor, type IA-HPRD10712517 |12135884 
BMPR1BALK-6 | ALK6 | CDw293bone morphogenetic protein receptor, type IB-HPRD12135884 
BMPR2BMPR-II | BMPR3 | BMR2 | BRK-3 | FLJ41585 | FLJ76945 | PPH1 | T-ALKbone morphogenetic protein receptor, type II (serine/threonine kinase)-HPRD,BioGRID12135884 
BTBD2-BTB (POZ) domain containing 2Two-hybridBioGRID16169070 
CCDC53CGI-116coiled-coil domain containing 53Two-hybridBioGRID16169070 
CDKN2CINK4C | p18 | p18-INK4Ccyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)Two-hybridBioGRID16169070 
CRELD1AVSD2 | CIRRIN | DKFZp566D213cysteine-rich with EGF-like domains 1Two-hybridBioGRID16169070 
DLEU1BCMS | DLB1 | DLEU2 | LEU1 | LEU2 | MGC22430 | NCRNA00021 | XTP6deleted in lymphocytic leukemia 1 (non-protein coding)Two-hybridBioGRID16169070 
FOXG1BF1 | BF2 | FHKL3 | FKH2 | FKHL1 | FKHL2 | FKHL3 | FKHL4 | FOXG1A | FOXG1B | FOXG1C | HBF-1 | HBF-2 | HBF-3 | HBF-G2 | HBF2 | HFK1 | HFK2 | HFK3 | KHL2 | QINforkhead box G1Two-hybridBioGRID16169070 
FXYD6-FXYD domain containing ion transport regulator 6Two-hybridBioGRID16169070 
ILF3CBTF | DRBF | DRBP76 | MMP4 | MPHOSPH4 | MPP4 | NF-AT-90 | NF110 | NF90 | NFAR | NFAR-1 | NFAR2 | TCP110 | TCP80interleukin enhancer binding factor 3, 90kDaTwo-hybridBioGRID16169070 
KIF22KID | KNSL4 | OBP | OBP-1 | OBP-2kinesin family member 22Two-hybridBioGRID16169070 
LSM3SMX4 | USS2 | YLR438CLSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)Two-hybridBioGRID16169070 
MOBKL32C4D | CGI-95 | MGC12264 | MOB1 | MOB3 | PREI3MOB1, Mps One Binder kinase activator-like 3 (yeast)Two-hybridBioGRID16169070 
MPHOSPH6MPP | MPP-6 | MPP6M-phase phosphoprotein 6Two-hybridBioGRID16169070 
MYCBPAMY-1c-myc binding proteinTwo-hybridBioGRID16169070 
NDUFB9B22 | DKFZp566O173 | FLJ22885 | LYRM3 | UQOR22NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDaTwo-hybridBioGRID16169070 
ORAI2C7orf19 | CBCIP2 | FLJ12474 | FLJ14733 | FLJ44818 | TMEM142BORAI calcium release-activated calcium modulator 2Two-hybridBioGRID16169070 
PAFAH1B3-platelet-activating factor acetylhydrolase, isoform Ib, gamma subunit 29kDaTwo-hybridBioGRID16169070 
PCDHA4CNR1 | CNRN1 | CRNR1 | MGC138307 | MGC142169 | PCDH-ALPHA4protocadherin alpha 4Two-hybridBioGRID16169070 
PMF1-polyamine-modulated factor 1Two-hybridBioGRID16169070 
PRKRADYT16 | HSD14 | PACT | RAXprotein kinase, interferon-inducible double stranded RNA dependent activatorTwo-hybridBioGRID16169070 
PSMD11MGC3844 | Rpn6 | S9 | p44.5proteasome (prosome, macropain) 26S subunit, non-ATPase, 11Two-hybridBioGRID16169070 
RAB27AGS2 | HsT18676 | MGC117246 | RAB27 | RAMRAB27A, member RAS oncogene familyTwo-hybridBioGRID16169070 
RSRC1BM-011 | MGC12197arginine/serine-rich coiled-coil 1Two-hybridBioGRID16169070 
S100A860B8AG | CAGA | CFAG | CGLA | CP-10 | L1Ag | MA387 | MIF | MRP8 | NIF | P8S100 calcium binding protein A8Two-hybridBioGRID16169070 
SAT1DC21 | KFSD | SAT | SSAT | SSAT-1spermidine/spermine N1-acetyltransferase 1Two-hybridBioGRID16169070 
SERPINB9CAP-3 | CAP3 | PI9serpin peptidase inhibitor, clade B (ovalbumin), member 9Two-hybridBioGRID16169070 
SMN1BCD541 | SMA | SMA1 | SMA2 | SMA3 | SMA4 | SMA@ | SMN | SMNT | T-BCD541survival of motor neuron 1, telomericTwo-hybridBioGRID16169070 
SNRPGMGC117317 | SMGsmall nuclear ribonucleoprotein polypeptide GTwo-hybridBioGRID16169070 
STRN4FLJ35594 | ZIN | zinedinstriatin, calmodulin binding protein 4Two-hybridBioGRID16169070 
TDGF1CR | CRGF | CRIPTO | Cripto-1teratocarcinoma-derived growth factor 1Two-hybridBioGRID16169070 
TK1TK2thymidine kinase 1, solubleTwo-hybridBioGRID16169070 
TRIB3C20orf97 | NIPK | SINK | SKIP3 | TRB3tribbles homolog 3 (Drosophila)Two-hybridBioGRID16169070 
 


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