Gene Page: GFAP

Summary
GeneID  2670
Symbol  GFAP
Synonyms  FLJ45472
Description  glial fibrillary acidic protein
See related  HGNC:4235|MIM:137780|Ensembl:ENSG00000131095|HPRD:00675|
Locus tag  -
Gene type  protein-coding
Map location  17q21
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0584 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
APBB30.880.87
SGSM30.860.86
ABCB90.850.83
MAP3K120.850.83
NICN10.850.82
C16orf580.850.80
KAT2A0.850.83
TMEM250.840.84
SCYL10.840.82
PCYOX1L0.840.80
Top 10 negatively co-expressed genes
AF347015.2-0.66-0.49
AF347015.21-0.65-0.51
AL139819.3-0.65-0.63
AF347015.31-0.65-0.51
AF347015.8-0.64-0.50
MT-CO2-0.64-0.49
MT-CYB-0.63-0.49
AF347015.18-0.62-0.53
AF347015.26-0.62-0.47
AF347015.15-0.60-0.45
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005200structural constituent of cytoskeletonTAS2740350 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005882intermediate filamentTAS2740350 
GO:0005737cytoplasmIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CEP76C18orf9 | FLJ12542 | HsT1705centrosomal protein 76kDaTwo-hybridBioGRID16189514 
GRAP2GADS | GRAP-2 | GRB2L | GRBLG | GRID | GRPL | GrbX | Grf40 | Mona | P38GRB2-related adaptor protein 2Two-hybridBioGRID16189514 
KIAA0408FLJ43995 | RP3-403A15.2KIAA0408Two-hybridBioGRID16189514 
MEN1MEAI | SCG2multiple endocrine neoplasia I-HPRD,BioGRID12169273 
MYO15BFLJ21606 | FLJ22686 | FLJ40577 | FLJ44494 | MYO15BPmyosin XVB pseudogeneTwo-hybridBioGRID16189514 
PDLIM1CLIM1 | CLP-36 | CLP36 | hCLIM1PDZ and LIM domain 1Two-hybridBioGRID16189514 
PDLIM7LMP1PDZ and LIM domain 7 (enigma)Two-hybridBioGRID16189514 
PDZK1CAP70 | CLAMP | NHERF3 | PDZD1PDZ domain containing 1Two-hybridBioGRID16189514 
POM121DKFZp586G1822 | DKFZp586P2220 | FLJ41820 | KIAA0618 | MGC3792 | POM121APOM121 membrane glycoprotein (rat)Two-hybridBioGRID16189514 
PSEN1AD3 | FAD | PS1 | S182presenilin 1-HPRD,BioGRID12058025 
PSEN2AD3L | AD4 | PS2 | STM2presenilin 2 (Alzheimer disease 4)Two-hybridBioGRID12058025 
RIBC2C22orf11RIB43A domain with coiled-coils 2Two-hybridBioGRID16189514 
S100A1S100 | S100-alpha | S100AS100 calcium binding protein A1-HPRD10510252 
S100BNEF | S100 | S100betaS100 calcium binding protein B-HPRD10510252 
SH3YL1DKFZp586F1318 | FLJ39121 | RaySH3 domain containing, Ysc84-like 1 (S. cerevisiae)Two-hybridBioGRID16189514 
SRCASV | SRC1 | c-SRC | p60-Srcv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)-HPRD11379820 
TUBGCP476P | FLJ14797 | GCP4tubulin, gamma complex associated protein 4Two-hybridBioGRID16189514 
VIMFLJ36605vimentinTwo-hybridBioGRID16189514 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
REACTOME_SIGNALING_BY_ERBB4 9067All SZGR genes in this pathway
REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 3830All SZGR genes in this pathway
COLIN_PILOCYTIC_ASTROCYTOMA_VS_GLIOBLASTOMA_UP 3532All SZGR genes in this pathway
SHEPARD_CRUSH_AND_BURN_MUTANT_DN 185111All SZGR genes in this pathway
CHEN_LUNG_CANCER_SURVIVAL 2822All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_16HR_DN 8662All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_48HR_DN 504323All SZGR genes in this pathway
LU_AGING_BRAIN_UP 262186All SZGR genes in this pathway
LEE_AGING_NEOCORTEX_UP 8959All SZGR genes in this pathway
LEE_AGING_CEREBELLUM_UP 8458All SZGR genes in this pathway
NIELSEN_SCHWANNOMA_UP 1816All SZGR genes in this pathway
BANDRES_RESPONSE_TO_CARMUSTIN_MGMT_48HR_DN 161105All SZGR genes in this pathway
LEIN_ASTROCYTE_MARKERS 4235All SZGR genes in this pathway
LEIN_PONS_MARKERS 8959All SZGR genes in this pathway
HOQUE_METHYLATED_IN_CANCER 5645All SZGR genes in this pathway
LABBE_TARGETS_OF_TGFB1_AND_WNT3A_DN 10868All SZGR genes in this pathway
CUI_GLUCOSE_DEPRIVATION 6044All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
KYNG_WERNER_SYNDROM_AND_NORMAL_AGING_DN 225124All SZGR genes in this pathway
MIKKELSEN_MEF_HCP_WITH_H3_UNMETHYLATED 228119All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_4HR_DN 254158All SZGR genes in this pathway
KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP 756494All SZGR genes in this pathway
DEMAGALHAES_AGING_UP 5539All SZGR genes in this pathway


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