Gene Page: GHSR

Summary
GeneID  2693
Symbol  GHSR
Synonyms  -
Description  growth hormone secretagogue receptor
See related  HGNC:4267|MIM:601898|Ensembl:ENSG00000121853|HPRD:03541|
Locus tag  -
Gene type  protein-coding
Map location  3q26.31
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 2 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
CABP10.820.68
CCDC64B0.760.65
GLS20.750.68
ANXA110.740.73
ABTB10.740.68
TECR0.740.62
ISCU0.740.66
ACTR1B0.740.60
PRSS160.740.64
P2RX60.730.69
Top 10 negatively co-expressed genes
PKN1-0.44-0.51
PDE9A-0.42-0.53
NKIRAS2-0.42-0.36
SH2B2-0.41-0.54
TUBB2B-0.40-0.54
SH3BP2-0.40-0.52
KIAA1949-0.40-0.48
FADS2-0.39-0.41
MARCKSL1-0.39-0.44
YBX1-0.39-0.48
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0001616growth hormone secretagogue receptor activityIDA8688086 
GO:0004872receptor activityIEA-
GO:0016520growth hormone-releasing hormone receptor activityIDA8688086 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0051963regulation of synaptogenesisIEASynap (GO term level: 9)-
GO:0030252growth hormone secretionTAS16511605 
GO:0007186G-protein coupled receptor protein signaling pathwayIDA8688086 
GO:0007165signal transductionIEA-
GO:0008343adult feeding behaviorISS-
GO:0009755hormone-mediated signalingIDA8688086 
GO:0008154actin polymerization or depolymerizationIDA15232612 
GO:0032100positive regulation of appetiteISS-
GO:0040018positive regulation of multicellular organism growthIMP16511605 
GO:0032691negative regulation of interleukin-1 beta productionIDA15232612 
GO:0042536negative regulation of tumor necrosis factor biosynthetic processIDA15232612 
GO:0050728negative regulation of inflammatory responseIDA15232612 
GO:0043568positive regulation of insulin-like growth factor receptor signaling pathwayIEA-
GO:0046697decidualizationIDA17494105 
GO:0045409negative regulation of interleukin-6 biosynthetic processIDA15232612 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0043005neuron projectionIDAneuron, axon, neurite, dendrite (GO term level: 5)12890514 
GO:0016021integral to membraneIEA-
GO:0009986cell surfaceIDA8688086 
GO:0005886plasma membraneIEA-
GO:0045121membrane raftIDA15232612 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CORTCST-14 | CST-17 | CST-29cortistatin-HPRD11227737 
GHRLMTLRP | obestatinghrelin/obestatin prepropeptide-HPRD,BioGRID10604470 |11227737 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION 272195All SZGR genes in this pathway
REACTOME_GASTRIN_CREB_SIGNALLING_PATHWAY_VIA_PKC_AND_MAPK 205136All SZGR genes in this pathway
REACTOME_SIGNALING_BY_GPCR 920449All SZGR genes in this pathway
REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS 188108All SZGR genes in this pathway
REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS 305177All SZGR genes in this pathway
REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS 184116All SZGR genes in this pathway
REACTOME_GPCR_DOWNSTREAM_SIGNALING 805368All SZGR genes in this pathway
REACTOME_GPCR_LIGAND_BINDING 408246All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_FIMA_DN 284156All SZGR genes in this pathway
BENPORATH_SUZ12_TARGETS 1038678All SZGR genes in this pathway
BENPORATH_EED_TARGETS 1062725All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3 1118744All SZGR genes in this pathway
BENPORATH_PRC2_TARGETS 652441All SZGR genes in this pathway
BANDRES_RESPONSE_TO_CARMUSTIN_MGMT_48HR_DN 161105All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3 1069729All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3K4ME2_AND_H3K27ME3 349234All SZGR genes in this pathway
MIKKELSEN_NPC_HCP_WITH_H3K27ME3 341243All SZGR genes in this pathway
MIKKELSEN_MEF_HCP_WITH_H3K27ME3 590403All SZGR genes in this pathway
ZWANG_CLASS_1_TRANSIENTLY_INDUCED_BY_EGF 516308All SZGR genes in this pathway


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