Gene Page: EML4

Summary
GeneID  27436
Symbol  EML4
Synonyms  C2orf2|DKFZp686P18118|ELP120|FLJ10942|FLJ32318|ROPP120
Description  echinoderm microtubule associated protein like 4
See related  HGNC:1316|MIM:607442|Ensembl:ENSG00000143924|HPRD:06310|
Locus tag  -
Gene type  protein-coding
Map location  2p22-p21
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004252serine-type endopeptidase activityIEAglutamate (GO term level: 7)-
GO:0003993acid phosphatase activityIEA-
GO:0003674molecular_functionND-
GO:0005509calcium ion bindingIEA-
GO:0005515protein bindingIPI17353931 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006508proteolysisIEA-
GO:0007067mitosisNAS10995578 
GO:0007017microtubule-based processNAS10995578 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005874microtubuleIEA-
GO:0005737cytoplasmNAS10995578 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ARIH2ARI2 | FLJ10938 | FLJ33921 | TRIAD1ariadne homolog 2 (Drosophila)Two-hybridBioGRID16169070 
ARL4DARF4L | ARL6ADP-ribosylation factor-like 4DTwo-hybridBioGRID16169070 
NEK6SID6-1512NIMA (never in mitosis gene a)-related kinase 6Affinity Capture-MSBioGRID17353931 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_UP 579346All SZGR genes in this pathway
DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_DN 320184All SZGR genes in this pathway
VECCHI_GASTRIC_CANCER_EARLY_UP 430232All SZGR genes in this pathway
UDAYAKUMAR_MED1_TARGETS_UP 13582All SZGR genes in this pathway
VANHARANTA_UTERINE_FIBROID_WITH_7Q_DELETION_DN 3623All SZGR genes in this pathway
DARWICHE_SKIN_TUMOR_PROMOTER_UP 14296All SZGR genes in this pathway
DARWICHE_PAPILLOMA_RISK_LOW_DN 165107All SZGR genes in this pathway
DARWICHE_PAPILLOMA_RISK_HIGH_UP 147101All SZGR genes in this pathway
DARWICHE_SQUAMOUS_CELL_CARCINOMA_DN 181107All SZGR genes in this pathway
DARWICHE_PAPILLOMA_RISK_HIGH_VS_LOW_UP 66All SZGR genes in this pathway
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_DN 637377All SZGR genes in this pathway
RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_UP 236139All SZGR genes in this pathway
RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_MODERATELY_UP 10969All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN 514330All SZGR genes in this pathway
ONDER_CDH1_TARGETS_1_DN 169102All SZGR genes in this pathway
RADMACHER_AML_PROGNOSIS 7852All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_STEM_CELL_LONG_TERM 302191All SZGR genes in this pathway
MARTINEZ_RESPONSE_TO_TRABECTEDIN_DN 271175All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_3 720440All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_STIMULATED 1022619All SZGR genes in this pathway
KYNG_DNA_DAMAGE_BY_GAMMA_AND_UV_RADIATION 8865All SZGR genes in this pathway
KYNG_DNA_DAMAGE_UP 226164All SZGR genes in this pathway
ACEVEDO_NORMAL_TISSUE_ADJACENT_TO_LIVER_TUMOR_DN 354216All SZGR genes in this pathway
VANTVEER_BREAST_CANCER_ESR1_DN 240153All SZGR genes in this pathway
VANTVEER_BREAST_CANCER_BRCA1_UP 3618All SZGR genes in this pathway
BOYAULT_LIVER_CANCER_SUBCLASS_G3_UP 188121All SZGR genes in this pathway
CHANDRAN_METASTASIS_UP 221135All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_BOUND_8D 658397All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-1/206143914451Ahsa-miR-1UGGAAUGUAAAGAAGUAUGUA
hsa-miR-206SZUGGAAUGUAAGGAAGUGUGUGG
hsa-miR-613AGGAAUGUUCCUUCUUUGCC
miR-134105410611A,m8hsa-miR-134brainUGUGACUGGUUGACCAGAGGG
miR-142-3p572578m8hsa-miR-142-3pUGUAGUGUUUCCUACUUUAUGGA
hsa-miR-142-3pUGUAGUGUUUCCUACUUUAUGGA
miR-1452832891Ahsa-miR-145GUCCAGUUUUCCCAGGAAUCCCUU
miR-18314351441m8hsa-miR-183UAUGGCACUGGUAGAAUUCACUG
miR-208140614121Ahsa-miR-208AUAAGACGAGCAAAAAGCUUGU
miR-21620422048m8hsa-miR-216UAAUCUCAGCUGGCAACUGUG
miR-24225422601Ahsa-miR-24SZUGGCUCAGUUCAGCAGGAACAG
miR-29950956m8hsa-miR-29aSZUAGCACCAUCUGAAAUCGGUU
hsa-miR-29bSZUAGCACCAUUUGAAAUCAGUGUU
hsa-miR-29cSZUAGCACCAUUUGAAAUCGGU
miR-30-5p171517221A,m8hsa-miR-30a-5pUGUAAACAUCCUCGACUGGAAG
hsa-miR-30cbrainUGUAAACAUCCUACACUCUCAGC
hsa-miR-30dSZUGUAAACAUCCCCGACUGGAAG
hsa-miR-30bSZUGUAAACAUCCUACACUCAGCU
hsa-miR-30e-5pUGUAAACAUCCUUGACUGGA
miR-494223622421Ahsa-miR-494brainUGAAACAUACACGGGAAACCUCUU
miR-4957047111A,m8hsa-miR-495brainAAACAAACAUGGUGCACUUCUUU
miR-499140514121A,m8hsa-miR-499UUAAGACUUGCAGUGAUGUUUAA
miR-544228722931Ahsa-miR-544AUUCUGCAUUUUUAGCAAGU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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