Gene Page: GNAI3

Summary
GeneID  2773
Symbol  GNAI3
Synonyms  87U6|FLJ26559
Description  guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
See related  HGNC:4387|MIM:139370|Ensembl:ENSG00000065135|HPRD:00765|
Locus tag  -
Gene type  protein-coding
Map location  1p13
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.7926 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
PEF10.760.82
TSPAN310.760.77
SDHD0.750.73
C1orf430.740.72
TRUB20.730.77
SDHC0.730.79
C12orf620.720.70
C11orf590.720.83
MRPL170.710.74
ALG140.710.70
Top 10 negatively co-expressed genes
EIF5B-0.48-0.56
AC010300.1-0.40-0.52
AC005921.3-0.39-0.56
RBM25-0.36-0.36
AF347015.18-0.35-0.28
ANP32C-0.35-0.40
ZNF326-0.34-0.31
THOC2-0.34-0.29
UPF3B-0.33-0.31
SFRS12-0.33-0.31
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0004871signal transducer activityIEA-
GO:0003924GTPase activityTAS3109953 
GO:0005515protein bindingIEA-
GO:0005525GTP bindingIEA-
GO:0019001guanyl nucleotide bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007186G-protein coupled receptor protein signaling pathwayIEA-
GO:0007194negative regulation of adenylate cyclase activityTAS7608168 
GO:0007165signal transductionIEA-
GO:0006810transportNAS2452165 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005794Golgi apparatusIEA-
GO:0005737cytoplasmIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
C5AR1C5A | C5AR | C5R1 | CD88complement component 5a receptor 1Co-purificationBioGRID7962171 
CD48BCM1 | BLAST | BLAST1 | MEM-102 | SLAMF2 | hCD48 | mCD48CD48 molecule-HPRD8650218 
CD5916.3A5 | 1F5 | EJ16 | EJ30 | EL32 | FLJ38134 | FLJ92039 | G344 | HRF-20 | HRF20 | MAC-IP | MACIF | MEM43 | MGC2354 | MIC11 | MIN1 | MIN2 | MIN3 | MIRL | MSK21 | p18-20CD59 molecule, complement regulatory protein-HPRD8650218 
CNR1CANN6 | CB-R | CB1 | CB1A | CB1K5 | CB1R | CNRcannabinoid receptor 1 (brain)-HPRD,BioGRID11168387 
DRD2D2DR | D2Rdopamine receptor D2-HPRD10978845 
GNAI387U6 | FLJ26559guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3-HPRD12925752 
GPSM2LGN | PinsG-protein signaling modulator 2 (AGS3-like, C. elegans)-HPRD,BioGRID12925752 
LPAR1EDG2 | GPR26 | Gpcr26 | LPA1 | Mrec1.3 | VZG1 | edg-2 | rec.1.3 | vzg-1lysophosphatidic acid receptor 1-HPRD,BioGRID9600933 
MTNR1AMEL-1A-R | MT1melatonin receptor 1A-HPRD,BioGRID10598579 
RGS10-regulator of G-protein signaling 10Affinity Capture-Western
Biochemical Activity		BioGRID8774883 
-HPRD11443111 
RGS12DKFZp761K1617 | DKFZp761K1817regulator of G-protein signaling 12-HPRD,BioGRID11387333 
RGS14-regulator of G-protein signaling 14-HPRD,BioGRID11387333 
RGS16A28-RGS14 | A28-RGS14P | RGS-Rregulator of G-protein signaling 16-HPRD,BioGRID10072511 
RGS18RGS13regulator of G-protein signaling 18Reconstituted ComplexBioGRID11563974 |11955952 
-HPRD11563974|11955952 
RGS19GAIP | RGSGAIPregulator of G-protein signaling 19-HPRD,BioGRID8524874 |8986788 
RGS2G0S8regulator of G-protein signaling 2, 24kDaReconstituted ComplexBioGRID9079700 
RGS3C2PA | FLJ20370 | FLJ31516 | FLJ90496 | PDZ-RGS3 | RGP3regulator of G-protein signaling 3-HPRD,BioGRID9858594 
RGS5MST092 | MST106 | MST129 | MSTP032 | MSTP092 | MSTP106 | MSTP129regulator of G-protein signaling 5-HPRD,BioGRID9079700 
RGS7-regulator of G-protein signaling 7-HPRD,BioGRID10092682 
RIC8AMGC104517 | MGC131931 | MGC148073 | MGC148074 | RIC8 | synembrynresistance to inhibitors of cholinesterase 8 homolog A (C. elegans)-HPRD,BioGRID12509430 
S1PR1CHEDG1 | D1S3362 | ECGF1 | EDG-1 | EDG1 | FLJ58121 | S1P1sphingosine-1-phosphate receptor 1-HPRD,BioGRID8626678 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-124/50616791685m8hsa-miR-506UAAGGCACCCUUCUGAGUAGA
hsa-miR-124brainUAAGGCACGCGGUGAAUGCC
hsa-miR-506UAAGGCACCCUUCUGAGUAGA
hsa-miR-124brainUAAGGCACGCGGUGAAUGCC
miR-15/16/195/424/4978528591A,m8hsa-miR-15abrainUAGCAGCACAUAAUGGUUUGUG
hsa-miR-16brainUAGCAGCACGUAAAUAUUGGCG
hsa-miR-15bbrainUAGCAGCACAUCAUGGUUUACA
hsa-miR-195SZUAGCAGCACAGAAAUAUUGGC
hsa-miR-424CAGCAGCAAUUCAUGUUUUGAA
hsa-miR-497CAGCAGCACACUGUGGUUUGU
miR-153448454m8hsa-miR-153UUGCAUAGUCACAAAAGUGA
miR-182101610221Ahsa-miR-182UUUGGCAAUGGUAGAACUCACA
miR-200bc/429116411711A,m8hsa-miR-200bUAAUACUGCCUGGUAAUGAUGAC
hsa-miR-200cUAAUACUGCCGGGUAAUGAUGG
hsa-miR-429UAAUACUGUCUGGUAAAACCGU
miR-5038538591Ahsa-miR-503UAGCAGCGGGAACAGUUCUGCAG
miR-96101510221A,m8hsa-miR-96brainUUUGGCACUAGCACAUUUUUGC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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