Gene Page: GP1BA

Summary
GeneID  2811
Symbol  GP1BA
Synonyms  BSS|CD42B|CD42b-alpha|GP1B|MGC34595
Description  glycoprotein Ib (platelet), alpha polypeptide
See related  HGNC:4439|MIM:606672|Ensembl:ENSG00000185245|HPRD:01976|
Locus tag  -
Gene type  protein-coding
Map location  17pter-p12
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0424 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
RGS160.760.19
SUSD20.740.48
NPL0.720.29
SAMD110.720.45
RBPMS20.710.60
PAPPA0.700.16
CLMN0.700.37
FAM180B0.700.08
UBL4B0.700.33
NOD20.690.32
Top 10 negatively co-expressed genes
METTL10-0.43-0.49
UBE2Q2-0.42-0.47
ZNF184-0.41-0.44
CACNB3-0.40-0.24
VRK2-0.40-0.56
ARPC2-0.39-0.49
KLHDC2-0.39-0.51
ZNF639-0.39-0.55
LSM3-0.39-0.62
FRG1-0.39-0.61
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI7721887 |12855810 
GO:0015057thrombin receptor activityTAS12855810 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0000902cell morphogenesisIEA-
GO:0007155cell adhesionIDA9410473 
GO:0007166cell surface receptor linked signal transductionTAS3353370 
GO:0030168platelet activationTAS12855810 
GO:0030193regulation of blood coagulationTAS12855810 
GO:0042730fibrinolysisIDA12855810 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005624membrane fractionIDA15297306 
GO:0005886plasma membraneEXP1939645 |8608228 
GO:0005886plasma membraneIDA15297306 
GO:0005887integral to plasma membraneTAS3353370 
GO:0031092platelet alpha granule membraneEXP8608228 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CTSGCG | MGC23078cathepsin G-HPRD8400294 
F11FXI | MGC141891coagulation factor XI-HPRD,BioGRID11696542 
F12HAE3 | HAEX | HAFcoagulation factor XII (Hageman factor)-HPRD,BioGRID10801853 
F2PTcoagulation factor II (thrombin)-HPRD2933256 
FLNAABP-280 | ABPX | DKFZp434P031 | FLN | FLN1 | FMD | MNS | NHBP | OPD | OPD1 | OPD2filamin A, alpha (actin binding protein 280)-HPRD,BioGRID11700320 
FLNBABP-278 | AOI | DKFZp686A1668 | DKFZp686O033 | FH1 | FLN1L | LRS1 | SCT | TABP | TAPfilamin B, beta (actin binding protein 278)-HPRD,BioGRID9651345 
GP1BABSS | CD42B | CD42b-alpha | GP1B | MGC34595glycoprotein Ib (platelet), alpha polypeptide-HPRD12183630 
GP5CD42dglycoprotein V (platelet)-HPRD,BioGRID1730602 
GP9CD42a | GPIXglycoprotein IX (platelet)-HPRD2436691 
ITGAMCD11B | CR3A | MAC-1 | MAC1A | MGC117044 | MO1A | SLEB6integrin, alpha M (complement component 3 receptor 3 subunit)-HPRD10899906 
KNG1BDK | KNGkininogen 1-HPRD9269768 
OSGEPFLJ20411 | GCPL1 | KAE1 | OSGEP1 | PRSMG1O-sialoglycoprotein endopeptidase-HPRD9092683 
SELPCD62 | CD62P | FLJ45155 | GMP140 | GRMP | LECAM3 | PADGEM | PSELselectin P (granule membrane protein 140kDa, antigen CD62)-HPRD,BioGRID10499919 
VWFF8VWF | VWDvon Willebrand factor-HPRD,BioGRID6336654 |12087105 
|12183630 
YWHAZKCIP-1 | MGC111427 | MGC126532 | MGC138156tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide-HPRD,BioGRID8631758 |9454760 
|10627461|9454760 
 


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