Gene Page: GPR6

Summary
GeneID  2830
Symbol  GPR6
Synonyms  -
Description  G protein-coupled receptor 6
See related  HGNC:4515|MIM:600553|Ensembl:ENSG00000146360|HPRD:02775|
Locus tag  -
Gene type  protein-coding
Map location  6q21
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
TOLLIP0.890.87
KCNK10.890.82
DNM10.890.88
EXTL10.890.84
CNTNAP10.890.89
FAIM20.890.90
MFSD40.890.88
TMEM1300.880.89
TYRO30.880.82
MAST30.880.85
Top 10 negatively co-expressed genes
GTF3C6-0.50-0.47
PDE9A-0.49-0.53
BCL7C-0.48-0.55
RBMX2-0.48-0.56
C9orf46-0.48-0.51
FAM36A-0.48-0.39
FADS2-0.47-0.42
TRAF4-0.47-0.53
TUBB2B-0.47-0.52
KIAA1949-0.46-0.41
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0001619lysosphingolipid and lysophosphatidic acid receptor activityIEA-
GO:0004872receptor activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007204elevation of cytosolic calcium ion concentrationIEA-
GO:0007186G-protein coupled receptor protein signaling pathwayTAS7832990 
GO:0007165signal transductionIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005886plasma membraneIEA-
GO:0005887integral to plasma membraneTAS7832990 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
MULLIGHAN_NPM1_MUTATED_SIGNATURE_1_DN 12686All SZGR genes in this pathway
MULLIGHAN_NPM1_MUTATED_SIGNATURE_2_DN 7746All SZGR genes in this pathway
MULLIGHAN_NPM1_SIGNATURE_3_DN 162116All SZGR genes in this pathway
SCHLESINGER_H3K27ME3_IN_NORMAL_AND_METHYLATED_IN_CANCER 2821All SZGR genes in this pathway
BENPORATH_EED_TARGETS 1062725All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3 1118744All SZGR genes in this pathway
HENDRICKS_SMARCA4_TARGETS_DN 5334All SZGR genes in this pathway
HILLION_HMGA1_TARGETS 9071All SZGR genes in this pathway
YAGI_AML_WITH_T_8_21_TRANSLOCATION 368247All SZGR genes in this pathway
MARTENS_TRETINOIN_RESPONSE_UP 857456All SZGR genes in this pathway
FIGUEROA_AML_METHYLATION_CLUSTER_1_UP 12561All SZGR genes in this pathway


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