Gene Page: GPR17

Summary
GeneID  2840
Symbol  GPR17
Synonyms  DKFZp686M18273
Description  G protein-coupled receptor 17
See related  HGNC:4471|MIM:603071|Ensembl:ENSG00000144230|HPRD:04351|
Locus tag  -
Gene type  protein-coding
Map location  2q21
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.023 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00755 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
P2RY120.840.89
CD860.840.82
ADORA30.820.81
RGS100.810.85
C1QC0.810.81
TBXAS10.800.81
SAMSN10.800.84
C1QA0.790.77
RNASE60.790.79
LAPTM50.780.81
Top 10 negatively co-expressed genes
HIP1R-0.38-0.39
DMPK-0.35-0.43
TNKS1BP1-0.35-0.33
SMTN-0.35-0.48
SAFB2-0.34-0.31
CEP250-0.34-0.30
PABPN1-0.33-0.38
UPF3A-0.33-0.40
SFRS16-0.33-0.33
UCP3-0.33-0.36
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004872receptor activityIEA-
GO:0004950chemokine receptor activityTAS8558062 
GO:0045028purinergic nucleotide receptor activity, G-protein coupledIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007186G-protein coupled receptor protein signaling pathwayTAS8558062 
GO:0007165signal transductionIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005886plasma membraneIEA-
GO:0005887integral to plasma membraneTAS8558062 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
REACTOME_GASTRIN_CREB_SIGNALLING_PATHWAY_VIA_PKC_AND_MAPK 205136All SZGR genes in this pathway
REACTOME_SIGNALING_BY_GPCR 920449All SZGR genes in this pathway
REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS 305177All SZGR genes in this pathway
REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS 184116All SZGR genes in this pathway
REACTOME_P2Y_RECEPTORS 125All SZGR genes in this pathway
REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS 168All SZGR genes in this pathway
REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS 166All SZGR genes in this pathway
REACTOME_GPCR_DOWNSTREAM_SIGNALING 805368All SZGR genes in this pathway
REACTOME_G_ALPHA_I_SIGNALLING_EVENTS 195114All SZGR genes in this pathway
REACTOME_GPCR_LIGAND_BINDING 408246All SZGR genes in this pathway
HARRIS_BRAIN_CANCER_PROGENITORS 4423All SZGR genes in this pathway
RIGGI_EWING_SARCOMA_PROGENITOR_UP 430288All SZGR genes in this pathway
TAVAZOIE_METASTASIS 10868All SZGR genes in this pathway
VERHAAK_GLIOBLASTOMA_PRONEURAL 177132All SZGR genes in this pathway
FIGUEROA_AML_METHYLATION_CLUSTER_3_DN 4224All SZGR genes in this pathway
FIGUEROA_AML_METHYLATION_CLUSTER_5_DN 5031All SZGR genes in this pathway
FIGUEROA_AML_METHYLATION_CLUSTER_6_DN 3819All SZGR genes in this pathway
GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN 1080713All SZGR genes in this pathway


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