|
GeneID |
2915
|
Symbol |
GRM5
|
Synonyms |
GPRC1E|MGLUR5|MGLUR5A|MGLUR5B|mGlu5
|
Description |
glutamate receptor, metabotropic 5 |
See related |
HGNC:4597|MIM:604102|Ensembl:ENSG00000168959| |
Locus tag |
- |
Gene type |
protein-coding |
Map location |
11q14.2-q14.3 |
|
|
|
Gene set name |
Method of gene set |
Evidence |
Info |
Association | A combined odds ratio method (Sun et al. 2008), association studies | 1 | Link to SZGene | Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenics, schizophrenia] | Click to show detail | GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 2 | | Network | Shortest path distance of core genes in the Human protein-protein interaction network | Contribution to shortest path in PPI network: 0.104 | |
|
|
General Gene Expression (microarray) ? |
|
|
|
Gene Expression in Brain Regions (new) |
|
|
Top co-expressed genes in Brain Regions (new) |
|
Gene | Pearson's Correlation | Spearman's Correlation | | |
Top 10 positively co-expressed genes |
MARCH6 | 0.95 | 0.97 | | |
KIF1B | 0.95 | 0.96 | | |
KIAA1219 | 0.95 | 0.96 | | |
PCNX | 0.95 | 0.96 | | |
DENND5B | 0.95 | 0.96 | | |
PUM2 | 0.94 | 0.96 | | |
AP1G1 | 0.94 | 0.96 | | |
WHSC1L1 | 0.94 | 0.96 | | |
DYRK1A | 0.94 | 0.96 | | |
AVL9 | 0.94 | 0.96 | | |
Top 10 negatively co-expressed genes | FXYD1 | -0.75 | -0.84 | | |
AF347015.31 | -0.73 | -0.83 | | |
MT-CO2 | -0.72 | -0.84 | | |
HIGD1B | -0.72 | -0.84 | | |
HSD17B14 | -0.71 | -0.76 | | |
AF347015.33 | -0.70 | -0.79 | | |
TLCD1 | -0.70 | -0.79 | | |
AC021016.1 | -0.70 | -0.79 | | |
TSC22D4 | -0.70 | -0.75 | | |
MT-CYB | -0.70 | -0.80 | | |
|
Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
---|
GO:0004872 | receptor activity | IEA | | - |
Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
---|
GO:0007268 | synaptic transmission | TAS | neuron, Synap, Neurotransmitter (GO term level: 6) | 7908515 |
GO:0007206 | metabotropic glutamate receptor, phospholipase C activating pathway | TAS | glutamate (GO term level: 10) | 7908515 |
GO:0007186 | G-protein coupled receptor protein signaling pathway | IEA | | - |
GO:0007165 | signal transduction | IEA | | - |
Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
---|
GO:0016021 | integral to membrane | IEA | | - |
GO:0005886 | plasma membrane | IEA | | - |
GO:0005887 | integral to plasma membrane | TAS | | 7908515 |
|
|
|
|
|
|
|
|
- SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
- Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.
|