Gene Page: GSTP1

Summary
GeneID  2950
Symbol  GSTP1
Synonyms  DFN7|FAEES3|GST3|PI
Description  glutathione S-transferase pi 1
See related  HGNC:4638|MIM:134660|Ensembl:ENSG00000084207|HPRD:00614|
Locus tag  -
Gene type  protein-coding
Map location  11q13
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenic, schizophrenia]Click to show detail
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
C17orf800.880.89
MAP3K70.880.88
SAR1A0.870.87
ZC3H140.870.86
MAP3K7IP20.870.86
EIF2AK10.870.84
SMU10.870.84
TSN0.870.84
YME1L10.870.87
DCLRE1A0.860.85
Top 10 negatively co-expressed genes
MT-CO2-0.75-0.74
AF347015.31-0.74-0.73
AF347015.21-0.72-0.71
MT-CYB-0.72-0.72
AF347015.8-0.71-0.72
HIGD1B-0.71-0.72
IFI27-0.70-0.73
AF347015.33-0.69-0.69
AF347015.2-0.69-0.68
FXYD1-0.68-0.71
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI16636664 
GO:0004364glutathione transferase activityIEA-
GO:0016740transferase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007417central nervous system developmentTASBrain (GO term level: 6)9802272 
GO:0008152metabolic processIEA-
GO:0006916anti-apoptosisTAS16130169 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005737cytoplasmTAS16130169 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
FANCCFA3 | FAC | FACC | FLJ14675Fanconi anemia, complementation group CAffinity Capture-Western
Two-hybrid		BioGRID11433346 |14499622 
GSTP1DFN7 | FAEES3 | GST3 | PIglutathione S-transferase pi 1-HPRD,BioGRID9398518 
HIST4H4H4/p | MGC24116histone cluster 4, H4HIST4H4 (H4) interacts with the GSTP1 promoter.BIND15765097 
MAPK8JNK | JNK1 | JNK1A2 | JNK21B1/2 | PRKM8 | SAPK1mitogen-activated protein kinase 8-HPRD,BioGRID11279197 |12646564 
PNO1KHRBP1partner of NOB1 homolog (S. cerevisiae)Two-hybridBioGRID16169070 
PTNHARP | HBGF8 | HBNF | NEGF1pleiotrophinTwo-hybridBioGRID16169070 
TGM2G-ALPHA-h | GNAH | TG2 | TGCtransglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)Affinity Capture-WesternBioGRID9973324 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_GLUTATHIONE_METABOLISM 5034All SZGR genes in this pathway
KEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450 7044All SZGR genes in this pathway
KEGG_DRUG_METABOLISM_CYTOCHROME_P450 7247All SZGR genes in this pathway
KEGG_PATHWAYS_IN_CANCER 328259All SZGR genes in this pathway
KEGG_PROSTATE_CANCER 8975All SZGR genes in this pathway
REACTOME_BIOLOGICAL_OXIDATIONS 13991All SZGR genes in this pathway
REACTOME_GLUTATHIONE_CONJUGATION 2313All SZGR genes in this pathway
REACTOME_PHASE_II_CONJUGATION 7042All SZGR genes in this pathway
WATANABE_RECTAL_CANCER_RADIOTHERAPY_RESPONSIVE_DN 9251All SZGR genes in this pathway
LIU_PROSTATE_CANCER_DN 481290All SZGR genes in this pathway
ONKEN_UVEAL_MELANOMA_DN 526357All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN 455304All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_DN 460312All SZGR genes in this pathway
TIMOFEEVA_GROWTH_STRESS_VIA_STAT1_DN 1612All SZGR genes in this pathway
BASAKI_YBX1_TARGETS_UP 290177All SZGR genes in this pathway
WAMUNYOKOLI_OVARIAN_CANCER_LMP_UP 265158All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_DN 537339All SZGR genes in this pathway
KOKKINAKIS_METHIONINE_DEPRIVATION_48HR_UP 12895All SZGR genes in this pathway
KOKKINAKIS_METHIONINE_DEPRIVATION_96HR_UP 11784All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_UP 530342All SZGR genes in this pathway
OUELLET_CULTURED_OVARIAN_CANCER_INVASIVE_VS_LMP_DN 3520All SZGR genes in this pathway
LI_LUNG_CANCER 4130All SZGR genes in this pathway
FARMER_BREAST_CANCER_BASAL_VS_LULMINAL 330215All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_UP 309199All SZGR genes in this pathway
DAIRKEE_TERT_TARGETS_UP 380213All SZGR genes in this pathway
YANG_BREAST_CANCER_ESR1_LASER_DN 5038All SZGR genes in this pathway
OHM_METHYLATED_IN_ADULT_CANCERS 2723All SZGR genes in this pathway
OHM_EMBRYONIC_CARCINOMA_UP 65All SZGR genes in this pathway
LOPEZ_MBD_TARGETS 957597All SZGR genes in this pathway
RAHMAN_TP53_TARGETS_PHOSPHORYLATED 2118All SZGR genes in this pathway
GOTZMANN_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_DN 206136All SZGR genes in this pathway
BENPORATH_MYC_TARGETS_WITH_EBOX 230156All SZGR genes in this pathway
NIKOLSKY_BREAST_CANCER_11Q12_Q14_AMPLICON 15893All SZGR genes in this pathway
KLEIN_PRIMARY_EFFUSION_LYMPHOMA_DN 5842All SZGR genes in this pathway
CHEN_LUNG_CANCER_SURVIVAL 2822All SZGR genes in this pathway
FERNANDEZ_BOUND_BY_MYC 182116All SZGR genes in this pathway
XU_RESPONSE_TO_TRETINOIN_AND_NSC682994_UP 1713All SZGR genes in this pathway
LEI_MYB_TARGETS 318215All SZGR genes in this pathway
CROMER_METASTASIS_DN 8158All SZGR genes in this pathway
KAAB_FAILED_HEART_ATRIUM_DN 14199All SZGR genes in this pathway
NATSUME_RESPONSE_TO_INTERFERON_BETA_DN 5233All SZGR genes in this pathway
ZHANG_PROLIFERATING_VS_QUIESCENT 5141All SZGR genes in this pathway
JOSEPH_RESPONSE_TO_SODIUM_BUTYRATE_UP 3121All SZGR genes in this pathway
ZHONG_SECRETOME_OF_LUNG_CANCER_AND_FIBROBLAST 13293All SZGR genes in this pathway
LOPES_METHYLATED_IN_COLON_CANCER_DN 2826All SZGR genes in this pathway
MARTINEZ_RB1_TARGETS_DN 543317All SZGR genes in this pathway
MARTINEZ_TP53_TARGETS_DN 593372All SZGR genes in this pathway
MARTINEZ_RB1_AND_TP53_TARGETS_DN 591366All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_DN 540340All SZGR genes in this pathway
HOQUE_METHYLATED_IN_CANCER 5645All SZGR genes in this pathway
SMID_BREAST_CANCER_LUMINAL_B_DN 564326All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_UP 648398All SZGR genes in this pathway
HONMA_DOCETAXEL_RESISTANCE 3423All SZGR genes in this pathway
GRADE_COLON_CANCER_UP 871505All SZGR genes in this pathway
HSIAO_HOUSEKEEPING_GENES 389245All SZGR genes in this pathway
YAMASHITA_LIVER_CANCER_STEM_CELL_DN 7651All SZGR genes in this pathway
LI_PROSTATE_CANCER_EPIGENETIC 3022All SZGR genes in this pathway
HOSHIDA_LIVER_CANCER_SUBCLASS_S1 237159All SZGR genes in this pathway
DANG_BOUND_BY_MYC 1103714All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_17 181101All SZGR genes in this pathway
PASINI_SUZ12_TARGETS_UP 11265All SZGR genes in this pathway


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