Gene Page: GTF3C1

Summary
GeneID  2975
Symbol  GTF3C1
Synonyms  DKFZp686A111|TFIIIC|TFIIIC220|TFIIICalpha
Description  general transcription factor IIIC, polypeptide 1, alpha 220kDa
See related  HGNC:4664|MIM:603246|Ensembl:ENSG00000077235|HPRD:07540|
Locus tag  -
Gene type  protein-coding
Map location  16p12
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.01775 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
HIGD1A0.860.86
CD590.850.84
GSTO10.830.83
IFIT10.830.85
NDUFA40.820.81
CTBS0.810.77
HERC60.810.83
TMEM220.810.87
C1orf570.800.66
HOPX0.800.78
Top 10 negatively co-expressed genes
KIAA1949-0.53-0.68
VAV2-0.52-0.65
AXIN1-0.52-0.62
UPF3A-0.51-0.70
SH3BP2-0.51-0.74
ZNF311-0.51-0.63
MARCKSL1-0.51-0.64
VASH1-0.51-0.64
RTF1-0.51-0.61
GMIP-0.51-0.55
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003677DNA bindingIC17409385 
GO:0003709RNA polymerase III transcription factor activityIC17409385 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0042797tRNA transcription from RNA polymerase III promoterIC17409385 
GO:00427915S class rRNA transcriptionIC17409385 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0000127transcription factor TFIIIC complexIDA17409385 
GO:0005634nucleusIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
AKTIPFT1 | FTSAKT interacting proteinTwo-hybridBioGRID16169070 
ASCC2ASC1p100activating signal cointegrator 1 complex subunit 2Two-hybridBioGRID16169070 
C8orf30AFLJ40907chromosome 8 open reading frame 30ATwo-hybridBioGRID16169070 
CHN1ARHGAP2 | CHN | DURS2 | RHOGAP2chimerin (chimaerin) 1Two-hybridBioGRID16169070 
CPE-carboxypeptidase ETwo-hybridBioGRID16169070 
EZH2ENX-1 | EZH1 | KMT6 | MGC9169enhancer of zeste homolog 2 (Drosophila)Two-hybridBioGRID16169070 
FGFR3ACH | CD333 | CEK2 | HSFGFR3EX | JTK4fibroblast growth factor receptor 3Two-hybridBioGRID16169070 
GTF3C4FLJ21002 | KAT12 | MGC138450 | TFIII90 | TFIIIC90 | TFIIICdelta | TFiiiC2-90general transcription factor IIIC, polypeptide 4, 90kDa-HPRD,BioGRID10523658 
IGFBP3BP-53 | IBP3insulin-like growth factor binding protein 3Two-hybridBioGRID16169070 
KLF6BCD1 | COPEB | CPBP | DKFZp686N0199 | GBF | PAC1 | ST12 | ZF9Kruppel-like factor 6Two-hybridBioGRID16169070 
MAPK10FLJ12099 | FLJ33785 | JNK3 | JNK3A | MGC50974 | PRKM10 | p493F12 | p54bSAPKmitogen-activated protein kinase 10Two-hybridBioGRID16169070 
NHP2L115.5K | FA-1 | FA1 | NHPX | OTK27 | SNU13 | SPAG12 | SSFA1NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)Two-hybridBioGRID16169070 
POLR3CRPC3 | RPC62polymerase (RNA) III (DNA directed) polypeptide C (62kD)Affinity Capture-WesternBioGRID10373544 
PRPF38AFLJ14936 | MGC3320 | RP5-965L7.1PRP38 pre-mRNA processing factor 38 (yeast) domain containing ATwo-hybridBioGRID16169070 
RBM23CAPERbeta | FLJ10482 | MGC4458 | PP239 | RNPC4RNA binding motif protein 23Two-hybridBioGRID16169070 
TBC1D17FLJ12168TBC1 domain family, member 17Two-hybridBioGRID16169070 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
PARENT_MTOR_SIGNALING_UP 567375All SZGR genes in this pathway
HOLLMANN_APOPTOSIS_VIA_CD40_DN 267178All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_UP 380215All SZGR genes in this pathway
WANG_ESOPHAGUS_CANCER_VS_NORMAL_DN 10166All SZGR genes in this pathway
EBAUER_TARGETS_OF_PAX3_FOXO1_FUSION_DN 4831All SZGR genes in this pathway
GRUETZMANN_PANCREATIC_CANCER_DN 203134All SZGR genes in this pathway
YANG_BREAST_CANCER_ESR1_LASER_UP 3425All SZGR genes in this pathway
SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_UP 479299All SZGR genes in this pathway
MANTOVANI_NFKB_TARGETS_UP 4333All SZGR genes in this pathway
MANTOVANI_VIRAL_GPCR_SIGNALING_UP 8654All SZGR genes in this pathway
BYSTROEM_CORRELATED_WITH_IL5_UP 5130All SZGR genes in this pathway
POMEROY_MEDULLOBLASTOMA_PROGNOSIS_UP 4730All SZGR genes in this pathway
KLEIN_PRIMARY_EFFUSION_LYMPHOMA_UP 5129All SZGR genes in this pathway
PENG_RAPAMYCIN_RESPONSE_DN 245154All SZGR genes in this pathway
THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_DN 225163All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_5 482296All SZGR genes in this pathway
SANSOM_APC_MYC_TARGETS 217138All SZGR genes in this pathway
MILI_PSEUDOPODIA_HAPTOTAXIS_DN 668419All SZGR genes in this pathway
KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP 756494All SZGR genes in this pathway
KIM_ALL_DISORDERS_DURATION_CORR_DN 14690All SZGR genes in this pathway
FIGUEROA_AML_METHYLATION_CLUSTER_3_UP 17097All SZGR genes in this pathway


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