Gene Page: GZMA

Summary
GeneID  3001
Symbol  GZMA
Synonyms  CTLA3|HFSP
Description  granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
See related  HGNC:4708|MIM:140050|Ensembl:ENSG00000145649|HPRD:00771|
Locus tag  -
Gene type  protein-coding
Map location  5q11-q12
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 2 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004252serine-type endopeptidase activityIDAglutamate (GO term level: 7)12819770 
GO:0008233peptidase activityIEA-
GO:0042803protein homodimerization activityIDA12819770 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006508proteolysisIEA-
GO:0019835cytolysisIEA-
GO:0006955immune responseTAS12524539 
GO:0006922cleavage of laminIDA11331782 
GO:0006915apoptosisTAS12524539 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0001772immunological synapseTASSynap (GO term level: 7)12524539 
GO:0005576extracellular regionIEA-
GO:0005634nucleusTAS11909973 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
HMGB2HMG2high-mobility group box 2-HPRD,BioGRID11909973 
NCLC23 | FLJ45706nucleolin-HPRD1860869 
SET2PP2A | I2PP2A | IGAAD | IPP2A2 | PHAPII | TAF-I | TAF-IBETASET nuclear oncogene-HPRD,BioGRID11555662 
 


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