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|
| GeneID |
3002
|
| Symbol |
GZMB
|
| Synonyms |
CCPI|CGL-1|CGL1|CSP-B|CSPB|CTLA1|CTSGL1|HLP|SECT
|
| Description |
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) |
| See related |
HGNC:4709|MIM:123910|Ensembl:ENSG00000100453|HPRD:00476| |
| Locus tag |
- |
| Gene type |
protein-coding |
| Map location |
14q11.2 |
|
| |
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|
| Gene set name |
Method of gene set |
Evidence |
Info |
| GSMA_I | genome scan meta-analysis | Psr: 0.047 | | | GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 3 | |
|
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| General Gene Expression (microarray) ? |
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| Gene Expression in Brain Regions (new) |
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| Top co-expressed genes in Brain Regions (new) |
|
| Gene | Pearson's Correlation | Spearman's Correlation | | |
| Top 10 positively co-expressed genes |
Top 10 negatively co-expressed genes | |
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0004252 | serine-type endopeptidase activity | IEA | glutamate (GO term level: 7) | - |
| GO:0004252 | serine-type endopeptidase activity | TAS | glutamate (GO term level: 7) | 12524539 |
| GO:0003824 | catalytic activity | IEA | | - |
| GO:0005515 | protein binding | IPI | | 11911826 |
| GO:0008233 | peptidase activity | IEA | | - |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0006508 | proteolysis | IEA | | - |
| GO:0019835 | cytolysis | IEA | | - |
| GO:0006922 | cleavage of lamin | IDA | | 11331782 |
| GO:0006915 | apoptosis | TAS | | 12524539 |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0001772 | immunological synapse | TAS | Synap (GO term level: 7) | 12524539 |
| GO:0005829 | cytosol | EXP | | 11114298 |
| GO:0005634 | nucleus | TAS | | 11909973 |
| GO:0005737 | cytoplasm | IDA | | 18029348 |
| GO:0043231 | intracellular membrane-bounded organelle | IDA | | 18029348 |
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