Gene Page: HLA-DMA

Summary
GeneID  3108
Symbol  HLA-DMA
Synonyms  D6S222E|DMA|HLADM|RING6
Description  major histocompatibility complex, class II, DM alpha
See related  HGNC:4934|MIM:142855|Ensembl:ENSG00000204257|HPRD:00830|
Locus tag  DAAP-27A1.5
Gene type  protein-coding
Map location  6p21.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.033 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIEA-
GO:0005515protein bindingTAS10631952 
GO:0032395MHC class II receptor activityNAS8034636 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0002504antigen processing and presentation of peptide or polysaccharide antigen via MHC class IIIEA-
GO:0006461protein complex assemblyIEA-
GO:0016064immunoglobulin mediated immune responseIEA-
GO:0019886antigen processing and presentation of exogenous peptide antigen via MHC class IIIEA-
GO:0008150biological_processND-
GO:0006955immune responseIEA-
GO:0051085chaperone cofactor-dependent protein foldingIEA-
GO:0015031protein transportIEA-
GO:0050778positive regulation of immune responseIEA-
GO:0045059positive thymic T cell selectionIEA-
GO:0045582positive regulation of T cell differentiationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005575cellular_componentND-
GO:0005622intracellularIEA-
GO:0005765lysosomal membraneIEA-
GO:0005771multivesicular bodyIEA-
GO:0016020membraneIEA-
GO:0016021integral to membraneIEA-
GO:0005886plasma membraneEXP11048639 |11827988 |15489916 
|17652306 
GO:0010008endosome membraneIEA-
GO:0042613MHC class II protein complexIEA-
GO:0031902late endosome membraneIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CD74DHLAG | HLADG | Ia-GAMMACD74 molecule, major histocompatibility complex, class II invariant chain-HPRD,BioGRID8574855 
CD824F9 | C33 | GR15 | IA4 | KAI1 | R2 | SAR2 | ST6 | TSPAN27CD82 molecule-HPRD9759843 
HLA-DMBD6S221E | RING7major histocompatibility complex, class II, DM beta-HPRD,BioGRID8139690 |8574855 
HLA-DOAHLA-DNA | HLA-DZA | HLADZmajor histocompatibility complex, class II, DO alpha-HPRD,BioGRID9311912 
HLA-DRAHLA-DRA1major histocompatibility complex, class II, DR alpha-HPRD,BioGRID8574855 |9371817 
|11070170 
HLA-DRB1DRB1 | FLJ76359 | HLA-DR1B | HLA-DRB | HLA-DRB1* | SS1major histocompatibility complex, class II, DR beta 1Reconstituted ComplexBioGRID9371817 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_CELL_ADHESION_MOLECULES_CAMS 13493All SZGR genes in this pathway
KEGG_ANTIGEN_PROCESSING_AND_PRESENTATION 8965All SZGR genes in this pathway
KEGG_INTESTINAL_IMMUNE_NETWORK_FOR_IGA_PRODUCTION 4836All SZGR genes in this pathway
KEGG_TYPE_I_DIABETES_MELLITUS 4438All SZGR genes in this pathway
KEGG_LEISHMANIA_INFECTION 7256All SZGR genes in this pathway
KEGG_ASTHMA 3025All SZGR genes in this pathway
KEGG_AUTOIMMUNE_THYROID_DISEASE 5349All SZGR genes in this pathway
KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS 140100All SZGR genes in this pathway
KEGG_ALLOGRAFT_REJECTION 3834All SZGR genes in this pathway
KEGG_GRAFT_VERSUS_HOST_DISEASE 4231All SZGR genes in this pathway
KEGG_VIRAL_MYOCARDITIS 7358All SZGR genes in this pathway
REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION 9161All SZGR genes in this pathway
REACTOME_IMMUNE_SYSTEM 933616All SZGR genes in this pathway
REACTOME_ADAPTIVE_IMMUNE_SYSTEM 539350All SZGR genes in this pathway
ONKEN_UVEAL_MELANOMA_UP 783507All SZGR genes in this pathway
SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP 351230All SZGR genes in this pathway
GARY_CD5_TARGETS_DN 431263All SZGR genes in this pathway
THUM_SYSTOLIC_HEART_FAILURE_UP 423283All SZGR genes in this pathway
BASAKI_YBX1_TARGETS_DN 384230All SZGR genes in this pathway
GRAHAM_CML_QUIESCENT_VS_NORMAL_QUIESCENT_DN 4732All SZGR genes in this pathway
GAUSSMANN_MLL_AF4_FUSION_TARGETS_A_DN 9061All SZGR genes in this pathway
LINDGREN_BLADDER_CANCER_CLUSTER_2B 392251All SZGR genes in this pathway
LUI_THYROID_CANCER_CLUSTER_5 135All SZGR genes in this pathway
DIRMEIER_LMP1_RESPONSE_LATE_DN 3222All SZGR genes in this pathway
TSUNODA_CISPLATIN_RESISTANCE_DN 5138All SZGR genes in this pathway
YAN_ESCAPE_FROM_ANOIKIS 2419All SZGR genes in this pathway
MORI_LARGE_PRE_BII_LYMPHOCYTE_DN 5839All SZGR genes in this pathway
MORI_IMMATURE_B_LYMPHOCYTE_UP 5335All SZGR genes in this pathway
MORI_MATURE_B_LYMPHOCYTE_UP 9062All SZGR genes in this pathway
ROZANOV_MMP14_TARGETS_UP 266171All SZGR genes in this pathway
LEE_LIVER_CANCER_MYC_TGFA_DN 6544All SZGR genes in this pathway
KLEIN_PRIMARY_EFFUSION_LYMPHOMA_DN 5842All SZGR genes in this pathway
WIELAND_UP_BY_HBV_INFECTION 10166All SZGR genes in this pathway
SANA_RESPONSE_TO_IFNG_UP 7850All SZGR genes in this pathway
YU_MYC_TARGETS_DN 5538All SZGR genes in this pathway
ALCALAY_AML_BY_NPM1_LOCALIZATION_DN 184132All SZGR genes in this pathway
BASSO_CD40_SIGNALING_UP 10176All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_EARLY_PROGENITOR 532309All SZGR genes in this pathway
LEE_AGING_NEOCORTEX_DN 8049All SZGR genes in this pathway
KAYO_CALORIE_RESTRICTION_MUSCLE_DN 8759All SZGR genes in this pathway
MCLACHLAN_DENTAL_CARIES_DN 245144All SZGR genes in this pathway
RODWELL_AGING_KIDNEY_UP 487303All SZGR genes in this pathway
CUI_TCF21_TARGETS_2_UP 428266All SZGR genes in this pathway
MCLACHLAN_DENTAL_CARIES_UP 253147All SZGR genes in this pathway
TUOMISTO_TUMOR_SUPPRESSION_BY_COL13A1_UP 189All SZGR genes in this pathway
HELLER_SILENCED_BY_METHYLATION_UP 282183All SZGR genes in this pathway
GAURNIER_PSMD4_TARGETS 7355All SZGR genes in this pathway
WILENSKY_RESPONSE_TO_DARAPLADIB 2920All SZGR genes in this pathway
BOQUEST_STEM_CELL_DN 216143All SZGR genes in this pathway
BEIER_GLIOMA_STEM_CELL_DN 6642All SZGR genes in this pathway
ICHIBA_GRAFT_VERSUS_HOST_DISEASE_D7_UP 10767All SZGR genes in this pathway
ICHIBA_GRAFT_VERSUS_HOST_DISEASE_35D_UP 13179All SZGR genes in this pathway
LINDSTEDT_DENDRITIC_CELL_MATURATION_D 6844All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
WUNDER_INFLAMMATORY_RESPONSE_AND_CHOLESTEROL_UP 5838All SZGR genes in this pathway
SWEET_LUNG_CANCER_KRAS_UP 491316All SZGR genes in this pathway
HOFFMANN_SMALL_PRE_BII_TO_IMMATURE_B_LYMPHOCYTE_UP 7049All SZGR genes in this pathway
YAGI_AML_WITH_T_8_21_TRANSLOCATION 368247All SZGR genes in this pathway
KOBAYASHI_EGFR_SIGNALING_24HR_UP 10165All SZGR genes in this pathway
HOSHIDA_LIVER_CANCER_SUBCLASS_S1 237159All SZGR genes in this pathway
GUTIERREZ_WALDENSTROEMS_MACROGLOBULINEMIA_2 139All SZGR genes in this pathway
WONG_ADULT_TISSUE_STEM_MODULE 721492All SZGR genes in this pathway
MIKKELSEN_ES_ICP_WITH_H3K4ME3 718401All SZGR genes in this pathway
NIELSEN_SYNOVIAL_SARCOMA_DN 2013All SZGR genes in this pathway
WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_UP 397206All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_3_UP 430288All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_B 549316All SZGR genes in this pathway
KIM_GLIS2_TARGETS_UP 8461All SZGR genes in this pathway
FEVR_CTNNB1_TARGETS_UP 682433All SZGR genes in this pathway
TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_DN 321200All SZGR genes in this pathway
DURAND_STROMA_S_UP 297194All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY 1839928All SZGR genes in this pathway


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.