Gene Page: HLA-DRB3

Summary
GeneID  3125
Symbol  HLA-DRB3
Synonyms  HLA-DR3B|MGC117330
Description  major histocompatibility complex, class II, DR beta 3
See related  HGNC:4951|HPRD:09985|
Locus tag  -
Gene type  protein-coding
Map location  6p21.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0032395MHC class II receptor activityNAS6414998 
GO:0032395MHC class II receptor activityTAS11144299 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0002504antigen processing and presentation of peptide or polysaccharide antigen via MHC class IIIEA-
GO:0007165signal transductionNAS8775462 
GO:0006955immune responseIEA-
GO:0006955immune responseTAS10609818 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0016020membraneIEA-
GO:0016020membraneTAS11144299 
GO:0016021integral to membraneIEA-
GO:0005886plasma membraneEXP11048639 |11827988 |15489916 
|17652306 
GO:0005887integral to plasma membraneNAS6414998 
GO:0042613MHC class II protein complexIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
POMCACTH | CLIP | LPH | MSH | NPP | POCproopiomelanocortin-HPRD,BioGRID7477400 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_CELL_ADHESION_MOLECULES_CAMS 13493All SZGR genes in this pathway
KEGG_ANTIGEN_PROCESSING_AND_PRESENTATION 8965All SZGR genes in this pathway
KEGG_HEMATOPOIETIC_CELL_LINEAGE 8860All SZGR genes in this pathway
KEGG_INTESTINAL_IMMUNE_NETWORK_FOR_IGA_PRODUCTION 4836All SZGR genes in this pathway
KEGG_TYPE_I_DIABETES_MELLITUS 4438All SZGR genes in this pathway
KEGG_LEISHMANIA_INFECTION 7256All SZGR genes in this pathway
KEGG_ASTHMA 3025All SZGR genes in this pathway
KEGG_AUTOIMMUNE_THYROID_DISEASE 5349All SZGR genes in this pathway
KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS 140100All SZGR genes in this pathway
KEGG_ALLOGRAFT_REJECTION 3834All SZGR genes in this pathway
KEGG_GRAFT_VERSUS_HOST_DISEASE 4231All SZGR genes in this pathway
KEGG_VIRAL_MYOCARDITIS 7358All SZGR genes in this pathway
REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION 9161All SZGR genes in this pathway
REACTOME_TCR_SIGNALING 5446All SZGR genes in this pathway
REACTOME_DOWNSTREAM_TCR_SIGNALING 3732All SZGR genes in this pathway
REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS 1615All SZGR genes in this pathway
REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE 1414All SZGR genes in this pathway
REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES 2725All SZGR genes in this pathway
REACTOME_PD1_SIGNALING 1814All SZGR genes in this pathway
REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY 6348All SZGR genes in this pathway
REACTOME_INTERFERON_GAMMA_SIGNALING 6348All SZGR genes in this pathway
REACTOME_INTERFERON_SIGNALING 159116All SZGR genes in this pathway
REACTOME_IMMUNE_SYSTEM 933616All SZGR genes in this pathway
REACTOME_ADAPTIVE_IMMUNE_SYSTEM 539350All SZGR genes in this pathway
REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM 270204All SZGR genes in this pathway
HAMAI_APOPTOSIS_VIA_TRAIL_DN 186107All SZGR genes in this pathway
CAVARD_LIVER_CANCER_MALIGNANT_VS_BENIGN 3219All SZGR genes in this pathway
TSUNODA_CISPLATIN_RESISTANCE_DN 5138All SZGR genes in this pathway
GOERING_BLOOD_HDL_CHOLESTEROL_QTL_CIS 137All SZGR genes in this pathway
SANA_RESPONSE_TO_IFNG_UP 7850All SZGR genes in this pathway
HENDRICKS_SMARCA4_TARGETS_DN 5334All SZGR genes in this pathway
ACEVEDO_NORMAL_TISSUE_ADJACENT_TO_LIVER_TUMOR_UP 17496All SZGR genes in this pathway
GAURNIER_PSMD4_TARGETS 7355All SZGR genes in this pathway
LINDSTEDT_DENDRITIC_CELL_MATURATION_C 6949All SZGR genes in this pathway
DANG_BOUND_BY_MYC 1103714All SZGR genes in this pathway


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