Gene Page

Home
Datasets
Search
Analysis & Tools
Documents
About SZGR
Quick search: (e.g. 207 or AKT)

Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

Gene Ranking Integration

Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

Release Site Map Support Contact us

Gene Page: APBA1

Summary

GeneID

320

Symbol

APBA1

Synonyms

D9S411E|MINT1|X11|X11A|X11ALPHA

Description

amyloid beta (A4) precursor protein-binding, family A, member 1

Locus tag

Gene type

protein-coding

Map location

9q13-q21.1

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GO_Annotation

Mapping neuro-related keywords to Gene Ontology annotations

Hits with neuro-related keywords: 4

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

DSTYK

0.85

0.87

TRAPPC10

0.84

0.86

BACE1

0.83

0.86

HLCS

0.82

0.85

DYNC1LI2

0.82

0.83

CDC42BPA

0.82

0.85

TGOLN2

0.82

0.85

GRB10

0.82

C9orf5

0.81

0.84

KIAA0232

0.81

0.84

Top 10 negatively co-expressed genes

AF347015.21

-0.59

-0.53

C1orf54

-0.56

C1orf61

-0.55

-0.59

GNG11

-0.53

-0.50

VAMP5

-0.53

-0.47

IL32

-0.52

-0.49

MT-CO2

-0.51

-0.49

ENHO

-0.51

-0.52

AF347015.31

-0.51

-0.49

C16orf74

-0.51

-0.53

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005515

protein binding

IPI

8887653

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0007268

synaptic transmission

TAS

neuron, Synap, Neurotransmitter (GO term level: 6)

9753324

GO:0008088

axon cargo transport

TAS

axon (GO term level: 8)

9822620

GO:0007399

nervous system development

TAS

neurite (GO term level: 5)

9753324

GO:0007155

cell adhesion

TAS

9753324

GO:0006461

protein complex assembly

TAS

9614075 |9753324

GO:0006886

intracellular protein transport

TAS

9614075

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0008021

synaptic vesicle

TAS

Synap, Neurotransmitter (GO term level: 12)

9753324

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
APBB1	FE65 \| MGC:9072 \| RIR	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	X11alpha interacts with APP.	BIND	11115513
APP	AAA \| ABETA \| ABPP \| AD1 \| APPI \| CTFgamma \| CVAP \| PN2	amyloid beta (A4) precursor protein	-	HPRD,BioGRID	8887653
			APPswe interacts with X11-alpha.	BIND	12849748 \|14756819
			Beta-APP interacts with X11.	BIND	8887653
CASK	CAGH39 \| CMG \| FLJ22219 \| FLJ31914 \| LIN2 \| MICPCH \| TNRC8	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	X11-ALPHA interacts with Lin-2.	BIND	9822620
CASK	CAGH39 \| CMG \| FLJ22219 \| FLJ31914 \| LIN2 \| MICPCH \| TNRC8		-	HPRD,BioGRID	9753324 \|9822620 \|9952408\|9822620 \|9952408
CCS	MGC138260	copper chaperone for superoxide dismutase	-	HPRD,BioGRID	11115513
CCS	MGC138260	copper chaperone for superoxide dismutase	X11alpha interacts with CCS.	BIND	11115513
CNTNAP3	CASPR3 \| CNTNAP3A \| RP11-138L21.1 \| RP11-290L7.1	contactin associated protein-like 3	-	HPRD,BioGRID	12093160
CNTNAP4	CASPR4 \| KIAA1763	contactin associated protein-like 4	-	HPRD,BioGRID	12093160
DLG1	DKFZp761P0818 \| DKFZp781B0426 \| DLGH1 \| SAP97 \| dJ1061C18.1.1 \| hdlg	discs, large homolog 1 (Drosophila)	Affinity Capture-Western	BioGRID	14960569
HTR2C	5-HT2C \| 5-HTR2C \| HTR1C	5-hydroxytryptamine (serotonin) receptor 2C	-	HPRD,BioGRID	12006486
KCNJ12	FLJ14167 \| IRK2 \| KCNJN1 \| Kir2.2 \| Kir2.2v \| hIRK \| hIRK1 \| hkir2.2x \| kcnj12x	potassium inwardly-rectifying channel, subfamily J, member 12	-	HPRD,BioGRID	14960569 \|15024025
KIF17	KIAA1405 \| KIF17B \| KIF3X	kinesin family member 17	-	HPRD	12514209
LIN7A	LIN-7A \| LIN7 \| MALS-1 \| MGC148143 \| TIP-33 \| VELI1	lin-7 homolog A (C. elegans)	Affinity Capture-Western	BioGRID	9822620
LIN7B	LIN-7B \| MALS-2 \| MALS2 \| VELI2	lin-7 homolog B (C. elegans)	-	HPRD,BioGRID	9753324
LIN7C	FLJ11215 \| LIN-7-C \| LIN-7C \| MALS-3 \| MALS3 \| VELI3	lin-7 homolog C (C. elegans)	Affinity Capture-Western	BioGRID	14960569
NOTCH1	TAN1 \| hN1	Notch homolog 1, translocation-associated (Drosophila)	Notch1 interacts with X11-alpha. This interaction was modelled on a demonstrated interaction between mouse Notch1 and human X11-alpha.	BIND	14756819
NRXN1	DKFZp313P2036 \| FLJ35941 \| Hs.22998 \| KIAA0578	neurexin 1	-	HPRD,BioGRID	11036064
PSEN1	AD3 \| FAD \| PS1 \| S182	presenilin 1	-	HPRD	12196555
PSEN2	AD3L \| AD4 \| PS2 \| STM2	presenilin 2 (Alzheimer disease 4)	Affinity Capture-Western	BioGRID	12196555
STX1A	HPC-1 \| STX1 \| p35-1	syntaxin 1A (brain)	-	HPRD	9395480
STXBP1	EIEE4 \| MUNC18-1 \| UNC18 \| hUNC18 \| rbSec1	syntaxin binding protein 1	-	HPRD	9395480

Pathway annotation

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-103/107	60	66	1A	hsa-miR-103^brain	AGCAGCAUUGUACAGGGCUAUGA
miR-103/107	60	66	1A	hsa-miR-107^brain	AGCAGCAUUGUACAGGGCUAUCA
miR-185	152	158	m8	hsa-miR-185^brain	UGGAGAGAAAGGCAGUUC
miR-24	533	540	1A,m8	hsa-miR-24^SZ	UGGCUCAGUUCAGCAGGAACAG

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.