|
GeneID |
3249
|
Symbol |
HPN
|
Synonyms |
TMPRSS1
|
Description |
hepsin (transmembrane protease, serine 1) |
See related |
HGNC:5155|MIM:142440|Ensembl:ENSG00000105707|HPRD:00801| |
Locus tag |
- |
Gene type |
protein-coding |
Map location |
19q11-q13.2 |
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|
|
Gene set name |
Method of gene set |
Evidence |
Info |
GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 1 | |
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General Gene Expression (microarray) ? |
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Gene Expression in Brain Regions (new) |
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|
Top co-expressed genes in Brain Regions (new) |
|
Gene | Pearson's Correlation | Spearman's Correlation | | |
Top 10 positively co-expressed genes |
ETS2 | 0.86 | 0.84 | | |
SIRPA | 0.86 | 0.83 | | |
SV2B | 0.85 | 0.76 | | |
MAST3 | 0.85 | 0.76 | | |
TYRO3 | 0.85 | 0.76 | | |
MFSD4 | 0.84 | 0.77 | | |
LRRK1 | 0.84 | 0.83 | | |
RASGRF2 | 0.84 | 0.77 | | |
BMPER | 0.84 | 0.84 | | |
SUSD5 | 0.84 | 0.80 | | |
Top 10 negatively co-expressed genes | HEBP2 | -0.46 | -0.61 | | |
BCL7C | -0.46 | -0.54 | | |
SH2D2A | -0.42 | -0.44 | | |
TRAF4 | -0.41 | -0.45 | | |
KIAA1949 | -0.41 | -0.26 | | |
PDE9A | -0.41 | -0.36 | | |
TUBB2B | -0.41 | -0.35 | | |
RPS19P3 | -0.40 | -0.54 | | |
RPL35 | -0.40 | -0.48 | | |
RPL18 | -0.40 | -0.50 | | |
|
Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
---|
GO:0004252 | serine-type endopeptidase activity | IEA | glutamate (GO term level: 7) | - |
GO:0005044 | scavenger receptor activity | IEA | | - |
GO:0008233 | peptidase activity | IEA | | - |
Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
---|
GO:0006508 | proteolysis | IEA | | - |
Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0005737 | cytoplasm | IDA | | 18029348 |
GO:0005886 | plasma membrane | IEA | | - |
GO:0005887 | integral to plasma membrane | TAS | | 1885621 |
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- SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
- Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.
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